<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/nport" xmlns:com="http://www.sec.gov/edgar/common" xmlns:ncom="http://www.sec.gov/edgar/nportcommon" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0000918294</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000002083</seriesId>
        <classId>C000005448</classId>
        <classId>C000005449</classId>
      </seriesClassInfo>


    </filerInfo>
  </headerData>
  <formData>
    <genInfo>
      <regName>T. ROWE PRICE EQUITY SERIES, INC.</regName>
      <regFileNumber>811-07143</regFileNumber>
      <regCik>0000918294</regCik>
      <regLei>549300U8GAQGX2UFFV03</regLei>
      <regStreet1>1307 Point Street</regStreet1>
      <regCity>Baltimore</regCity>
      <regStateConditional regCountry="US" regState="US-MD"/>
      <regZipOrPostalCode>21231</regZipOrPostalCode>
      <regPhone>410-345-2000</regPhone>
      <seriesName>T. Rowe Price Health Sciences Portfolio</seriesName>
      <seriesId>S000002083</seriesId>
      <seriesLei>23LI9YJ7764IBT5W0K91</seriesLei>
      <repPdEnd>2026-12-31</repPdEnd>
      <repPdDate>2026-03-31</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>663518629.090000</totAssets>
      <totLiabs>894888.710000</totLiabs>
      <netAssets>662623740.380000</netAssets>
      <assetsAttrMiscSec>31857529.900000</assetsAttrMiscSec>
      <assetsInvested>0.000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.000000</amtPayAftOneYrOther>
      <delayDeliv>0.000000</delayDeliv>
      <standByCommit>260900.000000</standByCommit>
      <liquidPref>0.000000</liquidPref>
      <cshNotRptdInCorD>56189.870000</cshNotRptdInCorD>
      <curMetrics>
        <curMetric>
          <curCd>USD</curCd>
          <intrstRtRiskdv01 period10Yr="0.000000" period1Yr="0.000000" period30Yr="0.000000" period3Mon="0.000000" period5Yr="0.000000"/>
          <intrstRtRiskdv100 period10Yr="0.000000" period1Yr="0.000000" period30Yr="0.000000" period3Mon="0.000000" period5Yr="0.000000"/>
        </curMetric>
      </curMetrics>
      <creditSprdRiskInvstGrade period10Yr="0.000000" period1Yr="0.000000" period30Yr="0.000000" period3Mon="0.000000" period5Yr="0.000000"/>
      <creditSprdRiskNonInvstGrade period10Yr="0.000000" period1Yr="0.000000" period30Yr="0.000000" period3Mon="0.000000" period5Yr="0.000000"/>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
          <monthlyTotReturn classId="C000005448" rtn1="-0.990000" rtn2="0.670000" rtn3="-5.940000"/>
          <monthlyTotReturn classId="C000005449" rtn1="-1.020000" rtn2="0.670000" rtn3="-5.960000"/>
        </monthlyTotReturns>
        <othMon1 netRealizedGain="17417626.09" netUnrealizedAppr="-24371673.31"/>
        <othMon2 netRealizedGain="2555872.110000" netUnrealizedAppr="2243491.630000"/>
        <othMon3 netRealizedGain="1921536.730000" netUnrealizedAppr="-44296588.630000"/>
      </returnInfo>
      <mon1Flow redemption="22223300.720000" reinvestment="0.000000" sales="9045949.300000"/>
      <mon2Flow redemption="9464341.630000" reinvestment="0.000000" sales="6014571.040000"/>
      <mon3Flow redemption="10434521.760000" reinvestment="0.000000" sales="4829464.790000"/>


    </fundInfo>
    <invstOrSecs>
      <invstOrSec>
        <name>EXACT SCIENCES CMO MILESTONE PP</name>
        <lei>549300VM3X1FYD4N9Z14</lei>
        <title>- EXACT SCIENCES CMO MILESTONE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4Y8OHO5"/>
        </identifiers>
        <balance>167423.910000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ABBVIE INC</name>
        <lei>FR5LCKFTG8054YNNRU85</lei>
        <title>ABBVIE INC</title>
        <cusip>00287Y109</cusip>
        <identifiers>
          <isin value="US00287Y1091"/>
        </identifiers>
        <balance>87748.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>19084312.520000</valUSD>
        <pctVal>2.8801130049</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ABIVAX SA-ADR</name>
        <lei>969500D8TMNB184OJU95</lei>
        <title>ABIVAX SA</title>
        <cusip>00370M103</cusip>
        <identifiers>
          <isin value="US00370M1036"/>
        </identifiers>
        <balance>24954.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2778627.900000</valUSD>
        <pctVal>0.4193372091</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>FR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ADLAI NORTYE LTD-ADR</name>
        <lei>54930009TDXE4YQVKU60</lei>
        <title>ADLAI NORTYE LTD</title>
        <cusip>00704R109</cusip>
        <identifiers>
          <isin value="US00704R1095"/>
        </identifiers>
        <balance>13419.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>92859.480000</valUSD>
        <pctVal>0.0140139078</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AFFINIVAX AFX3772 MILESTONE EVENT PP</name>
        <lei>N/A</lei>
        <title>AFFINIVAX AFX3772 MILESTONE EVENT PP</title>
        <cusip>TC2HD0ET2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8072881"/>
        </identifiers>
        <balance>331975.800000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AFFINIVAX EXPENSE FUND PP</name>
        <lei>N/A</lei>
        <title>AFFINIVAX EXPENSE FUND PP</title>
        <cusip>TC929D1E2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8072884"/>
        </identifiers>
        <balance>562.150000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>522.290000</valUSD>
        <pctVal>0.0000788215</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AFFINIVAX NEXT GEN PROD MILESTON EVNT PP</name>
        <lei>N/A</lei>
        <title>AFFINIVAX NEXT GEN PROD MILESTON EVNT PP</title>
        <cusip>TC7BEY6E7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8072883"/>
        </identifiers>
        <balance>331975.800000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AGIOS PHARMACEUTICALS INC</name>
        <lei>529900ONJHY8EOGYT555</lei>
        <title>AGIOS PHARMACEUTICALS INC</title>
        <cusip>00847X104</cusip>
        <identifiers>
          <isin value="US00847X1046"/>
        </identifiers>
        <balance>4357.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>147397.310000</valUSD>
        <pctVal>0.0222444958</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AKTIS ONCOLOGY INC</name>
        <lei>N/A</lei>
        <title>AKTIS ONCOLOGY INC</title>
        <cusip>01021M104</cusip>
        <identifiers>
          <isin value="US01021M1045"/>
        </identifiers>
        <balance>20013.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>358032.570000</valUSD>
        <pctVal>0.0540325600</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALIGNMENT HEALTHCARE INC</name>
        <lei>N/A</lei>
        <title>ALIGNMENT HEALTHCARE INC</title>
        <cusip>01625V104</cusip>
        <identifiers>
          <isin value="US01625V1044"/>
        </identifiers>
        <balance>94456.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1664314.720000</valUSD>
        <pctVal>0.2511704031</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALLOGENE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ALLOGENE THERAPEUTICS INC</title>
        <cusip>019770106</cusip>
        <identifiers>
          <isin value="US0197701065"/>
        </identifiers>
        <balance>243268.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>593573.920000</valUSD>
        <pctVal>0.0895793320</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALNYLAM PHARMACEUTICALS INC</name>
        <lei>529900S3ZI14OWRJII50</lei>
        <title>ALNYLAM PHARMACEUTICALS INC</title>
        <cusip>02043Q107</cusip>
        <identifiers>
          <isin value="US02043Q1076"/>
        </identifiers>
        <balance>32630.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>10796288.100000</valUSD>
        <pctVal>1.6293240707</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALTO NEUROSCIENCE INC</name>
        <lei>N/A</lei>
        <title>ALTO NEUROSCIENCE INC</title>
        <cusip>02157Q109</cusip>
        <identifiers>
          <isin value="US02157Q1094"/>
        </identifiers>
        <balance>16400.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>368672.000000</valUSD>
        <pctVal>0.0556382118</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALUMIS INC</name>
        <lei>N/A</lei>
        <title>ALUMIS INC</title>
        <cusip>022307102</cusip>
        <identifiers>
          <isin value="US0223071020"/>
        </identifiers>
        <balance>72447.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1596007.410000</valUSD>
        <pctVal>0.2408617912</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AMGEN INC</name>
        <lei>62QBXGPJ34PQ72Z12S66</lei>
        <title>AMGEN INC</title>
        <cusip>031162100</cusip>
        <identifiers>
          <isin value="US0311621009"/>
        </identifiers>
        <balance>18569.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6533502.650000</valUSD>
        <pctVal>0.9860049153</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ANNEXON INC</name>
        <lei>N/A</lei>
        <title>ANNEXON INC</title>
        <cusip>03589W102</cusip>
        <identifiers>
          <isin value="US03589W1027"/>
        </identifiers>
        <balance>20477.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>113442.580000</valUSD>
        <pctVal>0.0171202106</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>APOGEE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>APOGEE THERAPEUTICS INC</title>
        <cusip>03770N101</cusip>
        <identifiers>
          <isin value="US03770N1019"/>
        </identifiers>
        <balance>34862.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2934334.540000</valUSD>
        <pctVal>0.4428357092</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARBOR BIO SERIES B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>ARBOR BIO SERIES B CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC89FRFR6"/>
        </identifiers>
        <balance>23994.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>127648.080000</valUSD>
        <pctVal>0.0192640366</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARBOR BIO SERIES C CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>ARBOR BIO SERIES C CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9POPC96"/>
        </identifiers>
        <balance>15714.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>83598.480000</valUSD>
        <pctVal>0.0126162820</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARGENX SE - ADR</name>
        <lei>7245009C5FZE6G9ODQ71</lei>
        <title>ARGENX SE</title>
        <cusip>04016X101</cusip>
        <identifiers>
          <isin value="US04016X1019"/>
        </identifiers>
        <balance>26555.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>19391788.750000</valUSD>
        <pctVal>2.9265158443</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARROWHEAD PHARMACEUTICALS INC</name>
        <lei>549300O3CSB8T7OZ3D66</lei>
        <title>ARROWHEAD PHARMACEUTICALS INC</title>
        <cusip>04280A100</cusip>
        <identifiers>
          <isin value="US04280A1007"/>
        </identifiers>
        <balance>18900.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1185030.000000</valUSD>
        <pctVal>0.1788390496</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARSENAL BIOSCIENCES SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>ARSENAL BIOSCIENCES SER C CVT PFD PP</title>
        <cusip>TC5YX3EI8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9828670"/>
        </identifiers>
        <balance>35023.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>650727.340000</valUSD>
        <pctVal>0.0982046523</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ASCENDIS PHARMA A/S - ADR</name>
        <lei>549300B66JN3W3J8GH73</lei>
        <title>ASCENDIS PHARMA A/S</title>
        <cusip>04351P101</cusip>
        <identifiers>
          <ticker value="ASND"/>
        </identifiers>
        <balance>41114.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9404005.220000</valUSD>
        <pctVal>1.4192074094</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DK</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ASTRAZENECA PLC</name>
        <lei>PY6ZZQWO2IZFZC3IOL08</lei>
        <title>ASTRAZENECA PLC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="GB0009895292"/>
        </identifiers>
        <balance>106710.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>21045346.200000</valUSD>
        <pctVal>3.1760628117</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ATRIUM THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ATRIUM THERAPEUTICS INC</title>
        <cusip>04965N104</cusip>
        <identifiers>
          <isin value="US04965N1046"/>
        </identifiers>
        <balance>41700.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>557529.000000</valUSD>
        <pctVal>0.0841396053</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AURA BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>AURA BIOSCIENCES INC</title>
        <cusip>05153U107</cusip>
        <identifiers>
          <isin value="US05153U1079"/>
        </identifiers>
        <balance>20070.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>134268.300000</valUSD>
        <pctVal>0.0202631285</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AVALYN PHARMA SER C-1 CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>AVALYN PHARMA SER C-1 CVT PFD STOCK PP</title>
        <cusip>TC6KYIDL7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9013945"/>
        </identifiers>
        <balance>388595.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>309438.200000</valUSD>
        <pctVal>0.0466989305</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AVALYN PHARMA SER D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>AVALYN PHARMA SER D CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC8YZ63P2"/>
        </identifiers>
        <balance>90102.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>71748.220000</valUSD>
        <pctVal>0.0108278976</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AXSOME THERAPEUTICS INC</name>
        <lei>549300EXGR0XLRJEIB95</lei>
        <title>AXSOME THERAPEUTICS INC</title>
        <cusip>05464T104</cusip>
        <identifiers>
          <isin value="US05464T1043"/>
        </identifiers>
        <balance>10053.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1699158.060000</valUSD>
        <pctVal>0.2564287931</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Aktis Oncology Inc. Lockup Shs PP</name>
        <lei>N/A</lei>
        <title>Aktis Oncology, Inc. IPO</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC59APEC2"/>
        </identifiers>
