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Segment Reporting
12 Months Ended
Dec. 31, 2025
Segment Reporting  
Segment Reporting

15. Segment Reporting

The Company operates and manages its business as one reportable operating segment, which is the business of developing a pathogen-specific bacteriophage therapeutics for the treatment of antibiotic-resistant and difficult-to-treat acute and chronic bacterial infections using its proprietary bacteriophage-based technology. The determination of a single business segment is consistent with the consolidated financial information regularly provided to the Company’s chief operating decision maker (“CODM”). The Company’s CODM is its Chief Executive Officer, who reviews financial information on an aggregate basis for purposes of assessing performance, making operating decisions, allocating resources and evaluating financial performance. The Company maintains 99.5% of its $12.2 million property and equipment, net, within the United States.

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The following table includes certain segment information for the years ended December 31, 2025 and 2024.

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Year Ended December 31, 

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​

2025

​

2024

Grant and award revenue

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$

4,904

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$

5,174

Operating expenses

​

​

​

​

​

​

Research and development expenses:

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​

​

​

​

​

AP-PA02: Non-Cystic Fibrosis Bronchiectasis

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​

114

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​

6,840

AP-PA02: Cystic Fibrosis

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​

33

​

​

236

AP-SA02: Bacteremia

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​

2,157

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​

4,177

AP-SA02: Prosthetic Joint Infection

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​

2

​

​

35

Expenses not allocated by projects

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​

2,696

​

​

2,408

Total external research and development expenses

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​

5,002

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​

13,696

Research and development personnel expenses

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​

9,199

​

​

10,764

Other research and development expenses

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​

9,516

​

​

9,966

Total research and development expenses

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​

23,717

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​

34,426

General and administrative expenses:

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​

​

​

​

​

General and administrative personnel expenses

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​

4,897

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​

4,935

Other general and administrative expenses

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​

7,512

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​

8,249

Total general and administrative expenses

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​

12,409

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​

13,184

Impairment expense

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​

5,412

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​

-

Total operating expenses

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​

41,538

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​

47,610

Operating loss

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(36,634)

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(42,436)

Other income (expense), net

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(137,165)

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23,520

Net loss

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$

(173,799)

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$

(18,916)

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