<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/nport" xmlns:com="http://www.sec.gov/edgar/common" xmlns:ncom="http://www.sec.gov/edgar/nportcommon" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0000918294</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000002083</seriesId>
        <classId>C000005448</classId>
        <classId>C000005449</classId>
      </seriesClassInfo>


    </filerInfo>
  </headerData>
  <formData>
    <genInfo>
      <regName>T. ROWE PRICE EQUITY SERIES, INC.</regName>
      <regFileNumber>811-07143</regFileNumber>
      <regCik>0000918294</regCik>
      <regLei>549300U8GAQGX2UFFV03</regLei>
      <regStreet1>1307 Point Street</regStreet1>
      <regCity>Baltimore</regCity>
      <regStateConditional regCountry="US" regState="US-MD"/>
      <regZipOrPostalCode>21231</regZipOrPostalCode>
      <regPhone>410-345-2000</regPhone>
      <seriesName>T. Rowe Price Health Sciences Portfolio</seriesName>
      <seriesId>S000002083</seriesId>
      <seriesLei>23LI9YJ7764IBT5W0K91</seriesLei>
      <repPdEnd>2025-12-31</repPdEnd>
      <repPdDate>2025-12-31</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>731030559.170000</totAssets>
      <totLiabs>1250666.220000</totLiabs>
      <netAssets>729779892.950000</netAssets>
      <assetsAttrMiscSec>33806263.760000</assetsAttrMiscSec>
      <assetsInvested>0.000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.000000</amtPayAftOneYrOther>
      <delayDeliv>0.000000</delayDeliv>
      <standByCommit>553925.920000</standByCommit>
      <liquidPref>0.000000</liquidPref>
      <cshNotRptdInCorD>400.530000</cshNotRptdInCorD>
      <curMetrics>
        <curMetric>
          <curCd>USD</curCd>
          <intrstRtRiskdv01 period10Yr="0.000000" period1Yr="0.000000" period30Yr="0.000000" period3Mon="0.000000" period5Yr="0.000000"/>
          <intrstRtRiskdv100 period10Yr="0.000000" period1Yr="0.000000" period30Yr="0.000000" period3Mon="0.000000" period5Yr="0.000000"/>
        </curMetric>
      </curMetrics>
      <creditSprdRiskInvstGrade period10Yr="0.000000" period1Yr="0.000000" period30Yr="0.000000" period3Mon="0.000000" period5Yr="0.000000"/>
      <creditSprdRiskNonInvstGrade period10Yr="0.000000" period1Yr="0.000000" period30Yr="0.000000" period3Mon="0.000000" period5Yr="0.000000"/>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
          <monthlyTotReturn classId="C000005448" rtn1="7.960000" rtn2="9.160000" rtn3="-1.910000"/>
          <monthlyTotReturn classId="C000005449" rtn1="7.950000" rtn2="9.120000" rtn3="-1.930000"/>
        </monthlyTotReturns>
        <othMon1 netRealizedGain="18065349.41" netUnrealizedAppr="33388227.53"/>
        <othMon2 netRealizedGain="10666226.720000" netUnrealizedAppr="52629242.440000"/>
        <othMon3 netRealizedGain="6930531.230000" netUnrealizedAppr="-21257161.250000"/>
      </returnInfo>
      <mon1Flow redemption="9240400.220000" reinvestment="0.000000" sales="3826488.360000"/>
      <mon2Flow redemption="7235554.610000" reinvestment="0.000000" sales="4919462.690000"/>
      <mon3Flow redemption="12749251.720000" reinvestment="26141513.720000" sales="6215191.770000"/>


    </fundInfo>
    <invstOrSecs>
      <invstOrSec>
        <name>EXACT SCIENCES CMO MILESTONE PP</name>
        <lei>549300VM3X1FYD4N9Z14</lei>
        <title>- EXACT SCIENCES CMO MILESTONE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4Y8OHO5"/>
        </identifiers>
        <balance>167423.910000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ABBVIE INC</name>
        <lei>FR5LCKFTG8054YNNRU85</lei>
        <title>ABBVIE INC</title>
        <cusip>00287Y109</cusip>
        <identifiers>
          <isin value="US00287Y1091"/>
        </identifiers>
        <balance>88426.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>20204456.740000</valUSD>
        <pctVal>2.7685685691</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ABIVAX SA-ADR</name>
        <lei>969500D8TMNB184OJU95</lei>
        <title>ABIVAX SA</title>
        <cusip>00370M103</cusip>
        <identifiers>
          <isin value="US00370M1036"/>
        </identifiers>
        <balance>23445.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3161675.480000</valUSD>
        <pctVal>0.4332368582</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>FR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AFFINIVAX AFX3772 MILESTONE EVENT PP</name>
        <lei>N/A</lei>
        <title>AFFINIVAX AFX3772 MILESTONE EVENT PP</title>
        <cusip>TC2HD0ET2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8072881"/>
        </identifiers>
        <balance>331975.800000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AFFINIVAX EXPENSE FUND PP</name>
        <lei>N/A</lei>
        <title>AFFINIVAX EXPENSE FUND PP</title>