        <balance>35348.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>632375.720000</valUSD>
        <pctVal>0.0954351137</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BEAM THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>BEAM THERAPEUTICS INC</title>
        <cusip>07373V105</cusip>
        <identifiers>
          <isin value="US07373V1052"/>
        </identifiers>
        <balance>66698.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1589413.340000</valUSD>
        <pctVal>0.2398666458</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BELITE BIO INC - ADR</name>
        <lei>984500BD54036BOEAE79</lei>
        <title>BELITE BIO INC</title>
        <cusip>07782B104</cusip>
        <identifiers>
          <isin value="US07782B1044"/>
        </identifiers>
        <balance>12700.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2024888.000000</valUSD>
        <pctVal>0.3055863949</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BEONE MEDICINES LTD-ADR</name>
        <lei>549300JFUK6FRD5MH739</lei>
        <title>BEONE MEDICINES LTD</title>
        <cusip>07725L102</cusip>
        <identifiers>
          <isin value="US07725L1026"/>
        </identifiers>
        <balance>2980.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>884970.600000</valUSD>
        <pctVal>0.1335555227</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BEONE MEDICINES LTD</name>
        <lei>549300JFUK6FRD5MH739</lei>
        <title>BEONE MEDICINES LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="CH1391448177"/>
        </identifiers>
        <balance>355752.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="HKD" exchangeRt="7.841200"/>
        <valUSD>7980375.730000</valUSD>
        <pctVal>1.2043600680</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BETA BIONICS INC</name>
        <lei>N/A</lei>
        <title>BETA BIONICS INC</title>
        <cusip>08659B102</cusip>
        <identifiers>
          <isin value="US08659B1026"/>
        </identifiers>
        <balance>7112.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>71262.240000</valUSD>
        <pctVal>0.0107545558</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BICARA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>BICARA THERAPEUTICS INC</title>
        <cusip>055477103</cusip>
        <identifiers>
          <isin value="US0554771032"/>
        </identifiers>
        <balance>41599.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>827404.110000</valUSD>
        <pctVal>0.1248678639</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BICYCLE THERAPEUTICS PLC-ADR</name>
        <lei>213800XKUI6R7GKC3E43</lei>
        <title>BICYCLE THERAPEUTICS PLC</title>
        <cusip>088786108</cusip>
        <identifiers>
          <isin value="US0887861088"/>
        </identifiers>
        <balance>62846.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>291605.440000</valUSD>
        <pctVal>0.0440076958</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BILLIONTOONE INC CL A</name>
        <lei>N/A</lei>
        <title>BILLIONTOONE INC</title>
        <cusip>090168105</cusip>
        <identifiers>
          <isin value="US0901681058"/>
        </identifiers>
        <balance>16222.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1280564.680000</valUSD>
        <pctVal>0.1932566858</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BIO-RAD LABORATORIES-A</name>
        <lei>549300ZC1GPV35XYDK53</lei>
        <title>BIO-RAD LABORATORIES INC</title>
        <cusip>090572207</cusip>
        <identifiers>
          <isin value="US0905722072"/>
        </identifiers>
        <balance>3700.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1031375.000000</valUSD>
        <pctVal>0.1556501733</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BIOHAVEN LTD</name>
        <lei>N/A</lei>
        <title>BIOHAVEN LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="VGG1110E1079"/>
        </identifiers>
        <balance>78093.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>660666.780000</valUSD>
        <pctVal>0.0997046649</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>VG</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Blue Marlin Therapeutics Common Stock PP</name>
        <lei>N/A</lei>
        <title>BLUE MARLIN THERAPEUTICS COMMON STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1BZ3EG4"/>
        </identifiers>
        <balance>81.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8.100000</valUSD>
        <pctVal>0.0000012224</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BOSTON SCIENTIFIC CORP</name>
        <lei>Y6ZDD9FP4P8JSSJMW954</lei>
        <title>BOSTON SCIENTIFIC CORP</title>
        <cusip>101137107</cusip>
        <identifiers>
          <isin value="US1011371077"/>
        </identifiers>
        <balance>97805.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6137263.750000</valUSD>
        <pctVal>0.9262064390</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BridgeBio Oncology Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>BRIDGEBIO ONCOLOGY THERAPEUTICS INC</title>
        <cusip>107924102</cusip>
        <identifiers>
          <isin value="US1079241022"/>
        </identifiers>
        <balance>21253.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>190214.350000</valUSD>
        <pctVal>0.0287062383</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BRIDGEBIO PHARMA INC</name>
        <lei>54930028YG89VTY2J114</lei>
        <title>BRIDGEBIO PHARMA INC</title>
        <cusip>10806X102</cusip>
        <identifiers>
          <isin value="US10806X1028"/>
        </identifiers>
        <balance>53496.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3972612.960000</valUSD>
        <pctVal>0.5995277135</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BRIGHTSPRING HEALTH SERVICES</name>
        <lei>N/A</lei>
        <title>BRIGHTSPRING HEALTH SERVICES INC</title>
        <cusip>10950A106</cusip>
        <identifiers>
          <isin value="US10950A1060"/>
        </identifiers>
        <balance>154105.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6566414.050000</valUSD>
        <pctVal>0.9909717461</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cabaletta Bio Common WTS 09/26 PP</name>
        <lei>N/A</lei>
        <title>CABALETTA BIO COMMON WTS 09/26 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC04VICN9"/>
        </identifiers>
        <balance>93835.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>17828.650000</valUSD>
        <pctVal>0.0026906144</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CABALETTA BIO INC</name>
        <lei>N/A</lei>
        <title>CABALETTA BIO INC</title>
        <cusip>12674W109</cusip>
        <identifiers>
          <isin value="US12674W1099"/>
        </identifiers>
        <balance>44485.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>119664.650000</valUSD>
        <pctVal>0.0180592156</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CAPSULE CORP SERIES 1-D CVT PFD STOCK</name>
        <lei>N/A</lei>
        <title>CAPSULE CORP SERIES 1-D CVT PFD STOCK</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6MJWXO1"/>
        </identifiers>
        <balance>38140.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>38521.400000</valUSD>
        <pctVal>0.0058134651</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CAPSULE CORP SERIES E CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>CAPSULE CORP SERIES E CVT PFD STOCK PP</title>
        <cusip>TC0YJ3TD4</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8626377"/>
        </identifiers>
        <balance>40875.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>41283.750000</valUSD>
        <pctVal>0.0062303457</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CARDINAL HEALTH INC</name>
        <lei>CCU46N3GJMF4OK4N7U60</lei>
        <title>CARDINAL HEALTH INC</title>
        <cusip>14149Y108</cusip>
        <identifiers>
          <isin value="US14149Y1082"/>
        </identifiers>
        <balance>21571.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4558168.010000</valUSD>
        <pctVal>0.6878968760</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CARIS LIFE SCIENCES INC</name>
        <lei>549300LX5LO78M5VPY43</lei>
        <title>CARIS LIFE SCIENCES INC</title>
        <cusip>142152107</cusip>
        <identifiers>
          <isin value="US1421521071"/>
        </identifiers>
        <balance>116415.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2081500.200000</valUSD>
        <pctVal>0.3141300369</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CELCUITY INC</name>
        <lei>25490070W7UU7W2SEY87</lei>
        <title>CELCUITY INC</title>
        <cusip>15102K100</cusip>
        <identifiers>
          <isin value="US15102K1007"/>
        </identifiers>
        <balance>32571.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3717653.940000</valUSD>
        <pctVal>0.5610505198</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CELLANOME SERIES A CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>CELLANOME SERIES A CVT PFD STOCK PP</title>
        <cusip>TC13MXKE8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7298443"/>
        </identifiers>
        <balance>89839.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>781599.300000</valUSD>
        <pctVal>0.1179552214</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CELLDEX THERAPEUTICS INC</name>
        <lei>529900F018DMYWH38923</lei>
        <title>CELLDEX THERAPEUTICS INC</title>
        <cusip>15117B202</cusip>
        <identifiers>
          <isin value="US15117B2025"/>
        </identifiers>
        <balance>26430.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>838359.600000</valUSD>
        <pctVal>0.1265212139</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CENCORA INC</name>
        <lei>AI8GXW8LG5WK7E9UD086</lei>
        <title>CENCORA INC</title>
        <cusip>03073E105</cusip>
        <identifiers>
          <isin value="US03073E1055"/>
        </identifiers>
        <balance>11189.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3514912.460000</valUSD>
        <pctVal>0.5304537471</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CENTENE CORP</name>
        <lei>549300Z7JJ4TQSQGT333</lei>
        <title>CENTENE CORP</title>
        <cusip>15135B101</cusip>
        <identifiers>
          <isin value="US15135B1017"/>
        </identifiers>
        <balance>31861.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1043129.140000</valUSD>
        <pctVal>0.1574240518</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CENTESSA PHARMACEUTICALS-ADR</name>
        <lei>213800GIDAARDSKOI827</lei>
        <title>CENTESSA PHARMACEUTICALS PLC</title>
        <cusip>152309100</cusip>
        <identifiers>
          <isin value="US1523091007"/>
        </identifiers>
        <balance>83369.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3311416.680000</valUSD>
        <pctVal>0.4997431390</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CG ONCOLOGY INC</name>
        <lei>N/A</lei>
        <title>CG ONCOLOGY INC</title>
        <cusip>156944100</cusip>
        <identifiers>
          <isin value="US1569441009"/>
        </identifiers>
        <balance>69646.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4713641.280000</valUSD>
        <pctVal>0.7113601570</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CHARLES RIVER LABORATORIES</name>
        <lei>549300BSQ0R4UZ5KX287</lei>
        <title>CHARLES RIVER LABORATORIES INTERNATIONAL INC</title>
        <cusip>159864107</cusip>
        <identifiers>
          <isin value="US1598641074"/>
        </identifiers>
        <balance>4900.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>845250.000000</valUSD>
        <pctVal>0.1275610801</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NCHROMA BIO SER I CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>CHROMA MEDICINE SER I CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3N6OVC2"/>
        </identifiers>
        <balance>354997.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>354997.000000</valUSD>
        <pctVal>0.0535744463</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CHROMACODE INC PP</name>
        <lei>N/A</lei>
        <title>CHROMACODE INC PP</title>
        <cusip>TC43UPY99</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7573456"/>
        </identifiers>
        <balance>28.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>135.510000</valUSD>
        <pctVal>0.0000204505</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Chromacode INC SER AA CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>CHROMACODE INC SER AA CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7G6YEM8"/>
        </identifiers>
        <balance>2002.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9689.280000</valUSD>
        <pctVal>0.0014622597</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CHUGAI PHARMACEUTICAL CO LTD</name>
        <lei>529900T9LAII161DCN95</lei>
        <title>CHUGAI PHARMACEUTICAL CO LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="JP3519400000"/>
        </identifiers>
        <balance>69900.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="JPY" exchangeRt="158.705000"/>
        <valUSD>3854879.010000</valUSD>
        <pctVal>0.5817598699</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>JP</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CIGNA GROUP/THE</name>
        <lei>549300VIWYMSIGT1U456</lei>
        <title>CIGNA GROUP/THE</title>
        <cusip>125523100</cusip>
        <identifiers>
          <isin value="US1255231003"/>
        </identifiers>
        <balance>18644.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4973287.000000</valUSD>
        <pctVal>0.7505446450</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CLEAR LABS SER D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>CLEAR LABS SER D CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC5HJP6Y6"/>
        </identifiers>
        <balance>18600.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>57966.900000</valUSD>
        <pctVal>0.0087480868</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CLEAR LABS SERIES C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>CLEAR LABS SERIES C CVT PFD PP</title>
        <cusip>TC385IBS6</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6302485"/>
        </identifiers>
        <balance>171440.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>542401.870000</valUSD>
        <pctVal>0.0818566914</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CLEERLY SER C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>CLEERLY SER C CVT PFD STK PP</title>
