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Consolidated Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Cash flows from operating activities:    
Net loss $ (13,676,117) $ (9,194,894)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 429,347 677,317
Accretion of convertible debt discount 14,023 0
Share-based compensation expense 241,860 303,894
Impairment of goodwill and amortizable intangible assets 3,201,546 0
Change in fair value of warrant liability (1,276,441) 0
Accretion of royalty liability 87,151 72,975
Changes in assets and liabilities:    
(Decrease) increase in accounts receivable (28,678) 1,021,997
Increase (decrease) in prepaid expenses and other current assets (79,749) 55,290
Increase (decrease) in other assets 1,111 (5,763)
Decrease in accounts payable and accrued expenses (367,181) (3,164,296)
Increase (decrease) in deferred revenue 1,357,711 (1,922,643)
Increase (decrease) in royalty liability 6,273 (193,623)
Decrease in other long-term liabilities (10,842) (21,482)
Net cash used in operating activities (10,099,986) (12,371,228)
Cash flows from investing activities:    
Acquisition of property and equipment (82,995) (95,239)
Net cash used in investing activities (82,995) (95,239)
Cash flows from financing activities:    
Net proceeds from issuance of common stock and warrants 8,206,729 14,457,789
Net proceeds from issuance of convertible debt and warrants 490,000 0
Proceeds from warrant exercises 0 121,862
Proceeds from employee stock purchase plan 42,508 99,495
Net cash provided by financing activities 8,739,237 14,679,146
Net (decrease) increase in cash and cash equivalents (1,443,744) 2,212,679
Cash and cash equivalents at beginning of period 1,777,414 2,120,102
Cash and cash equivalents at end of period 333,670 4,332,781
Cash paid during the period for:    
Interest $ 28,168 $ 60,209