        <cusip>TC929D1E2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8072884"/>
        </identifiers>
        <balance>562.150000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>522.290000</valUSD>
        <pctVal>0.0000715682</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AFFINIVAX NEXT GEN PROD MILESTON EVNT PP</name>
        <lei>N/A</lei>
        <title>AFFINIVAX NEXT GEN PROD MILESTON EVNT PP</title>
        <cusip>TC7BEY6E7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8072883"/>
        </identifiers>
        <balance>331975.800000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AGIOS PHARMACEUTICALS INC</name>
        <lei>529900ONJHY8EOGYT555</lei>
        <title>AGIOS PHARMACEUTICALS INC</title>
        <cusip>00847X104</cusip>
        <identifiers>
          <isin value="US00847X1046"/>
        </identifiers>
        <balance>20957.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>570449.540000</valUSD>
        <pctVal>0.0781673413</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Aktis Oncology SER B CVTPFD PP</name>
        <lei>N/A</lei>
        <title>AKTIS ONCOLOGY SER B CVTPFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0930F05"/>
        </identifiers>
        <balance>134478.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>537912.000000</valUSD>
        <pctVal>0.0737087998</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALIGNMENT HEALTHCARE INC</name>
        <lei>N/A</lei>
        <title>ALIGNMENT HEALTHCARE INC</title>
        <cusip>01625V104</cusip>
        <identifiers>
          <isin value="US01625V1044"/>
        </identifiers>
        <balance>89396.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1765571.000000</valUSD>
        <pctVal>0.2419319876</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALKERMES PLC</name>
        <lei>N/A</lei>
        <title>ALKERMES PLC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="IE00B56GVS15"/>
        </identifiers>
        <balance>16995.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>475520.100000</valUSD>
        <pctVal>0.0651593864</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALLOGENE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ALLOGENE THERAPEUTICS INC</title>
        <cusip>019770106</cusip>
        <identifiers>
          <isin value="US0197701065"/>
        </identifiers>
        <balance>160368.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>219704.160000</valUSD>
        <pctVal>0.0301055376</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALNYLAM PHARMACEUTICALS INC</name>
        <lei>529900S3ZI14OWRJII50</lei>
        <title>ALNYLAM PHARMACEUTICALS INC</title>
        <cusip>02043Q107</cusip>
        <identifiers>
          <isin value="US02043Q1076"/>
        </identifiers>
        <balance>41896.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>16659944.400000</valUSD>
        <pctVal>2.2828724881</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ANNEXON INC</name>
        <lei>N/A</lei>
        <title>ANNEXON INC</title>
        <cusip>03589W102</cusip>
        <identifiers>
          <isin value="US03589W1027"/>
        </identifiers>
        <balance>20477.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>102794.540000</valUSD>
        <pctVal>0.0140856909</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>APOGEE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>APOGEE THERAPEUTICS INC</title>
        <cusip>03770N101</cusip>
        <identifiers>
          <isin value="US03770N1019"/>
        </identifiers>
        <balance>39362.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2971043.760000</valUSD>
        <pctVal>0.4071150478</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARBOR BIO SERIES B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>ARBOR BIO SERIES B CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC89FRFR6"/>
        </identifiers>
        <balance>23994.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>127648.080000</valUSD>
        <pctVal>0.0174913123</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARBOR BIO SERIES C CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>ARBOR BIO SERIES C CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9POPC96"/>
        </identifiers>
        <balance>15714.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>83598.480000</valUSD>
        <pctVal>0.0114553005</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARCELLX INC</name>
        <lei>N/A</lei>
        <title>ARCELLX INC</title>
        <cusip>03940C100</cusip>
        <identifiers>
          <isin value="US03940C1009"/>
        </identifiers>
        <balance>24130.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1573276.000000</valUSD>