        <cusip>TC1A1CZJ4</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7878855"/>
        </identifiers>
        <balance>26533.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>465654.150000</valUSD>
        <pctVal>0.0702742932</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Climb Bio Inc</name>
        <lei>N/A</lei>
        <title>CLIMB BIO INC</title>
        <cusip>28658R106</cusip>
        <identifiers>
          <isin value="US28658R1068"/>
        </identifiers>
        <balance>93200.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>638420.000000</valUSD>
        <pctVal>0.0963472875</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>COGENT BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>COGENT BIOSCIENCES INC</title>
        <cusip>19240Q201</cusip>
        <identifiers>
          <isin value="US19240Q2012"/>
        </identifiers>
        <balance>20611.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>793317.390000</valUSD>
        <pctVal>0.1197236594</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>COLOR HEALTH SR D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>COLOR HEALTH SER D CVT PFD STOCK PP</title>
        <cusip>TC1HL9RU8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5762425"/>
        </identifiers>
        <balance>13310.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>255418.900000</valUSD>
        <pctVal>0.0385465966</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>COLOR HEALTH SR D-1 CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>COLOR HEALTH SERIES D-1 CVT PFD STOCK PP</title>
        <cusip>TC3KSMZE0</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5763427"/>
        </identifiers>
        <balance>20165.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>271824.200000</valUSD>
        <pctVal>0.0410224058</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>COLOR HEALTH SERIES E CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>COLOR HEALTH SERIES E CVT PFD STOCK PP</title>
        <cusip>TC4SC4HB5</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6978860"/>
        </identifiers>
        <balance>1991.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>81631.000000</valUSD>
        <pctVal>0.0123193594</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CORVUS PHARMACEUTICALS INC</name>
        <lei>549300I3AVJ8F75NCX65</lei>
        <title>CORVUS PHARMACEUTICALS INC</title>
        <cusip>221015100</cusip>
        <identifiers>
          <isin value="US2210151005"/>
        </identifiers>
        <balance>48764.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>713417.320000</valUSD>
        <pctVal>0.1076655237</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CRESCENT BIOPHARMA INC</name>
        <lei>549300TZ84FFU2J2J459</lei>
        <title>CRESCENT BIOPHARMA INC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="KYG2545C1042"/>
        </identifiers>
        <balance>17631.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>323881.470000</valUSD>
        <pctVal>0.0488786396</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CRINETICS PHARMACEUTICALS IN</name>
        <lei>549300Q1CNFXK5P31D28</lei>
        <title>CRINETICS PHARMACEUTICALS INC</title>
        <cusip>22663K107</cusip>
        <identifiers>
          <isin value="US22663K1079"/>
        </identifiers>
        <balance>66707.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2422798.240000</valUSD>
        <pctVal>0.3656371018</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cullinan Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>CULLINAN THERAPEUTICS INC</title>
        <cusip>230031106</cusip>
        <identifiers>
          <isin value="US2300311063"/>
        </identifiers>
        <balance>42900.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>609609.000000</valUSD>
        <pctVal>0.0919992694</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CVS HEALTH CORP</name>
        <lei>549300EJG376EN5NQE29</lei>
        <title>CVS HEALTH CORP</title>
        <cusip>126650100</cusip>
        <identifiers>
          <isin value="US1266501006"/>
        </identifiers>
        <balance>79198.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5688000.360000</valUSD>
        <pctVal>0.8584057608</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CYTOKINETICS INC</name>
        <lei>549300BE5DY1HW7IHA64</lei>
        <title>CYTOKINETICS INC</title>
        <cusip>23282W605</cusip>
        <identifiers>
          <isin value="US23282W6057"/>
        </identifiers>
        <balance>40699.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2682471.090000</valUSD>
        <pctVal>0.4048256841</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DANAHER CORP</name>
        <lei>S4BKK9OTCEWQ3YHPFM11</lei>
        <title>DANAHER CORP</title>
        <cusip>235851102</cusip>
        <identifiers>
          <isin value="US2358511028"/>
        </identifiers>
        <balance>71673.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>13589200.800000</valUSD>
        <pctVal>2.0508170734</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Delfi Diagnostics CVT Prom Note PP</name>
        <lei>N/A</lei>
        <title>DELFI DIAGNOSTICS CVT PROM NOTE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC787QA79"/>
        </identifiers>
        <balance>78284.580000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>78284.580000</valUSD>
        <pctVal>0.0118143337</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2027-01-29</maturityDt>
          <couponKind>None</couponKind>
          <annualizedRt>0.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>DELFI DIAGNOSTICS INC PP</name>
              <title>DELFI DIAGNOSTICS INC PP</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DELFI DIAGNOSTICS SR A CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>DELFI DIAGNOSTICS SR A CVT PFD STOCK PP</title>
        <cusip>TC0LOSSE0</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5840456"/>
        </identifiers>
        <balance>154525.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>604192.750000</valUSD>
        <pctVal>0.0911818749</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DELFI DIAGNOSTICS SR B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>DELFI DIAGNOSTICS SR B CVT PFD STOCK PP</title>
        <cusip>TC7ZV25B2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7864785"/>
        </identifiers>
        <balance>84104.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>328846.640000</valUSD>
        <pctVal>0.0496279593</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DENALI THERAPEUTICS INC</name>
        <lei>549300ZTQ2HO18L3Q830</lei>
        <title>DENALI THERAPEUTICS INC</title>
        <cusip>24823R105</cusip>
        <identifiers>
          <isin value="US24823R1059"/>
        </identifiers>
        <balance>29350.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>563520.000000</valUSD>
        <pctVal>0.0850437383</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DIANTHUS THERAPEUTICS INC</name>
        <lei>549300Z3N6ODPCOFC890</lei>
        <title>DIANTHUS THERAPEUTICS INC</title>
        <cusip>252828108</cusip>
        <identifiers>
          <isin value="US2528281080"/>
        </identifiers>
        <balance>29534.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2478493.280000</valUSD>
        <pctVal>0.3740423304</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DISC MEDICINE INC</name>
        <lei>N/A</lei>
        <title>DISC MEDICINE INC</title>
        <cusip>254604101</cusip>
        <identifiers>
          <isin value="US2546041011"/>
        </identifiers>
        <balance>11423.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>730386.620000</valUSD>
        <pctVal>0.1102264491</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DNA SCRIPT SERIES C CVT PFD STOCK PP</name>
        <lei>8945001SCRZOZAUEFH64</lei>
        <title>DNA SCRIPT SERIES C CVT PFD STOCK PP</title>
        <cusip>TC3XW4UW2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7232456"/>
        </identifiers>
        <balance>1132.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.865164"/>
        <valUSD>117234.630000</valUSD>
        <pctVal>0.0176924886</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>FR</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Deepsight Tech Inc SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>Deepsight Tech Inc SER C CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7NEDRR5"/>
        </identifiers>
        <balance>20661.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>264301.710000</valUSD>
        <pctVal>0.0398871477</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EDWARDS LIFESCIENCES CORP</name>
        <lei>YA13X31F3V31L8TMPR58</lei>
        <title>EDWARDS LIFESCIENCES CORP</title>
        <cusip>28176E108</cusip>
        <identifiers>
          <isin value="US28176E1082"/>
        </identifiers>
        <balance>34286.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2745622.880000</valUSD>
        <pctVal>0.4143562497</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EIKON THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>EIKON THERAPEUTICS INC</title>
        <cusip>282564103</cusip>
        <identifiers>
          <isin value="US2825641036"/>
        </identifiers>
        <balance>20976.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>221926.080000</valUSD>
        <pctVal>0.0334920207</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELEMENT BIOSCIENCES SER C CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES SER C CVT PFD STOCK</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9YLUNV8"/>
        </identifiers>
        <balance>38785.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>266065.100000</valUSD>
        <pctVal>0.0401532701</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELEMENT BIOSCIENCES SER D CVT PFD PP</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES SER D CVT PFD PP</title>
        <cusip>TC3OATBR3</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9824045"/>
        </identifiers>
        <balance>13556.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>75235.800000</valUSD>
        <pctVal>0.0113542265</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELEMENT BIOSCIENCES SER D-1 CVT PFD PP</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES SER D-1 CVT PFD PP</title>
        <cusip>TC141T8S1</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9824046"/>
        </identifiers>
        <balance>13556.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>75235.800000</valUSD>
        <pctVal>0.0113542265</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELEVANCE HEALTH INC</name>
        <lei>8MYN82XMYQH89CTMTH67</lei>
        <title>ELEVANCE HEALTH INC</title>
        <cusip>036752103</cusip>
        <identifiers>
          <isin value="US0367521038"/>
        </identifiers>
        <balance>15076.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4413499.000000</valUSD>
        <pctVal>0.6660641222</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELI LILLY &amp; CO</name>
        <lei>FRDRIPF3EKNDJ2CQJL29</lei>
        <title>ELI LILLY &amp; CO</title>
        <cusip>532457108</cusip>
        <identifiers>
          <isin value="US5324571083"/>
        </identifiers>
        <balance>73591.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>67686794.070000</valUSD>
        <pctVal>10.2149666463</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENCOMPASS HEALTH CORP</name>
        <lei>549300FVRPM9DRQZRG64</lei>
        <title>ENCOMPASS HEALTH CORP</title>
        <cusip>29261A100</cusip>
        <identifiers>
          <isin value="US29261A1007"/>
        </identifiers>
        <balance>9603.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>928898.190000</valUSD>
        <pctVal>0.1401848641</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENDEAVOR BIO SERIES B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>END EAVOR BIO SERIES B CVT PFD STOCK PP</title>
        <cusip>TC0KH48I6</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7395452"/>
        </identifiers>
        <balance>84304.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>550049.880000</valUSD>
        <pctVal>0.0830108924</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENDEAVOR BIO SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>ENDEAVOR BIO SER C CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1MA9814"/>
        </identifiers>
        <balance>23627.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>154156.720000</valUSD>
        <pctVal>0.0232645936</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENLIVEN THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ENLIVEN THERAPEUTICS INC</title>
        <cusip>29337E102</cusip>
        <identifiers>
          <isin value="US29337E1029"/>
        </identifiers>
        <balance>3300.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>129360.000000</valUSD>
        <pctVal>0.0195223914</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENTRADA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ENTRADA THERAPEUTICS INC</title>
        <cusip>29384C108</cusip>
        <identifiers>
          <isin value="US29384C1080"/>
        </identifiers>
        <balance>20159.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>254406.580000</valUSD>
        <pctVal>0.0383938221</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ERASCA INC</name>
        <lei>N/A</lei>
        <title>ERASCA INC</title>
        <cusip>29479A108</cusip>
        <identifiers>
          <isin value="US29479A1088"/>
        </identifiers>
        <balance>76100.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1231298.000000</valUSD>
        <pctVal>0.1858215945</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EVOMMUNE INC</name>
        <lei>N/A</lei>
        <title>EVOMMUNE INC</title>
        <cusip>30054Y107</cusip>
        <identifiers>
          <isin value="US30054Y1073"/>
        </identifiers>
        <balance>16349.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>375863.510000</valUSD>
        <pctVal>0.0567235200</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EVOMMUNE INC PIPE PP</name>
        <lei>N/A</lei>
        <title>EVOMMUNE INC PIPE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4WYFYU6"/>
        </identifiers>
        <balance>7566.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>165245.220000</valUSD>
