X0202 5 2004-12-31 0 0 0 0000920465 LA JOLLA PHARMACEUTICAL CO LJPC 0001237524 REILLY TEDDI 6455 NANCY RIDGE DRIVE SAN DIEGO CA 92121 0 1 0 0 VP of Human Resources Common Stock 2004-06-30 2004-06-30 5 J 0 1641 1.479 A 19046 D Common Stock 2004-09-30 2004-09-30 5 J 0 1388 1.479 A 20434 D Common Stock 2004-12-31 2004-12-31 5 J 0 1697 1.4195 A 22131 D Common Stock 22131 D Stock Option (right to buy) Common Stock 324500 324500 D Acquired pursuant to the Company?s Employee Stock Purchase Plan. Reporting only direct holdings, no transaction data is necessary /s/ Gail A. Sloan Attorney-in-fact for Theodora Reilly 2005-02-08