        <pctVal>0.2155822619</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARCUTIS BIOTHERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ARCUTIS BIOTHERAPEUTICS INC</title>
        <cusip>03969K108</cusip>
        <identifiers>
          <isin value="US03969K1088"/>
        </identifiers>
        <balance>35300.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1025112.000000</valUSD>
        <pctVal>0.1404686550</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARGENX SE - ADR</name>
        <lei>7245009C5FZE6G9ODQ71</lei>
        <title>ARGENX SE</title>
        <cusip>04016X101</cusip>
        <identifiers>
          <isin value="US04016X1019"/>
        </identifiers>
        <balance>33783.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>28409813.850000</valUSD>
        <pctVal>3.8929291043</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARROWHEAD PHARMACEUTICALS INC</name>
        <lei>549300O3CSB8T7OZ3D66</lei>
        <title>ARROWHEAD PHARMACEUTICALS INC</title>
        <cusip>04280A100</cusip>
        <identifiers>
          <isin value="US04280A1007"/>
        </identifiers>
        <balance>20500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1360995.000000</valUSD>
        <pctVal>0.1864939022</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARSENAL BIOSCIENCES SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>ARSENAL BIOSCIENCES SER C CVT PFD PP</title>
        <cusip>TC5YX3EI8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9828670"/>
        </identifiers>
        <balance>35023.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>650727.340000</valUSD>
        <pctVal>0.0891676170</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ASCENDIS PHARMA A/S - ADR</name>
        <lei>549300B66JN3W3J8GH73</lei>
        <title>ASCENDIS PHARMA A/S</title>
        <cusip>04351P101</cusip>
        <identifiers>
          <isin value="US04351P1012"/>
        </identifiers>
        <balance>43137.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9198533.880000</valUSD>
        <pctVal>1.2604531817</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DK</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ASTRAZENECA PLC-SPONS ADR</name>
        <lei>PY6ZZQWO2IZFZC3IOL08</lei>
        <title>ASTRAZENECA PLC</title>
        <cusip>046353108</cusip>
        <identifiers>
          <isin value="US0463531089"/>
        </identifiers>
        <balance>222678.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>20470788.540000</valUSD>
        <pctVal>2.8050633811</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Atai Beckley NV</name>
        <lei>391200Z8UWPJSNBNCA11</lei>
        <title>ATAI BECKLEY NV</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="NL0015000DX5"/>
        </identifiers>
        <balance>23000.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>94070.000000</valUSD>
        <pctVal>0.0128901880</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AURA BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>AURA BIOSCIENCES INC</title>
        <cusip>05153U107</cusip>
        <identifiers>
          <isin value="US05153U1079"/>
        </identifiers>
        <balance>20070.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>109381.500000</valUSD>
        <pctVal>0.0149882863</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AVALYN PHARMA SER C-1 CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>AVALYN PHARMA SER C-1 CVT PFD STOCK PP</title>
        <cusip>TC6KYIDL7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9013945"/>
        </identifiers>
        <balance>388595.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>309438.200000</valUSD>
        <pctVal>0.0424015793</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AVALYN PHARMA SER D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>AVALYN PHARMA SER D CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC8YZ63P2"/>
        </identifiers>
        <balance>90102.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>71748.220000</valUSD>
        <pctVal>0.0098314876</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AXSOME THERAPEUTICS INC</name>
        <lei>549300EXGR0XLRJEIB95</lei>
        <title>AXSOME THERAPEUTICS INC</title>
        <cusip>05464T104</cusip>
        <identifiers>
          <isin value="US05464T1043"/>
        </identifiers>
        <balance>15053.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2749279.920000</valUSD>
        <pctVal>0.3767272772</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BEAM THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>BEAM THERAPEUTICS INC</title>
        <cusip>07373V105</cusip>
        <identifiers>
          <isin value="US07373V1052"/>
        </identifiers>
        <balance>69393.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1923573.960000</valUSD>