        <pctVal>0.0249380168</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EXACT SCIENCES FDA MILESTONE PP</name>
        <lei>549300VM3X1FYD4N9Z14</lei>
        <title>EXACT SCIENCES FDA MILESTONE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC81LO8E0"/>
        </identifiers>
        <balance>83711.960000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Eikon Therapeutics, Inc Lockup Shs PP</name>
        <lei>N/A</lei>
        <title>Eikon Therapeutics, Inc. IPO lockup</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC22B1342"/>
        </identifiers>
        <balance>16741.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>177119.780000</valUSD>
        <pctVal>0.0267300685</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MED INC SER D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>FOG PHARMA SER D CVT PFD STOCK PP</title>
        <cusip>TC2VY7UZ1</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8505067"/>
        </identifiers>
        <balance>27546.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>200190.560000</valUSD>
        <pctVal>0.0302118001</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MED INC SER E CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>FOG PHARMA SER E CVT PFD PP</title>
        <cusip>TC0O5RRO6</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9692804"/>
        </identifiers>
        <balance>29808.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>183748.440000</valUSD>
        <pctVal>0.0277304342</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MED INC SER C CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>FOG PHARMACEUTICALS SERIES C CVT PFD STOCK PP</title>
        <cusip>TC4W1BVL4</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5837441"/>
        </identifiers>
        <balance>19483.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>163682.530000</valUSD>
        <pctVal>0.0247021832</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME HOLDINGS SER B CVT PFD PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>FREENOME HOLDINGS SER B CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3E3G6L0"/>
        </identifiers>
        <balance>71397.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>208439.690000</valUSD>
        <pctVal>0.0314567193</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME HOLDINGS SER C CVT PFD PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>FREENOME HOLDINGS SER C CVT PFD PP</title>
        <cusip>TC87S2BF1</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5259505"/>
        </identifiers>
        <balance>41732.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>121834.320000</valUSD>
        <pctVal>0.0183866518</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME HOLDINGS SER D CVT PFD PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>FREENOME HOLDINGS SER D CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC55AWPR0"/>
        </identifiers>
        <balance>23669.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>69100.370000</valUSD>
        <pctVal>0.0104282968</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME HOLDINGS SER F CVT PFD PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>FREENOME HOLDINGS SER F CVT PFD PP</title>
        <cusip>TC17ZDYA2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9677139"/>
        </identifiers>
        <balance>8542.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>24937.910000</valUSD>
        <pctVal>0.0037635099</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Galvanize Therapeutics Ser C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>GALVANIZE THERAPEUTICS SER C CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3P6JXA0"/>
        </identifiers>
        <balance>742782.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>304540.620000</valUSD>
        <pctVal>0.0459598112</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENEDX HOLDINGS CORP WTS 7/26</name>
        <lei>N/A</lei>
        <title>GENEDX HOLDINGS CORP</title>
        <cusip>81663L119</cusip>
        <identifiers>
          <isin value="US81663L1199"/>
        </identifiers>
        <balance>11396.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>91.170000</valUSD>
        <pctVal>0.0000137589</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENERATE BIOMEDICINES INC</name>
        <lei>N/A</lei>
        <title>GENERATE BIOMEDICINES INC</title>
        <cusip>370920100</cusip>
        <identifiers>
          <isin value="US3709201004"/>
        </identifiers>
        <balance>16043.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>200537.500000</valUSD>
        <pctVal>0.0302641586</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENERATION BIO CO</name>
        <lei>N/A</lei>
        <title>GENERATION BIO CO</title>
        <cusip>000000000</cusip>
        <identifiers>
          <ticker value="GBIO"/>
        </identifiers>
        <balance>9145.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Genesis Molecular AI Ser A CVT PFD PP</name>
        <lei>N/A</lei>
        <title>GENESIS THERA SER A CVT PFD STOCK PP</title>
        <cusip>TC08XH789</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5657422"/>
        </identifiers>
        <balance>37471.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>191386.880000</valUSD>
        <pctVal>0.0288831909</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Genesis Molecular AI Ser B CVT PFD PP</name>
        <lei>N/A</lei>
        <title>GENESIS THERA SEV B CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2CU1CQ0"/>
        </identifiers>
        <balance>91103.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>465317.680000</valUSD>
        <pctVal>0.0702235147</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GILEAD SCIENCES INC</name>
        <lei>549300WTZWR07K8MNV44</lei>
        <title>GILEAD SCIENCES INC</title>
        <cusip>375558103</cusip>
        <identifiers>
          <isin value="US3755581036"/>
        </identifiers>
        <balance>124085.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>17293726.450000</valUSD>
        <pctVal>2.6098863346</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GINKGO BIOWORKS HOLDINGS INC</name>
        <lei>N/A</lei>
        <title>GINKGO BIOWORKS HOLDINGS INC</title>
        <cusip>37611X209</cusip>
        <identifiers>
          <isin value="US37611X2099"/>
        </identifiers>
        <balance>2281.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>13982.530000</valUSD>
        <pctVal>0.0021101764</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GUARDANT HEALTH INC</name>
        <lei>254900M8C3E5VC8BR186</lei>
        <title>GUARDANT HEALTH INC</title>
        <cusip>40131M109</cusip>
        <identifiers>
          <isin value="US40131M1099"/>
        </identifiers>
        <balance>65638.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6062982.060000</valUSD>
        <pctVal>0.9149962023</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GYROSCOPE THERAPEUTICS MLSTNE PYMT 1 PP</name>
        <lei>21380066POJ2YSHZAD73</lei>
        <title>GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 1 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7SL0DD0"/>
        </identifiers>
        <balance>253263.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GYROSCOPE THERAPEUTICS MLSTNE PYMT 2 PP</name>
        <lei>21380066POJ2YSHZAD73</lei>
        <title>GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 2 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2NYGIQ3"/>
        </identifiers>
        <balance>168785.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GYROSCOPE THERAPEUTICS MLSTNE PYMT 3 PP</name>
        <lei>21380066POJ2YSHZAD73</lei>
        <title>GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 3 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6SL2UQ9"/>
        </identifiers>
        <balance>168785.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GALVANIZE THERA SER C-1 CVT PFD PP</name>
        <lei>N/A</lei>
        <title>Galvanize Therapeutics Series C-1 CVT PFD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6AKD500"/>
        </identifiers>
        <balance>1656003.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>678961.230000</valUSD>
        <pctVal>0.1024655757</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Generate Biomedicines Inc Lockup Shs PP</name>
        <lei>N/A</lei>
        <title>Generate Biomedicines Inc lockup</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2LUK3K1"/>
        </identifiers>
        <balance>66811.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>835137.500000</valUSD>
        <pctVal>0.1260349500</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GINKGO BIOWORKS HLDS ERN OUT SHS 600 PP</name>
        <lei>N/A</lei>
        <title>Ginkgo Bioworks Holdings Earn Out Shares $15.00 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0XCAKJ3"/>
        </identifiers>
        <balance>242.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GINKGO BIOWORKS HLDS ERN OUT SHS 700 PP</name>
        <lei>N/A</lei>
        <title>Ginkgo Bioworks Holdings Earn Out Shares $17.50 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1WVCL58"/>
        </identifiers>
        <balance>242.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GINKGO BIOWORKS HLDS ERN OUT SH 800 PP</name>
        <lei>N/A</lei>
        <title>Ginkgo Bioworks Holdings Earn Out Shares $20.00 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC67CJNT0"/>
        </identifiers>
        <balance>242.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HCA HEALTHCARE INC</name>
        <lei>529900PH4ZGUH2MNEU89</lei>
        <title>HCA HEALTHCARE INC</title>
        <cusip>40412C101</cusip>
        <identifiers>
          <isin value="US40412C1018"/>
        </identifiers>
        <balance>12847.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6079714.280000</valUSD>
        <pctVal>0.9175213488</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HIMS &amp; HERS HEALTH INC</name>
        <lei>254900V041EIVTSB6D58</lei>
        <title>HIMS &amp; HERS HEALTH INC</title>
        <cusip>433000106</cusip>
        <identifiers>
          <isin value="US4330001060"/>
        </identifiers>
        <balance>6500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>134940.000000</valUSD>
        <pctVal>0.0203644982</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HONOR TECHNOLOGY SER D CVT PFD PP</name>
        <lei>N/A</lei>
        <title>HONOR TECHNOLOGY SER D CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9LOECG4"/>
        </identifiers>
        <balance>140829.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>42248.700000</valUSD>
        <pctVal>0.0063759714</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HONOR TECHNOLOGY SER E CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>HONOR TECHNOLOGY SER E CVT PFD STOCK PP</title>
        <cusip>TC2V4FT13</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6871504"/>
        </identifiers>
        <balance>94916.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>28474.800000</valUSD>
        <pctVal>0.0042972804</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IDEAYA BIOSCIENCES INC</name>
        <lei>549300ULW08F62IJML11</lei>
        <title>IDEAYA BIOSCIENCES INC</title>
        <cusip>45166A102</cusip>
        <identifiers>
          <isin value="US45166A1025"/>
        </identifiers>
        <balance>17571.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>585465.720000</valUSD>
        <pctVal>0.0883556813</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IDEXX LABORATORIES INC</name>
        <lei>OGMTXK0LUU1HKV2P0J84</lei>
        <title>IDEXX LABORATORIES INC</title>
        <cusip>45168D104</cusip>
        <identifiers>
          <isin value="US45168D1046"/>
        </identifiers>
        <balance>2621.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1472713.690000</valUSD>
        <pctVal>0.2222548937</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMATICS NV</name>
        <lei>984500DC691EZ96AF394</lei>
        <title>IMMATICS NV</title>
        <cusip>N44445109</cusip>
        <identifiers>
          <isin value="NL0015285941"/>
        </identifiers>
        <balance>38500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>378840.000000</valUSD>
        <pctVal>0.0571727176</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMIX BIOPHARMA INC</name>
        <lei>N/A</lei>
        <title>IMMIX BIOPHARMA INC</title>
        <cusip>45258H106</cusip>
        <identifiers>
          <isin value="US45258H1068"/>
        </identifiers>
        <balance>20000.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>182200.000000</valUSD>
        <pctVal>0.0274967510</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNEERING CORP - CLASS A</name>
        <lei>N/A</lei>
        <title>IMMUNEERING CORP</title>
        <cusip>45254E107</cusip>
        <identifiers>
          <isin value="US45254E1073"/>
        </identifiers>
        <balance>51854.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>273270.580000</valUSD>
        <pctVal>0.0412406866</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOCORE HOLDINGS PLC-ADR</name>
        <lei>213800IUE3DFS84BVN18</lei>
        <title>IMMUNOCORE HOLDINGS PLC</title>
        <cusip>45258D105</cusip>
        <identifiers>
          <isin value="US45258D1054"/>
        </identifiers>
        <balance>39016.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1176332.400000</valUSD>
        <pctVal>0.1775264495</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOCORE HOLDINGS CB 2.50% 2/30</name>
        <lei>213800IUE3DFS84BVN18</lei>
        <title>IMMUNOCORE HOLDINGS PLC</title>
        <cusip>45258DAB1</cusip>
        <identifiers>
          <isin value="US45258DAB10"/>
        </identifiers>
        <balance>739000.000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>666245.290000</valUSD>
        <pctVal>0.1005465469</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2030-02-01</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>2.5000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>IMMUNOCORE HOLDINGS PLC-ADR</name>
              <title>IMMUNOCORE HOLDINGS PLC-ADR</title>
              <curCd>USD</curCd>
              <identifiers>
                <isin value="US45258D1054"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="10.560100" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOME INC</name>
        <lei>N/A</lei>
        <title>IMMUNOME INC</title>
        <cusip>45257U108</cusip>
        <identifiers>
          <isin value="US45257U1088"/>
        </identifiers>
