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Equity Incentive Plans (Summary of Stock Option Activity) (Details) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2022
Equity Incentive Plans    
Shares, Balance Beginning 3,352,803  
Shares, Granted 17,500  
Shares, Forfeited/Cancelled (4,874)  
Shares, Balance Ending 3,365,429 3,352,803
Vested and expected to vest at March 31, 2022 3,365,429  
Exercisable at March 31, 2022 1,530,910  
Weighted Average Exercise Price, Outstanding Beginning $ 5.32  
Weighted Average Exercise Price, Granted 2.36  
Weighted Average Exercise Price, Forfeited/Cancelled 25.99  
Weighted Average Exercise Price, Outstanding Ending 5.27 $ 5.32
Weighted Average Exercise Price, Vested and expected to vest at March 31, 2022 5.27  
Weighted Average Exercise Price, Exercisable at March 31, 2022 $ 6.04  
Weighted Average Remaining Contractual Term (Years), Outstanding 7 years 7 months 6 days 7 years 9 months 18 days
Weighted Average Remaining Contractual Term (Years), Vested and expected to vest at March 31, 2022 7 years 7 months 6 days  
Weighted Average Remaining Contractual Term (Years), Exercisable at March 31, 2022 6 years 6 months  
Aggregate Intrinsic Value, Outstanding Ending $ 1,375  
Aggregate Intrinsic Value, Vested and expected to vest at March 31, 2022 $ 1,375