        <pctVal>0.2635827567</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BEONE MEDICINES LTD-ADR</name>
        <lei>549300JFUK6FRD5MH739</lei>
        <title>BEONE MEDICINES LTD</title>
        <cusip>07725L102</cusip>
        <identifiers>
          <isin value="US07725L1026"/>
        </identifiers>
        <balance>5080.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1543354.800000</valUSD>
        <pctVal>0.2114822311</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BEONE MEDICINES LTD</name>
        <lei>549300JFUK6FRD5MH739</lei>
        <title>BEONE MEDICINES LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="CH1391448177"/>
        </identifiers>
        <balance>403552.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="HKD" exchangeRt="7.782700"/>
        <valUSD>9288264.070000</valUSD>
        <pctVal>1.2727486958</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BETA BIONICS INC</name>
        <lei>N/A</lei>
        <title>BETA BIONICS INC</title>
        <cusip>08659B102</cusip>
        <identifiers>
          <isin value="US08659B1026"/>
        </identifiers>
        <balance>24243.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>738684.210000</valUSD>
        <pctVal>0.1012201374</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BICARA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>BICARA THERAPEUTICS INC</title>
        <cusip>055477103</cusip>
        <identifiers>
          <isin value="US0554771032"/>
        </identifiers>
        <balance>50199.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>844849.170000</valUSD>
        <pctVal>0.1157676689</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BICYCLE THERAPEUTICS PLC-ADR</name>
        <lei>213800XKUI6R7GKC3E43</lei>
        <title>BICYCLE THERAPEUTICS PLC</title>
        <cusip>088786108</cusip>
        <identifiers>
          <isin value="US0887861088"/>
        </identifiers>
        <balance>62846.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>444949.680000</valUSD>
        <pctVal>0.0609703945</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BILLIONTOONE INC CL A</name>
        <lei>N/A</lei>
        <title>BILLIONTOONE INC</title>
        <cusip>090168105</cusip>
        <identifiers>
          <isin value="US0901681058"/>
        </identifiers>
        <balance>8522.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>697440.480000</valUSD>
        <pctVal>0.0955686073</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BIO-RAD LABORATORIES-A</name>
        <lei>549300ZC1GPV35XYDK53</lei>
        <title>BIO-RAD LABORATORIES INC</title>
        <cusip>090572207</cusip>
        <identifiers>
          <isin value="US0905722072"/>
        </identifiers>
        <balance>2700.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>818073.000000</valUSD>
        <pctVal>0.1120985941</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BIO-TECHNE CORP</name>
        <lei>54930073RLKQ51TILZ35</lei>
        <title>BIO-TECHNE CORP</title>
        <cusip>09073M104</cusip>
        <identifiers>
          <isin value="US09073M1045"/>
        </identifiers>
        <balance>23500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1382035.000000</valUSD>
        <pctVal>0.1893769633</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BIOHAVEN LTD</name>
        <lei>N/A</lei>
        <title>BIOHAVEN LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="VGG1110E1079"/>
        </identifiers>
        <balance>50293.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>567807.970000</valUSD>
        <pctVal>0.0778053733</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>VG</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Blue Marlin Therapeutics Common Stock PP</name>
        <lei>N/A</lei>
        <title>BLUE MARLIN THERAPEUTICS COMMON STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1BZ3EG4"/>
        </identifiers>
        <balance>81.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8.100000</valUSD>
        <pctVal>0.0000011099</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BLUEJAY THERAPEUTICS SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>BLUEJAY THERAPEUTICS SER C CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3VHRH15"/>
        </identifiers>
        <balance>130259.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1596975.340000</valUSD>
        <pctVal>0.2188297260</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BOSTON SCIENTIFIC CORP</name>
        <lei>Y6ZDD9FP4P8JSSJMW954</lei>
        <title>BOSTON SCIENTIFIC CORP</title>
        <cusip>101137107</cusip>
        <identifiers>
          <isin value="US1011371077"/>
        </identifiers>
        <balance>121961.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>11628981.350000</valUSD>