        <balance>107386.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2348531.820000</valUSD>
        <pctVal>0.3544291695</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOVANT INC</name>
        <lei>N/A</lei>
        <title>IMMUNOVANT INC</title>
        <cusip>45258J102</cusip>
        <identifiers>
          <isin value="US45258J1025"/>
        </identifiers>
        <balance>5100.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>126684.000000</valUSD>
        <pctVal>0.0191185423</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INCYTE CORP</name>
        <lei>549300Z4WN6JVZ3T4680</lei>
        <title>INCYTE CORP</title>
        <cusip>45337C102</cusip>
        <identifiers>
          <isin value="US45337C1027"/>
        </identifiers>
        <balance>28283.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2661995.960000</valUSD>
        <pctVal>0.4017356756</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSITRO SER B CVT PFD PP</name>
        <lei>N/A</lei>
        <title>INSITRO SER B CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC14F72Z4"/>
        </identifiers>
        <balance>39793.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>727857.740000</valUSD>
        <pctVal>0.1098448027</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSITRO SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>INSITRO SER C CVT PFD PP</title>
        <cusip>TC3HHHWL7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6095464"/>
        </identifiers>
        <balance>26282.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>480726.690000</valUSD>
        <pctVal>0.0725489687</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSMED INC</name>
        <lei>529900Q55QAG41CCAC11</lei>
        <title>INSMED INC</title>
        <cusip>457669307</cusip>
        <identifiers>
          <isin value="US4576693075"/>
        </identifiers>
        <balance>43093.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7046567.360000</valUSD>
        <pctVal>1.0634341830</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSPIRE MEDICAL SYSTEMS INC</name>
        <lei>549300XQQCQ7HCJKTW25</lei>
        <title>INSPIRE MEDICAL SYSTEMS INC</title>
        <cusip>457730109</cusip>
        <identifiers>
          <isin value="US4577301090"/>
        </identifiers>
        <balance>7200.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>371376.000000</valUSD>
        <pctVal>0.0560462865</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INTUITIVE SURGICAL INC</name>
        <lei>54930052SRG011710797</lei>
        <title>INTUITIVE SURGICAL INC</title>
        <cusip>46120E602</cusip>
        <identifiers>
          <isin value="US46120E6023"/>
        </identifiers>
        <balance>52937.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>24403427.630000</valUSD>
        <pctVal>3.6828483712</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IONIS PHARMACEUTICALS INC</name>
        <lei>549300SI4ZGLG0BLUZ92</lei>
        <title>IONIS PHARMACEUTICALS INC</title>
        <cusip>462222100</cusip>
        <identifiers>
          <isin value="US4622221004"/>
        </identifiers>
        <balance>55343.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4155705.870000</valUSD>
        <pctVal>0.6271592182</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IOVANCE BIOTHERAPEUTICS INC</name>
        <lei>2549002L8WT2ACU5Q878</lei>
        <title>IOVANCE BIOTHERAPEUTICS INC</title>
        <cusip>462260100</cusip>
        <identifiers>
          <isin value="US4622601007"/>
        </identifiers>
        <balance>127849.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>448749.990000</valUSD>
        <pctVal>0.0677231983</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IQVIA HOLDINGS INC</name>
        <lei>549300W3R20NM4KQPH86</lei>
        <title>IQVIA HOLDINGS INC</title>
        <cusip>46266C105</cusip>
        <identifiers>
          <isin value="US46266C1053"/>
        </identifiers>
        <balance>13072.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2229298.880000</valUSD>
        <pctVal>0.3364351055</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>JANUX THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>JANUX THERAPEUTICS INC</title>
        <cusip>47103J105</cusip>
        <identifiers>
          <isin value="US47103J1051"/>
        </identifiers>
        <balance>2205.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>30649.500000</valUSD>
        <pctVal>0.0046254757</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>JOHNSON &amp; JOHNSON</name>
        <lei>549300G0CFPGEF6X2043</lei>
        <title>JOHNSON &amp; JOHNSON</title>
        <cusip>478160104</cusip>
        <identifiers>
          <isin value="US4781601046"/>
        </identifiers>
        <balance>66600.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>16279704.000000</valUSD>
        <pctVal>2.4568549250</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kailera Therapeutics SER B CVT PFD PP</name>
        <lei>N/A</lei>
        <title>KAILERA THERAPEUTICS SER B CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7TQ7JB6"/>
        </identifiers>
        <balance>36605.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>512470.000000</valUSD>
        <pctVal>0.0773395169</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KARDIUM INC SER D-5 CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>KARDIUM INC SER D-5 CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2GK4KE4"/>
        </identifiers>
        <balance>403778.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>330774.940000</valUSD>
        <pctVal>0.0499189691</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kardium Inc Series D-8 CVT PFD Stock PP</name>
        <lei>N/A</lei>
        <title>KARDIUM INC SERIES D-8 CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9ZSWM29"/>
        </identifiers>
        <balance>373263.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>241590.740000</valUSD>
        <pctVal>0.0364597169</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kardium Inc Ser D-6 CVT Pfd Stock PP</name>
        <lei>N/A</lei>
        <title>KARDIUM SERIES D6 CVT PFD STOCK PP</title>
        <cusip>TC0GUUWU8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5832431"/>
        </identifiers>
        <balance>556501.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>460448.930000</valUSD>
        <pctVal>0.0694887463</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kartos Therapeutics CVT Prom Note PP</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS CVT PROM NOTE PP</title>
        <cusip>TC9IB1JR2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="10766328"/>
        </identifiers>
        <balance>44800.980000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>44800.980000</valUSD>
        <pctVal>0.0067611492</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2027-03-04</maturityDt>
          <couponKind>None</couponKind>
          <annualizedRt>0.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>KARTOS THERAPEUTICS INC PP</name>
              <title>KARTOS THERAPEUTICS INC PP</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KARTOS THERAPEUTICS SR C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS SR C CVT PFD STK PP</title>
        <cusip>TC1HQTAC7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8997784"/>
        </identifiers>
        <balance>85928.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>485750.980000</valUSD>
        <pctVal>0.0733072105</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kartos Therapeutics SR D CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS SR D CVT PFD STK PP</title>
        <cusip>TC82Z0AE2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="10300524"/>
        </identifiers>
        <balance>27086.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>153117.160000</valUSD>
        <pctVal>0.0231077081</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KESTRA MEDICAL TECHNOLOGIES</name>
        <lei>N/A</lei>
        <title>KESTRA MEDICAL TECHNOLOGIES LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="BMG524411052"/>
        </identifiers>
        <balance>48776.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>972105.680000</valUSD>
        <pctVal>0.1467055315</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KODIAK SCIENCES INC</name>
        <lei>254900IXI5NI8C9OQE24</lei>
        <title>KODIAK SCIENCES INC</title>
        <cusip>50015M109</cusip>
        <identifiers>
          <isin value="US50015M1099"/>
        </identifiers>
        <balance>56241.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2143906.920000</valUSD>
        <pctVal>0.3235481600</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KRYSTAL BIOTECH INC</name>
        <lei>549300YONUY68210OE41</lei>
        <title>KRYSTAL BIOTECH INC</title>
        <cusip>501147102</cusip>
        <identifiers>
          <isin value="US5011471027"/>
        </identifiers>
        <balance>16983.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4387048.560000</valUSD>
        <pctVal>0.6620723486</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KYMERA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KYMERA THERAPEUTICS INC</title>
        <cusip>501575104</cusip>
        <identifiers>
          <isin value="US5015751044"/>
        </identifiers>
        <balance>61124.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5091017.960000</valUSD>
        <pctVal>0.7683120374</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KYVERNA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KYVERNA THERAPEUTICS INC</title>
        <cusip>501976104</cusip>
        <identifiers>
          <isin value="US5019761049"/>
        </identifiers>
        <balance>80673.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>696207.990000</valUSD>
        <pctVal>0.1050683740</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kardium Inc Series D-7 CVT PFD Stock PP</name>
        <lei>N/A</lei>
        <title>Kardium, Inc. Series D-7 CVT Pfd Stock</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7NVVSV6"/>
        </identifiers>
        <balance>584117.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>378063.890000</valUSD>
        <pctVal>0.0570555908</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>LANTHEUS HOLDINGS INC</name>
        <lei>5299005HUB5IOJGO7S39</lei>
        <title>LANTHEUS HOLDINGS INC</title>
        <cusip>516544103</cusip>
        <identifiers>
          <isin value="US5165441032"/>
        </identifiers>
        <balance>7500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>568875.000000</valUSD>
        <pctVal>0.0858518893</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SAIL BIOMEDICINES SER B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>LARONDE SERIES B CVT PFD STOCK PP</title>
        <cusip>TC14DLDG5</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6589904"/>
        </identifiers>
        <balance>52537.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>75653.280000</valUSD>
        <pctVal>0.0114172305</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>LENZ THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>LENZ THERAPEUTICS INC</title>
        <cusip>52635N103</cusip>
        <identifiers>
          <isin value="US52635N1037"/>
        </identifiers>
        <balance>10126.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>92652.900000</valUSD>
        <pctVal>0.0139827317</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>LIQUIDIA CORP</name>
        <lei>N/A</lei>
        <title>LIQUIDIA CORP</title>
        <cusip>53635D202</cusip>
        <identifiers>
          <isin value="US53635D2027"/>
        </identifiers>
        <balance>15854.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>598329.960000</valUSD>
        <pctVal>0.0902970907</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>LUMICKS TECH SER D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>LUMICKS TECH SER D CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4O9ZGR5"/>
        </identifiers>
        <balance>221.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>119114.580000</valUSD>
        <pctVal>0.0179762017</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MADRIGAL PHARMACEUTICALS INC</name>
        <lei>549300CHIMT2EUSNJB60</lei>
        <title>MADRIGAL PHARMACEUTICALS INC</title>
        <cusip>558868105</cusip>
        <identifiers>
          <isin value="US5588681057"/>
        </identifiers>
        <balance>4568.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2391210.960000</valUSD>
        <pctVal>0.3608701008</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MBX BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>MBX BIOSCIENCES INC</title>
        <cusip>55287L101</cusip>
        <identifiers>
          <isin value="US55287L1017"/>
        </identifiers>
        <balance>44028.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1314235.800000</valUSD>
        <pctVal>0.1983381699</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MCKESSON CORP</name>
        <lei>549300WZWOM80UCFSF54</lei>
        <title>MCKESSON CORP</title>
        <cusip>58155Q103</cusip>
        <identifiers>
          <isin value="US58155Q1031"/>
        </identifiers>
        <balance>1545.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1336981.200000</valUSD>
        <pctVal>0.2017707967</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MEDIWOUND LTD</name>
        <lei>549300LJKCS74GRYKF90</lei>
        <title>MEDIWOUND LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="IL0011316309"/>
        </identifiers>
        <balance>3812.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>61411.320000</valUSD>
        <pctVal>0.0092679022</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MEDPACE HOLDINGS INC</name>
        <lei>549300H8TYEUVTW14A54</lei>
        <title>MEDPACE HOLDINGS INC</title>
        <cusip>58506Q109</cusip>
        <identifiers>
          <isin value="US58506Q1094"/>
        </identifiers>
        <balance>1400.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>672266.000000</valUSD>
        <pctVal>0.1014551636</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MERCK &amp; CO. INC.</name>
        <lei>4YV9Y5M8S0BRK1RP0397</lei>
        <title>MERCK &amp; CO INC</title>
        <cusip>58933Y105</cusip>
        <identifiers>
          <isin value="US58933Y1055"/>
        </identifiers>
        <balance>190448.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>22908989.920000</valUSD>
