X0306 4 2018-06-13 0 0001320414 SELECT MEDICAL HOLDINGS CORP SEM 0000918697 ORTENZIO ROBERT A C/O SELECT MEDICAL HOLDINGS CORPORATION 4714 GETTYSBURG ROAD MECHANICSBURG PA 17055 1 1 0 0 Exec. Chairman and Co-Founder Common Stock 2018-06-13 4 S 0 3800 18.50 D 6789748 D Common Stock 2018-06-14 4 S 0 17252 18.53 D 6772496 D Common Stock 800000 I By the Robert A. Ortenzio July 2017 GRAT Common Stock 31886 I By the Robert A. Ortenzio 2014 Trust for Bryan A. Ortenzio Common Stock 31886 I By the Robert A. Ortenzio 2014 Trust for Kevin M. Ortenzio Common Stock 31885 I By the Robert A. Ortenzio 2014 Trust for Madeline G. Ortenzio Common Stock 2750000 I By the Rocco A. Ortenzio Descendants Trust Common Stock 1300000 I By the Robert A. Ortenzio Descendants Trust These shares were sold pursuant to a Rule 10b5-1 trading plan adopted by Robert A. Ortenzio on November 14, 2017. The price reported in this column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $18.50 to $18.60, inclusive. The reporting person undertakes to provide to Select Medical Holdings Corporation, any security holder of Select Medical Holdings Corporation or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote to this Form 4. The reporting person beneficially owns the reported securities indirectly, but disclaims beneficial ownership to the reported securities except to the extent of his pecuniary interest therein. /s/ Michael E. Tarvin, as attorney-in-fact 2018-06-14