        <pctVal>1.5934916079</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BridgeBio Oncology Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>BRIDGEBIO ONCOLOGY THERAPEUTICS INC</title>
        <cusip>107924102</cusip>
        <identifiers>
          <isin value="US1079241022"/>
        </identifiers>
        <balance>39553.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>495203.560000</valUSD>
        <pctVal>0.0678565640</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BRIDGEBIO PHARMA INC</name>
        <lei>54930028YG89VTY2J114</lei>
        <title>BRIDGEBIO PHARMA INC</title>
        <cusip>10806X102</cusip>
        <identifiers>
          <isin value="US10806X1028"/>
        </identifiers>
        <balance>54569.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4173982.810000</valUSD>
        <pctVal>0.5719509198</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BRIGHTSPRING HEALTH SERVICES</name>
        <lei>N/A</lei>
        <title>BRIGHTSPRING HEALTH SERVICES INC</title>
        <cusip>10950A106</cusip>
        <identifiers>
          <isin value="US10950A1060"/>
        </identifiers>
        <balance>153703.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5756177.350000</valUSD>
        <pctVal>0.7887552679</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cabaletta Bio Common WTS 09/26 PP</name>
        <lei>N/A</lei>
        <title>CABALETTA BIO COMMON WTS 09/26 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC04VICN9"/>
        </identifiers>
        <balance>93835.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CABALETTA BIO INC</name>
        <lei>N/A</lei>
        <title>CABALETTA BIO INC</title>
        <cusip>12674W109</cusip>
        <identifiers>
          <isin value="US12674W1099"/>
        </identifiers>
        <balance>85535.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>187321.650000</valUSD>
        <pctVal>0.0256682394</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CAPSULE CORP SERIES 1-D CVT PFD STOCK</name>
        <lei>N/A</lei>
        <title>CAPSULE CORP SERIES 1-D CVT PFD STOCK</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6MJWXO1"/>
        </identifiers>
        <balance>38140.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>69414.800000</valUSD>
        <pctVal>0.0095117447</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CAPSULE CORP SERIES E CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>CAPSULE CORP SERIES E CVT PFD STOCK PP</title>
        <cusip>TC0YJ3TD4</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8626377"/>
        </identifiers>
        <balance>40875.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>74392.500000</valUSD>
        <pctVal>0.0101938270</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CARDINAL HEALTH INC</name>
        <lei>CCU46N3GJMF4OK4N7U60</lei>
        <title>CARDINAL HEALTH INC</title>
        <cusip>14149Y108</cusip>
        <identifiers>
          <isin value="US14149Y1082"/>
        </identifiers>
        <balance>19671.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4042390.500000</valUSD>
        <pctVal>0.5539191391</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CARIS LIFE SCIENCES INC</name>
        <lei>549300LX5LO78M5VPY43</lei>
        <title>CARIS LIFE SCIENCES INC</title>
        <cusip>142152107</cusip>
        <identifiers>
          <isin value="US1421521071"/>
        </identifiers>
        <balance>109250.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2947565.000000</valUSD>
        <pctVal>0.4038978093</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CELCUITY INC</name>
        <lei>25490070W7UU7W2SEY87</lei>
        <title>CELCUITY INC</title>
        <cusip>15102K100</cusip>
        <identifiers>
          <isin value="US15102K1007"/>
        </identifiers>
        <balance>35581.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3548848.940000</valUSD>
        <pctVal>0.4862903150</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CELLANOME SERIES A CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>CELLANOME SERIES A CVT PFD STOCK PP</title>
        <cusip>TC13MXKE8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7298443"/>
        </identifiers>
        <balance>89839.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>781599.300000</valUSD>
        <pctVal>0.1071006899</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CELLDEX THERAPEUTICS INC</name>
        <lei>529900F018DMYWH38923</lei>
        <title>CELLDEX THERAPEUTICS INC</title>
        <cusip>15117B202</cusip>
        <identifiers>
          <isin value="US15117B2025"/>
        </identifiers>
        <balance>23813.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>646761.080000</valUSD>