        <pctVal>3.4573149925</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mirum Pharma 6 month Lockup Shs PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>MIRUM PHARMA 6 MONTH LOCKUP SHS PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7WKV832"/>
        </identifiers>
        <balance>5416.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>475313.580000</valUSD>
        <pctVal>0.0717320481</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mirum Pharma 9 month Lockup Shs PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>MIRUM PHARMA 9 MONTH LOCKUP SHS PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC11DIJJ6"/>
        </identifiers>
        <balance>5417.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>475401.340000</valUSD>
        <pctVal>0.0717452924</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MIRUM PHARMACEUTICALS INC</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>MIRUM PHARMACEUTICALS INC</title>
        <cusip>604749101</cusip>
        <identifiers>
          <isin value="US6047491013"/>
        </identifiers>
        <balance>14079.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1300618.020000</valUSD>
        <pctVal>0.1962830398</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MODERNA THERAPEUTICS INC</name>
        <lei>549300EI6OKH5K5Q2G38</lei>
        <title>MODERNA INC</title>
        <cusip>60770K107</cusip>
        <identifiers>
          <isin value="US60770K1079"/>
        </identifiers>
        <balance>32300.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1640840.000000</valUSD>
        <pctVal>0.2476277109</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MOLINA HEALTHCARE INC</name>
        <lei>549300NQQCEQ46YHZ591</lei>
        <title>MOLINA HEALTHCARE INC</title>
        <cusip>60855R100</cusip>
        <identifiers>
          <isin value="US60855R1005"/>
        </identifiers>
        <balance>5556.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>740614.800000</valUSD>
        <pctVal>0.1117700370</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MONOPAR THERAPEUTICS INC</name>
        <lei>549300QJFAI7L6YHKG83</lei>
        <title>MONOPAR THERAPEUTICS INC</title>
        <cusip>61023L207</cusip>
        <identifiers>
          <isin value="US61023L2079"/>
        </identifiers>
        <balance>2185.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>119716.150000</valUSD>
        <pctVal>0.0180669877</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MONTE ROSA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>MONTE ROSA THERAPEUTICS INC</title>
        <cusip>61225M102</cusip>
        <identifiers>
          <isin value="US61225M1027"/>
        </identifiers>
        <balance>111845.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1839850.250000</valUSD>
        <pctVal>0.2776613843</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MOONLAKE IMMUNOTHERAPEUTICS</name>
        <lei>N/A</lei>
        <title>MOONLAKE IMMUNOTHERAPEUTICS</title>
        <cusip>61559X104</cusip>
        <identifiers>
          <isin value="KY61559X1045"/>
        </identifiers>
        <balance>54070.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1007864.800000</valUSD>
        <pctVal>0.1521021265</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MANUS BIO INC SERIES ONE-6 CVT PFD PP</name>
        <lei>N/A</lei>
        <title>Manus Bio, Inc Series One-6</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7PW0OO8"/>
        </identifiers>
        <balance>54498.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>163494.000000</valUSD>
        <pctVal>0.0246737311</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mirum Pharma Escrow Expense Fund PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>Mirum Pharma Escrow Expense Fund PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC40YLCB9"/>
        </identifiers>
        <balance>2317.840000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2201.950000</valUSD>
        <pctVal>0.0003323077</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mirum Pharma Escrow Indemnity PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>Mirum Pharma Escrow Indemnity PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0LICQW4"/>
        </identifiers>
        <balance>57482.650000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>54608.520000</valUSD>
        <pctVal>0.0082412562</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mirum Pharma Escrow Working Capital PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>Mirum Pharma Escrow Working Capital PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC81BERT9"/>
        </identifiers>
        <balance>2317.840000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2201.950000</valUSD>
        <pctVal>0.0003323077</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mirum Pharma Indemnity Holdback Shs PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>Mirum Pharma Indemnity Holdback Shs PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7AKG445"/>
        </identifiers>
        <balance>1210.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>106190.810000</valUSD>
        <pctVal>0.0160258082</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mirum Pharma Milestone $500 mil PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>Mirum Pharma Milestone $500 mil PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9TUEUN5"/>
        </identifiers>
        <balance>165208.300000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mirum Pharma Milestone $750 mil PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>Mirum Pharma Milestone $750 mil PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC75UI2P6"/>
        </identifiers>
        <balance>275347.170000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NATERA INC</name>
        <lei>529900CQ3OZ0A0VYVU59</lei>
        <title>NATERA INC</title>
        <cusip>632307104</cusip>
        <identifiers>
          <isin value="US6323071042"/>
        </identifiers>
        <balance>35183.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7036248.170000</valUSD>
        <pctVal>1.0618768603</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NATIONAL RESILIENCE SR B CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>NATIONAL RESILIENCE SER B CVT PFD STOCK</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1NJ9YP1"/>
        </identifiers>
        <balance>54252.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1186491.240000</valUSD>
        <pctVal>0.1790595730</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NATIONAL RESILIENCE SR C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>NATIONAL RESILIENCE SER C CVT PFD STOCK</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1STY873"/>
        </identifiers>
        <balance>19224.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>420428.880000</valUSD>
        <pctVal>0.0634491121</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NOVO-NORDISK A/S-SPONS ADR</name>
        <lei>549300DAQ1CVT6CXN342</lei>
        <title>NOVO NORDISK A/S</title>
        <cusip>670100205</cusip>
        <identifiers>
          <isin value="US6701002056"/>
        </identifiers>
        <balance>27816.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1022238.000000</valUSD>
        <pctVal>0.1542712610</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DK</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NURIX THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>NURIX THERAPEUTICS INC</title>
        <cusip>67080M103</cusip>
        <identifiers>
          <isin value="US67080M1036"/>
        </identifiers>
        <balance>73686.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1142133.000000</valUSD>
        <pctVal>0.1723652399</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NUTCRACKER THERA SER C CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>NUTCRACKER THERA SER C CVT PFD STOCK PP</title>
        <cusip>TC3WVBUQ2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6730480"/>
        </identifiers>
        <balance>46567.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NUVALENT INC-A</name>
        <lei>N/A</lei>
        <title>NUVALENT INC</title>
        <cusip>670703107</cusip>
        <identifiers>
          <isin value="US6707031075"/>
        </identifiers>
        <balance>28970.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2967976.500000</valUSD>
        <pctVal>0.4479127926</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NUVATION BIO INC</name>
        <lei>N/A</lei>
        <title>NUVATION BIO INC</title>
        <cusip>67080N101</cusip>
        <identifiers>
          <isin value="US67080N1019"/>
        </identifiers>
        <balance>11423.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>49004.670000</valUSD>
        <pctVal>0.0073955500</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>OBSIDIAN THERAPEUTIC SR C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>OBSIDIAN THERAPEUTICS SR C CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0AIZJ47"/>
        </identifiers>
        <balance>222385.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>422064.490000</valUSD>
        <pctVal>0.0636959505</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>OCULAR THERAPEUTIX INC</name>
        <lei>529900ABAWFXOHSIHG03</lei>
        <title>OCULAR THERAPEUTIX INC</title>
        <cusip>67576A100</cusip>
        <identifiers>
          <isin value="US67576A1007"/>
        </identifiers>
        <balance>89400.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>757218.000000</valUSD>
        <pctVal>0.1142757124</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Odyssey Therapeutics SER D CVT Pfd Stk PP</name>
        <lei>N/A</lei>
        <title>ODYSSEY THERAPEUTICS SER D CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9221RK3"/>
        </identifiers>
        <balance>24579.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>36990.660000</valUSD>
        <pctVal>0.0055824532</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ODYSSEY THERAPEUTICS SR B CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>ODYSSEY THERAPEUTICS SR B CVT PFD STK PP</title>
        <cusip>TC4CBMMO7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7849359"/>
        </identifiers>
        <balance>50567.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>79895.860000</valUSD>
        <pctVal>0.0120575004</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ODYSSEY THERAPEUTICS SR C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>ODYSSEY THERAPEUTICS SR C CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0AM4J17"/>
        </identifiers>
        <balance>4902.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7377.360000</valUSD>
        <pctVal>0.0011133558</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Odyssey Therapeutics Warrants 6/32 WRT PP</name>
        <lei>N/A</lei>
        <title>ODYSSEY THERAPEUTICS WARRANTS 6/32 WRT PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2DVYMO9"/>
        </identifiers>
        <balance>7373.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>OLEMA PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>OLEMA PHARMACEUTICALS INC</title>
        <cusip>68062P106</cusip>
        <identifiers>
          <isin value="US68062P1066"/>
        </identifiers>
        <balance>40697.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>606792.270000</valUSD>
        <pctVal>0.0915741820</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ORIC PHARMACEUTICALS INC</name>
        <lei>54930033FJRNEYBW0L25</lei>
        <title>ORIC PHARMACEUTICALS INC</title>
        <cusip>68622P109</cusip>
        <identifiers>
          <isin value="US68622P1093"/>
        </identifiers>
        <balance>110459.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1399515.530000</valUSD>
        <pctVal>0.2112081781</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ORUKA THERAPEUTICS INC</name>
        <lei>529900TG7O4ESUDMGI54</lei>
        <title>ORUKA THERAPEUTICS INC</title>
        <cusip>687604108</cusip>
        <identifiers>
          <isin value="US6876041087"/>
        </identifiers>
        <balance>28926.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1418820.300000</valUSD>
        <pctVal>0.2141215615</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PALVELLA THERAPEUTICS INC</name>
        <lei>254900AJDH8PAOOI5T33</lei>
        <title>PALVELLA THERAPEUTICS INC</title>
        <cusip>697947109</cusip>
        <identifiers>
          <isin value="US6979471090"/>
        </identifiers>
        <balance>9427.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1175075.550000</valUSD>
        <pctVal>0.1773367717</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MED INC SER F CVT PFD PP</name>
        <lei>N/A</lei>
        <title>PARABILIS MED INC SER F CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4H1NKL3"/>
        </identifiers>
        <balance>60045.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>370141.400000</valUSD>
        <pctVal>0.0558599666</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PAX LABS CLASS A COMMON PP</name>
        <lei>549300FKJA0AEKUHVG68</lei>
        <title>PAX LABS CLASS A COMMON PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6N68XA6"/>
        </identifiers>
        <balance>385684.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>119562.040000</valUSD>
        <pctVal>0.0180437302</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PHARVARIS NV</name>
        <lei>9845003BE146D3B75D32</lei>
        <title>PHARVARIS NV</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="NL00150005Y4"/>
        </identifiers>
        <balance>20584.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>581498.000000</valUSD>
        <pctVal>0.0877568920</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PRAXIS PRECISION MEDICINES I</name>
        <lei>N/A</lei>
        <title>PRAXIS PRECISION MEDICINES INC</title>
        <cusip>74006W207</cusip>
        <identifiers>
          <isin value="US74006W2070"/>
        </identifiers>
        <balance>11574.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3729027.060000</valUSD>
        <pctVal>0.5627668966</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROCEPT BIOROBOTICS CORP</name>
        <lei>N/A</lei>
        <title>PROCEPT BIOROBOTICS CORP</title>
        <cusip>74276L105</cusip>
        <identifiers>
          <isin value="US74276L1052"/>
        </identifiers>
        <balance>17941.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>448704.410000</valUSD>
        <pctVal>0.0677163196</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROFOUNDBIO ESCROW FUND PAYMENT PP</name>
