SECURITIES AND EXCHANGE COMMISSION

                             Washington, D. C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934

                          Date of Report: July 19, 2005

                               CTD HOLDINGS, INC.
                               ------------------
             (Exact name of registrant as specified in its charter)

   Florida                    0-24930                        59-3029743
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(State or other         Commission File No.      IRS Employer Identification No.
jurisdiction of
incorporation)


              27317 N.W. 78th Avenue, High Springs, Florida, 32643
              ----------------------------------------------------
               (Address of principal executive offices) (Zip Code)


        Registrant's telephone number, including area code: 386-454-0887

            --------------------------------------------------------
          (Former name or former address, if changed since last report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions:

[ ]  Written communications  pursuant to Rule 425 under the Securities Act (17
     CFR 230.425)

[ ]  Soliciting  material  pursuant to rule 14a-12 under the Exchange Act (17
     CFR 240.14a-12)

[ ]  Pre-commencement  communications  pursuant  to Rule  14d-2(b)  under the
     Exchange Act (17CFR 240.14d-2(b))

[ ]  Pre-commencement  communications  pursuant  to Rule  13e-4(c)  under the
     Exchange Act (17 CFR 240.13e-4(c))



Item 4.01  Changes In Registrant's Certifying Accountant.

     On July 19,  2005,  CTD  Holdings,  Inc.  (hereinafter,  the  "Registrant")
engaged Baumann,  Raymondo & Company,  P.A. as its independent  auditors for the
year ending  December 31, 2005,  to replace the firm of James Moore & Co.,  P.L.
which was  dismissed as its auditors  effective  July 19, 2005.  The decision to
change auditors was approved by the Registrant's Board of Directors.

     The  reports  of  James  Moore & Co.  on the  financial  statements  of the
Registrant  for the years ended December 31, 2003, and December 31, 2004 did not
contain an adverse  opinion or a disclaimer of opinion and were not qualified or
modified as to uncertainty, audit scope or accounting principles.

     There  were  no   disagreements   with  James  Moore  &  Co.,  P.L.,  which
disagreements,  if not resolved to the  satisfaction of James Moore & Co., P.L.,
would have caused it to make reference to the subject matter of the disagreement
in the report, on any matters of accounting  principles or practices,  financial
statement  disclosure or auditing  scope and  procedures in connection  with the
audits of the Registrant's  consolidated  financial  statements for the two-year
period  ended  December 31, 2004,  or with regard to the  Company's  most recent
10-QSB filed May 13, 2005.


Item 9.01.  Financial Statements and Exhibits

Exhibit 9.01-16    Letter of Consent to Dismissal By                  Attached
                   James Moore & Co., P.L.                            Hereto


                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.

Dated: July 20, 2005             CTD HOLDINGS, INC.
                                 (Registrant)

                                 /s/ C.E. Rick Strattan
                                 --------------------------------------
                                 C. E. RICK STRATTAN, President, Chief
                                 Executive Officer, and Chief Financial Officer