        <pctVal>0.0886241299</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CENCORA INC</name>
        <lei>AI8GXW8LG5WK7E9UD086</lei>
        <title>CENCORA INC</title>
        <cusip>03073E105</cusip>
        <identifiers>
          <isin value="US03073E1055"/>
        </identifiers>
        <balance>12939.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4370147.250000</valUSD>
        <pctVal>0.5988308656</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CENTENE CORP</name>
        <lei>549300Z7JJ4TQSQGT333</lei>
        <title>CENTENE CORP</title>
        <cusip>15135B101</cusip>
        <identifiers>
          <isin value="US15135B1017"/>
        </identifiers>
        <balance>34600.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1423790.000000</valUSD>
        <pctVal>0.1950985515</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CENTESSA PHARMACEUTICALS-ADR</name>
        <lei>213800GIDAARDSKOI827</lei>
        <title>CENTESSA PHARMACEUTICALS PLC</title>
        <cusip>152309100</cusip>
        <identifiers>
          <isin value="US1523091007"/>
        </identifiers>
        <balance>135268.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3383052.680000</valUSD>
        <pctVal>0.4635716485</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CG ONCOLOGY INC</name>
        <lei>N/A</lei>
        <title>CG ONCOLOGY INC</title>
        <cusip>156944100</cusip>
        <identifiers>
          <isin value="US1569441009"/>
        </identifiers>
        <balance>63647.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2642623.440000</valUSD>
        <pctVal>0.3621123938</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NCHROMA BIO SER I CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>CHROMA MEDICINE SER I CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3N6OVC2"/>
        </identifiers>
        <balance>354997.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>354997.000000</valUSD>
        <pctVal>0.0486443931</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CHROMACODE INC PP</name>
        <lei>N/A</lei>
        <title>CHROMACODE INC PP</title>
        <cusip>TC43UPY99</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7573456"/>
        </identifiers>
        <balance>28.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>135.510000</valUSD>
        <pctVal>0.0000185686</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Chromacode INC SER AA CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>CHROMACODE INC SER AA CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7G6YEM8"/>
        </identifiers>
        <balance>2002.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9689.280000</valUSD>
        <pctVal>0.0013276990</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CHUGAI PHARMACEUTICAL CO LTD</name>
        <lei>529900T9LAII161DCN95</lei>
        <title>CHUGAI PHARMACEUTICAL CO LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="JP3519400000"/>
        </identifiers>
        <balance>65300.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="JPY" exchangeRt="156.640000"/>
        <valUSD>3425740.480000</valUSD>
        <pctVal>0.4694210560</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>JP</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CIGNA GROUP/THE</name>
        <lei>549300VIWYMSIGT1U456</lei>
        <title>CIGNA GROUP/THE</title>
        <cusip>125523100</cusip>
        <identifiers>
          <isin value="US1255231003"/>
        </identifiers>
        <balance>20881.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5747077.630000</valUSD>
        <pctVal>0.7875083550</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CLEAR LABS SER D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>CLEAR LABS SER D CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC5HJP6Y6"/>
        </identifiers>
        <balance>18600.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>57966.900000</valUSD>
        <pctVal>0.0079430662</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CLEAR LABS SERIES C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>CLEAR LABS SERIES C CVT PFD PP</title>
        <cusip>TC385IBS6</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6302485"/>
        </identifiers>
        <balance>171440.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>542401.870000</valUSD>
        <pctVal>0.0743240360</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CLEERLY SER C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>CLEERLY SER C CVT PFD STK PP</title>
        <cusip>TC1A1CZJ4</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7878855"/>
        </identifiers>
        <balance>26533.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>465654.150000</valUSD>
        <pctVal>0.0638074787</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Climb Bio Inc</name>
