X0202 4 2006-03-31 1 0000920465 LA JOLLA PHARMACEUTICAL CO LJPC 0001237532 BENNETT BRUCE K JR 6455 NANCY RIDGE DRIVE SAN DIEGO CA 92121 0 1 0 0 VP of Manufacturing Common Stock 2006-03-31 5 J 0 E 185 3.06 A 12836 D Common Stock 431 I Held by wife Stock Option (right to buy) 2007-04-17 Common Stock 94795 94795 D Acquired pursuant to the Company?s Employee Stock Purchase Plan. Same as previously reported. Reporting only direct holdings, no transaction data is necessary. As of April 17, 2006, pursuant to the terms of the Amended and Restated Employment Agreement between the Company and the reporting person, dated February 23, 2006, all options owned by the reporting person (the "Options"), including 44,342 Options that became vested and exercisble on that date, were exercisable. The Options will expire and become unexercisable as of the close of business on April 17, 2007. /s/ Gail A. Sloan Attorney-in-fact for Bruce K. Bennett 2006-04-18