Note 3 - Major Customers and Suppliers (Details Textual)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Number of Vendors	3	3
Sales Revenue, Net [Member] | Customer Concentration Risk [Member]
Number of Major Customers	4	3
Sales Revenue, Net [Member] | Customer Concentration Risk [Member] | Four Major Customer [Member]
Concentration Risk, Percentage	57.00%
Sales Revenue, Net [Member] | Customer Concentration Risk [Member] | Three Major Customers [Member]
Concentration Risk, Percentage		59.00%
Accounts Receivable [Member] | Customer Concentration Risk [Member]
Number of Major Customers	4
Accounts Receivable [Member] | Customer Concentration Risk [Member] | Four Major Customer [Member]
Concentration Risk, Percentage	31.00%
Accounts Receivable [Member] | Customer Concentration Risk [Member] | Three Major Customers [Member]
Concentration Risk, Percentage		27.00%
Sales Revenue, Product Line [Member] | Product Concentration Risk [Member] | Biopharmaceuticals [Member]
Concentration Risk, Percentage	17.00%	28.00%
Sales Revenue, Product Line [Member] | Product Concentration Risk [Member] | Basic Natural and Chemically Modified Cyclodexterins [Member]
Concentration Risk, Percentage	71.00%	71.00%
Sales Revenue, Product Line [Member] | Product Concentration Risk [Member] | Cyclodexterin Complexes [Member]
Concentration Risk, Percentage	12.00%	1.00%