        <lei>N/A</lei>
        <title>PROFOUNBIO ESCROW FUND PAYMENT</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7U0XRJ8"/>
        </identifiers>
        <balance>33627.010000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>31945.660000</valUSD>
        <pctVal>0.0048210859</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROFOUNDBIO EXPENSE FUND PAYMENT PP</name>
        <lei>N/A</lei>
        <title>PROFOUNDBIO EXPENSE FUND PYMT</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC23PZLJ7"/>
        </identifiers>
        <balance>112.090000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>22.420000</valUSD>
        <pctVal>0.0000033835</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROGNOMIQ INC CL A Common  PP</name>
        <lei>N/A</lei>
        <title>PROGNOMIQ INC PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1WY4OI2"/>
        </identifiers>
        <balance>27338.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4100.700000</valUSD>
        <pctVal>0.0006188580</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROTAGONIST THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>PROTAGONIST THERAPEUTICS INC</title>
        <cusip>74366E102</cusip>
        <identifiers>
          <isin value="US74366E1029"/>
        </identifiers>
        <balance>69663.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7342480.200000</valUSD>
        <pctVal>1.1080919310</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RADNET INC</name>
        <lei>529900RECG94V2IZJ970</lei>
        <title>RADNET INC</title>
        <cusip>750491102</cusip>
        <identifiers>
          <isin value="US7504911022"/>
        </identifiers>
        <balance>1116.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>62373.240000</valUSD>
        <pctVal>0.0094130705</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RAPPORT THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>RAPPORT THERAPEUTICS INC</title>
        <cusip>75383L102</cusip>
        <identifiers>
          <isin value="US75383L1026"/>
        </identifiers>
        <balance>37225.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1164770.250000</valUSD>
        <pctVal>0.1757815452</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Reflexion Med CVT Note issued 082725 PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MED CVT NOTE ISSUED 082725 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3F1Y6H9"/>
        </identifiers>
        <balance>12142.500000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>32784.750000</valUSD>
        <pctVal>0.0049477174</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2026-07-11</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>15.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>REFLEXION MEDICAL INC</name>
              <title>REFLEXION MEDICAL INC</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Reflexion Med CVT Note issued 081325 PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MED CVT PROM NOTE 081325 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC09D0VT3"/>
        </identifiers>
        <balance>12142.500000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>33027.600000</valUSD>
        <pctVal>0.0049843671</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2026-07-11</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>15.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>REFLEXION MEDICAL INC</name>
              <title>REFLEXION MEDICAL INC</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Reflexion Med CVT Note issued 072525 PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL CVT PROM NOTE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4FJHLV8"/>
        </identifiers>
        <balance>12142.500000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>33270.450000</valUSD>
        <pctVal>0.0050210169</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2026-08-11</maturityDt>
          <couponKind>None</couponKind>
          <annualizedRt>0.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>REFLEXION MEDICAL INC PP</name>
              <title>REFLEXION MEDICAL INC PP</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REFLEXION MEDICAL INC CVT PFD SR D-X PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL INC CVT</title>
        <cusip>TC70GKL85</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5147983"/>
        </identifiers>
        <balance>51079.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>66.400000</valUSD>
        <pctVal>0.0000100208</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REFLEXION MEDICAL INC CVT PFD SR C-X PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL INC CVT PFD SR C PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <ticker value="TC37G1B6"/>
        </identifiers>
        <balance>150708.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>195.920000</valUSD>
        <pctVal>0.0000295673</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REFLEXION MEDICAL SER F CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL INC PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC58LDJM2"/>
        </identifiers>
        <balance>83280.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>83.280000</valUSD>
        <pctVal>0.0000125682</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REFLEXION MEDICAL INC CVT PFD SR E-X PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL INC SR E CVT PFD PP</title>
        <cusip>TC9L8ZXJ6</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7579526"/>
        </identifiers>
        <balance>83857.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>117.400000</valUSD>
        <pctVal>0.0000177174</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REGENERON PHARMACEUTICALS</name>
        <lei>549300RCBFWIRX3HYQ56</lei>
        <title>REGENERON PHARMACEUTICALS INC</title>
        <cusip>75886F107</cusip>
        <identifiers>
          <isin value="US75886F1075"/>
        </identifiers>
        <balance>23001.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>17771492.640000</valUSD>
        <pctVal>2.6819885188</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RELAY THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>RELAY THERAPEUTICS INC</title>
        <cusip>75943R102</cusip>
        <identifiers>
          <isin value="US75943R1023"/>
        </identifiers>
        <balance>80419.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>800169.050000</valUSD>
        <pctVal>0.1207576791</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REPLIGEN CORP</name>
        <lei>54930006QJ0T5AUO1E71</lei>
        <title>REPLIGEN CORP</title>
        <cusip>759916109</cusip>
        <identifiers>
          <isin value="US7599161095"/>
        </identifiers>
        <balance>6705.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>789983.100000</valUSD>
        <pctVal>0.1192204643</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REPLIMUNE GROUP INC</name>
        <lei>549300AY704NEIRC4K64</lei>
        <title>REPLIMUNE GROUP INC</title>
        <cusip>76029N106</cusip>
        <identifiers>
          <isin value="US76029N1063"/>
        </identifiers>
        <balance>96267.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>736442.550000</valUSD>
        <pctVal>0.1111403811</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REVOLUTION MEDICINES INC</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>REVOLUTION MEDICINES INC</title>
        <cusip>76155X100</cusip>
        <identifiers>
          <isin value="US76155X1000"/>
        </identifiers>
        <balance>92384.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8984344.000000</valUSD>
        <pctVal>1.3558741489</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REVOLUTION MEDICINES INC WTS 12/26</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>REVOLUTION MEDICINES INC</title>
        <cusip>76155X118</cusip>
        <identifiers>
          <isin value="US76155X1182"/>
        </identifiers>
        <balance>11096.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>19307.040000</valUSD>
        <pctVal>0.0029137260</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REVVITY INC</name>
        <lei>549300IKL1SDPFI7N655</lei>
        <title>REVVITY INC</title>
        <cusip>714046109</cusip>
        <identifiers>
          <isin value="US7140461093"/>
        </identifiers>
        <balance>17506.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1533700.660000</valUSD>
        <pctVal>0.2314587550</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RHYTHM PHARMACEUTICALS INC</name>
        <lei>529900JPNWXQ8DPLA551</lei>
        <title>RHYTHM PHARMACEUTICALS INC</title>
        <cusip>76243J105</cusip>
        <identifiers>
          <isin value="US76243J1051"/>
        </identifiers>
        <balance>14695.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1278024.150000</valUSD>
        <pctVal>0.1928732812</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RING THERAPEUTICS INC PP</name>
        <lei>N/A</lei>
        <title>RING THERAPEUTICS INC PP</title>
        <cusip>TC4CR9CB8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6123622"/>
        </identifiers>
        <balance>13073.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>60135.800000</valUSD>
        <pctVal>0.0090754068</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROCKET PHARMACEUTICALS INC</name>
        <lei>549300R7VV82YUIN4Y93</lei>
        <title>ROCKET PHARMACEUTICALS INC</title>
        <cusip>77313F106</cusip>
        <identifiers>
          <isin value="US77313F1066"/>
        </identifiers>
        <balance>36464.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>130541.120000</valUSD>
        <pctVal>0.0197006404</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROIVANT SCIENCES LTD</name>
        <lei>549300DL466NY5J6U724</lei>
        <title>ROIVANT SCIENCES LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="BMG762791017"/>
        </identifiers>
        <balance>271253.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7513708.100000</valUSD>
        <pctVal>1.1339328252</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROYALTY PHARMA PLC- CL A</name>
        <lei>549300FGFN7VOK8BZR03</lei>
        <title>ROYALTY PHARMA PLC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="GB00BMVP7Y09"/>
        </identifiers>
        <balance>77100.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3698487.000000</valUSD>
        <pctVal>0.5581579371</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SALUDA MEDICAL INC</name>
        <lei>N/A</lei>
        <title>SALUDA MEDICAL INC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="AU0000432114"/>
        </identifiers>
        <balance>234087.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="AUD" exchangeRt="1.449380"/>
        <valUSD>134555.470000</valUSD>
        <pctVal>0.0203064668</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Saluda Medical Inc Lockup Shs CDI PP</name>
        <lei>N/A</lei>
        <title>SALUDA MEDICAL INC PP restricted cdi</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2CX8OG1"/>
        </identifiers>
        <balance>189460.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="AUD" exchangeRt="1.449380"/>
        <valUSD>107188.700000</valUSD>
        <pctVal>0.0161764050</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>AU</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SARTORIUS AG-VORZUG PREF</name>
        <lei>529900EQV2DY4FOAMU38</lei>
        <title>SARTORIUS AG</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="DE0007165631"/>
        </identifiers>
        <balance>2715.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.865164"/>
        <valUSD>679338.410000</valUSD>
        <pctVal>0.1025224979</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SCHOLAR ROCK HOLDING CORP</name>
        <lei>549300Z1FLPGL4OWJ459</lei>
        <title>SCHOLAR ROCK HOLDING CORP</title>
        <cusip>80706P103</cusip>
        <identifiers>
          <isin value="US80706P1030"/>
        </identifiers>
        <balance>83968.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4127866.880000</valUSD>
        <pctVal>0.6229578913</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SCRIBE THERA SER B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>SCRIBE THERA SER B CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3QFGOY2"/>
        </identifiers>
        <balance>45881.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>277639.700000</valUSD>
        <pctVal>0.0419000532</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SEAPORT THERAPEUTICS SER B CVT PFD PP</name>
        <lei>N/A</lei>
        <title>SEAPORT THERAPEUTICS SER B CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6RVVDR3"/>
        </identifiers>
        <balance>113620.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>539695.000000</valUSD>
        <pctVal>0.0814481835</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SENSORION SA</name>
        <lei>969500P0W8XJ9CGZDP97</lei>
        <title>SENSORION SA</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="FR0012596468"/>
        </identifiers>
        <balance>1029513.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.865164"/>
        <valUSD>488840.210000</valUSD>
        <pctVal>0.0737734223</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>FR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SHATTUCK LABS INC</name>
        <lei>N/A</lei>
        <title>SHATTUCK LABS INC</title>
        <cusip>82024L103</cusip>
        <identifiers>
          <isin value="US82024L1035"/>
        </identifiers>
        <balance>85500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>549765.000000</valUSD>
        <pctVal>0.0829678997</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SIONNA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SIONNA THERAPEUTICS INC</title>
        <cusip>829401108</cusip>
        <identifiers>
          <isin value="US8294011080"/>
        </identifiers>
        <balance>35707.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1431493.630000</valUSD>
        <pctVal>0.2160341598</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SOMALOGIC INC WTS 8/26</name>
        <lei>549300D3W3Q8CN30YO25</lei>
        <title>SOMALOGIC INC</title>
        <cusip>83444K113</cusip>
        <identifiers>
          <isin value="US83444K1135"/>
        </identifiers>
        <balance>4962.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SONOVA HOLDING AG-REG</name>
        <lei>5299004A0QNX7FBNHS61</lei>
