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Summary of Significant Accounting Policies (Details 2) (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2012
Dec. 31, 2011
Fair Value of Financial Instruments    
Financial assets carried at fair value, total $ 134,098 $ 112,030
Quoted Prices in Active Markets for Identical Assets (Level 1)
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 40 1,819
Quoted Prices in Active Markets for Identical Assets (Level 1) | Equity securities
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 40 1,819
Significant Other Observable Inputs (Level 2)
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 134,058 110,211
Significant Other Observable Inputs (Level 2) | Money market funds
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 1,033 4,469
Significant Other Observable Inputs (Level 2) | Commercial paper
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 36,539 31,394
Significant Other Observable Inputs (Level 2) | Corporate notes
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 11,353 1,435
Significant Other Observable Inputs (Level 2) | U.S. government and U.S government agency notes
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 85,133 72,913
Significant Unobservable Inputs (Level 3)
   
Fair Value of Financial Instruments    
Financial liabilities carried at fair value, total 17,252 29,164
Significant Unobservable Inputs (Level 3) | Warrant liability
   
Fair Value of Financial Instruments    
Financial liabilities carried at fair value, total 276 187
Significant Unobservable Inputs (Level 3) | Deferred acquisition consideration
   
Fair Value of Financial Instruments    
Financial liabilities carried at fair value, total 16,976 28,977
Total
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 134,098 112,030
Financial liabilities carried at fair value, total 17,252 29,164
Total | Warrant liability
   
Fair Value of Financial Instruments    
Financial liabilities carried at fair value, total 276 187
Total | Deferred acquisition consideration
   
Fair Value of Financial Instruments    
Financial liabilities carried at fair value, total 16,976 28,977
Total | Money market funds
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 1,033 4,469
Total | Commercial paper
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 36,539 31,394
Total | Corporate notes
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 11,353 1,435
Total | U.S. government and U.S government agency notes
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total 85,133 72,913
Total | Equity securities
   
Fair Value of Financial Instruments    
Financial assets carried at fair value, total $ 40 $ 1,819