        <title>SONOVA HOLDING AG</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="CH0012549785"/>
        </identifiers>
        <balance>6462.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="CHF" exchangeRt="0.799600"/>
        <valUSD>1473422.920000</valUSD>
        <pctVal>0.2223619273</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SPAC PCSC Freenome PIPE COMMIT PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>SPAC PCSC FREENOME PIPE COMMIT PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC8BJ37B4"/>
        </identifiers>
        <balance>26090.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>257586.570000</valUSD>
        <pctVal>0.0388737309</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SPYGLASS PHARMA INC</name>
        <lei>N/A</lei>
        <title>SPYGLASS PHARMA INC</title>
        <cusip>85220G109</cusip>
        <identifiers>
          <isin value="US85220G1094"/>
        </identifiers>
        <balance>17450.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>452129.500000</valUSD>
        <pctVal>0.0682332178</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Spyre Therapeutics Inc</name>
        <lei>52990017AIJPRH3HQH40</lei>
        <title>SPYRE THERAPEUTICS INC</title>
        <cusip>00773J202</cusip>
        <identifiers>
          <isin value="US00773J2024"/>
        </identifiers>
        <balance>52747.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2660558.680000</valUSD>
        <pctVal>0.4015187682</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>STOKE THERAPEUTICS INC</name>
        <lei>549300RD25SS2DIJHJ67</lei>
        <title>STOKE THERAPEUTICS INC</title>
        <cusip>86150R107</cusip>
        <identifiers>
          <isin value="US86150R1077"/>
        </identifiers>
        <balance>28000.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>911680.000000</valUSD>
        <pctVal>0.1375863774</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>STRUCTURE THERAPEUTICS INC ADR</name>
        <lei>N/A</lei>
        <title>STRUCTURE THERAPEUTICS INC</title>
        <cusip>86366E106</cusip>
        <identifiers>
          <isin value="US86366E1064"/>
        </identifiers>
        <balance>77611.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3740850.200000</valUSD>
        <pctVal>0.5645511883</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>STRYKER CORP</name>
        <lei>5493002F0SC4JTBU5137</lei>
        <title>STRYKER CORP</title>
        <cusip>863667101</cusip>
        <identifiers>
          <isin value="US8636671013"/>
        </identifiers>
        <balance>70352.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23116963.680000</valUSD>
        <pctVal>3.4887013959</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SUMMIT THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SUMMIT THERAPEUTICS INC</title>
        <cusip>86627T108</cusip>
        <identifiers>
          <isin value="US86627T1088"/>
        </identifiers>
        <balance>362900.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6880584.000000</valUSD>
        <pctVal>1.0383847696</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>T. Rowe Price Government Reserve Fund</name>
        <lei>5493002Y0IYARJVQ5N24</lei>
        <title>T. Rowe Price Government Reserve Fund</title>
        <cusip>76105Y109</cusip>
        <identifiers>
          <isin value="US76105Y1091"/>
        </identifiers>
        <balance>2941208.620000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2941208.620000</valUSD>
        <pctVal>0.4438731124</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TANGO THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>TANGO THERAPEUTICS INC</title>
        <cusip>87583X109</cusip>
        <identifiers>
          <isin value="US87583X1090"/>
        </identifiers>
        <balance>38900.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>813788.000000</valUSD>
        <pctVal>0.1228129858</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TARSUS PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>TARSUS PHARMACEUTICALS INC</title>
        <cusip>87650L103</cusip>
        <identifiers>
          <isin value="US87650L1035"/>
        </identifiers>
        <balance>11077.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>777051.550000</valUSD>
        <pctVal>0.1172688968</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TECTONIC THERAPEUTIC INC</name>
        <lei>N/A</lei>
        <title>TECTONIC THERAPEUTIC INC</title>
        <cusip>878972108</cusip>
        <identifiers>
          <isin value="US8789721086"/>
        </identifiers>
        <balance>7600.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>234916.000000</valUSD>
        <pctVal>0.0354523971</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TENAX THERAPEUTICS INC</name>
        <lei>549300J03O6B1IJ2B606</lei>
        <title>TENAX THERAPEUTICS INC</title>
        <cusip>88032L605</cusip>
        <identifiers>
          <isin value="US88032L6056"/>
        </identifiers>
        <balance>151450.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2421685.500000</valUSD>
        <pctVal>0.3654691724</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TENET HEALTHCARE CORP</name>
        <lei>0W9AIBT6U6ADJ2I8HK17</lei>
        <title>TENET HEALTHCARE CORP</title>
        <cusip>88033G407</cusip>
        <identifiers>
          <isin value="US88033G4073"/>
        </identifiers>
        <balance>36032.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6799598.720000</valUSD>
        <pctVal>1.0261628592</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TERNS PHARMACEUTICALS INC</name>
        <lei>254900S1ZDQMF4MYP709</lei>
        <title>TERNS PHARMACEUTICALS INC</title>
        <cusip>880881107</cusip>
        <identifiers>
          <isin value="US8808811074"/>
        </identifiers>
        <balance>33976.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1791214.720000</valUSD>
        <pctVal>0.2703215431</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TESSERA THERAPEUTICS SER D CVT PFD PP</name>
        <lei>N/A</lei>
        <title>TESSERA THERAPEUTICS SER D CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6AR2E49"/>
        </identifiers>
        <balance>17248.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>89344.640000</valUSD>
        <pctVal>0.0134834650</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>THERMO FISHER SCIENTIFIC INC</name>
        <lei>HCHV7422L5HDJZCRFL38</lei>
        <title>THERMO FISHER SCIENTIFIC INC</title>
        <cusip>883556102</cusip>
        <identifiers>
          <isin value="US8835561023"/>
        </identifiers>
        <balance>54941.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>27005149.730000</valUSD>
        <pctVal>4.0754878047</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>THIRD ARC BIO SER A CVT PFD PP</name>
        <lei>N/A</lei>
        <title>THIRD ARC BIO SER A CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC5WFUTE5"/>
        </identifiers>
        <balance>240042.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>505096.380000</valUSD>
        <pctVal>0.0762267255</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Treeline Bio Common WTS 8/35 PP</name>
        <lei>N/A</lei>
        <title>TREELINE BIO COMMON WTS 8.35 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC8LDBAV2"/>
        </identifiers>
        <balance>2604.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>18975.350000</valUSD>
        <pctVal>0.0028636689</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TREELINE BIO SER A CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>TREELINE BIO SER A CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0U9C2T7"/>
        </identifiers>
        <balance>106061.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>772866.510000</valUSD>
        <pctVal>0.1166373106</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TREELINE BIO SER A-1 CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>TREELINE BIO SER A-1 CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC51XS4U9"/>
        </identifiers>
        <balance>123059.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>896730.930000</valUSD>
        <pctVal>0.1353303354</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Treeline Bio SER A-2 CVT PFD PP</name>
        <lei>N/A</lei>
        <title>TREELINE BIO SER A-2 NV CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9QDVLP7"/>
        </identifiers>
        <balance>17362.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>126516.890000</valUSD>
        <pctVal>0.0190933228</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TYRA BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>TYRA BIOSCIENCES INC</title>
        <cusip>90240B106</cusip>
        <identifiers>
          <isin value="US90240B1061"/>
        </identifiers>
        <balance>18800.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>720040.000000</valUSD>
        <pctVal>0.1086649868</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TESSERA THERAPEUTICS SER C' CVT PFD PP</name>
        <lei>N/A</lei>
        <title>Tessera Therapeutics, Inc. Series C</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7M24T72"/>
        </identifiers>
        <balance>30439.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>157674.020000</valUSD>
        <pctVal>0.0237954076</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UNITED THERAPEUTICS CORP</name>
        <lei>5299005C4HZL4UWROC14</lei>
        <title>UNITED THERAPEUTICS CORP</title>
        <cusip>91307C102</cusip>
        <identifiers>
          <isin value="US91307C1027"/>
        </identifiers>
        <balance>15087.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8946289.260000</valUSD>
        <pctVal>1.3501311098</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UNITEDHEALTH GROUP INC</name>
        <lei>549300GHBMY8T5GXDE41</lei>
        <title>UNITEDHEALTH GROUP INC</title>
        <cusip>91324P102</cusip>
        <identifiers>
          <isin value="US91324P1021"/>
        </identifiers>
        <balance>75926.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>20544816.340000</valUSD>
        <pctVal>3.1005252435</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VAXCYTE INC</name>
        <lei>254900M7NMHTGASX8D95</lei>
        <title>VAXCYTE INC</title>
        <cusip>92243G108</cusip>
        <identifiers>
          <isin value="US92243G1085"/>
        </identifiers>
        <balance>19250.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1118617.500000</valUSD>
        <pctVal>0.1688163934</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VERA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>VERA THERAPEUTICS INC</title>
        <cusip>92337R101</cusip>
        <identifiers>
          <isin value="US92337R1014"/>
        </identifiers>
        <balance>77381.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3113037.630000</valUSD>
        <pctVal>0.4698047233</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VERILY LIFE SCIENCES LLC SER B UNITS PP</name>
        <lei>5493003ZYK1Z7M670M44</lei>
        <title>VERILY LIFE SCIENCES LLC SER B UNITS PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4V69U94"/>
        </identifiers>
        <balance>5220.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>58191.520000</valUSD>
        <pctVal>0.0087819854</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VERTEX PHARMACEUTICALS INC</name>
        <lei>54930015RAQRRZ5ZGJ91</lei>
        <title>VERTEX PHARMACEUTICALS INC</title>
        <cusip>92532F100</cusip>
        <identifiers>
          <isin value="US92532F1003"/>
        </identifiers>
        <balance>36045.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>16095534.300000</valUSD>
        <pctVal>2.4290609163</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VIATRIS INC</name>
        <lei>254900ZZTSW7NL773X71</lei>
        <title>VIATRIS INC</title>
        <cusip>92556V106</cusip>
        <identifiers>
          <isin value="US92556V1061"/>
        </identifiers>
        <balance>58200.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>786282.000000</valUSD>
        <pctVal>0.1186619120</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VIRIDIAN THERAPEUTICS INC</name>
        <lei>549300C775BNYF550E70</lei>
        <title>VIRIDIAN THERAPEUTICS INC</title>
        <cusip>92790C104</cusip>
        <identifiers>
          <isin value="US92790C1045"/>
        </identifiers>
        <balance>20932.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>409429.920000</valUSD>
        <pctVal>0.0617892018</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>WAVE LIFE SCIENCES LTD</name>
        <lei>54930070006GPKFYZ813</lei>
        <title>WAVE LIFE SCIENCES LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="SG9999014716"/>
        </identifiers>
        <balance>128523.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>931791.750000</valUSD>
        <pctVal>0.1406215463</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>SG</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>WEST PHARMACEUTICAL SERVICES</name>
        <lei>5493007NKRGM1RJQ1P16</lei>
        <title>WEST PHARMACEUTICAL SERVICES INC</title>
        <cusip>955306105</cusip>
        <identifiers>
          <isin value="US9553061055"/>
        </identifiers>
        <balance>6000.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1503840.000000</valUSD>
        <pctVal>0.2269523273</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>XENCOR INC</name>
        <lei>549300V5IF65437JKG30</lei>
        <title>XENCOR INC</title>
        <cusip>98401F105</cusip>
        <identifiers>
          <isin value="US98401F1057"/>
        </identifiers>
        <balance>22853.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>275607.180000</valUSD>
        <pctVal>0.0415933151</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ZAI LAB LTD ADR</name>
        <lei>549300P2UYQ9U5LY1T58</lei>
        <title>ZAI LAB LTD</title>
        <cusip>98887Q104</cusip>
        <identifiers>
          <isin value="US98887Q1040"/>
        </identifiers>
        <balance>13777.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>259145.370000</valUSD>
        <pctVal>0.0391089776</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2026-05-05</ncom:dateSigned>
      <ncom:nameOfApplicant>T. ROWE PRICE EQUITY SERIES, INC.</ncom:nameOfApplicant>
      <ncom:signature>/s/ Alan Dupski</ncom:signature>
      <ncom:signerName>Alan Dupski</ncom:signerName>
      <ncom:title>Treasurer &amp; Vice President</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