        <lei>N/A</lei>
        <title>CLIMB BIO INC</title>
        <cusip>28658R106</cusip>
        <identifiers>
          <isin value="US28658R1068"/>
        </identifiers>
        <balance>90300.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>361200.000000</valUSD>
        <pctVal>0.0494943754</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>COGENT BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>COGENT BIOSCIENCES INC</title>
        <cusip>19240Q201</cusip>
        <identifiers>
          <isin value="US19240Q2012"/>
        </identifiers>
        <balance>20611.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>732102.720000</valUSD>
        <pctVal>0.1003182915</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>COLOR HEALTH SR D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>COLOR HEALTH SER D CVT PFD STOCK PP</title>
        <cusip>TC1HL9RU8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5762425"/>
        </identifiers>
        <balance>13310.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>255418.900000</valUSD>
        <pctVal>0.0349994433</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>COLOR HEALTH SR D-1 CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>COLOR HEALTH SERIES D-1 CVT PFD STOCK PP</title>
        <cusip>TC3KSMZE0</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5763427"/>
        </identifiers>
        <balance>20165.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>271824.200000</valUSD>
        <pctVal>0.0372474225</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>COLOR HEALTH SERIES E CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>COLOR HEALTH SERIES E CVT PFD STOCK PP</title>
        <cusip>TC4SC4HB5</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6978860"/>
        </identifiers>
        <balance>1991.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>81631.000000</valUSD>
        <pctVal>0.0111857014</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CRESCENT BIOPHARMA INC</name>
        <lei>549300TZ84FFU2J2J459</lei>
        <title>CRESCENT BIOPHARMA INC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="KYG2545C1042"/>
        </identifiers>
        <balance>17631.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>209103.660000</valUSD>
        <pctVal>0.0286529763</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CRINETICS PHARMACEUTICALS IN</name>
        <lei>549300Q1CNFXK5P31D28</lei>
        <title>CRINETICS PHARMACEUTICALS INC</title>
        <cusip>22663K107</cusip>
        <identifiers>
          <isin value="US22663K1079"/>
        </identifiers>
        <balance>70994.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3304770.700000</valUSD>
        <pctVal>0.4528448553</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CVS HEALTH CORP</name>
        <lei>549300EJG376EN5NQE29</lei>
        <title>CVS HEALTH CORP</title>
        <cusip>126650100</cusip>
        <identifiers>
          <isin value="US1266501006"/>
        </identifiers>
        <balance>79090.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6276582.400000</valUSD>
        <pctVal>0.8600651321</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CYTOKINETICS INC</name>
        <lei>549300BE5DY1HW7IHA64</lei>
        <title>CYTOKINETICS INC</title>
        <cusip>23282W605</cusip>
        <identifiers>
          <isin value="US23282W6057"/>
        </identifiers>
        <balance>52606.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3342585.240000</valUSD>
        <pctVal>0.4580264916</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DANAHER CORP</name>
        <lei>S4BKK9OTCEWQ3YHPFM11</lei>
        <title>DANAHER CORP</title>
        <cusip>235851102</cusip>
        <identifiers>
          <isin value="US2358511028"/>
        </identifiers>
        <balance>86125.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>19715735.000000</valUSD>
        <pctVal>2.7016001935</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Delfi Diagnostics CVT Prom Note PP</name>
        <lei>N/A</lei>
        <title>DELFI DIAGNOSTICS CVT PROM NOTE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC787QA79"/>
        </identifiers>
        <balance>78284.580000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>78284.580000</valUSD>
        <pctVal>0.0107271495</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2027-01-29</maturityDt>
          <couponKind>None</couponKind>
          <annualizedRt>0.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>DELFI DIAGNOSTICS INC PP</name>
              <title>DELFI DIAGNOSTICS INC PP</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DELFI DIAGNOSTICS SR A CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>DELFI DIAGNOSTICS SR A CVT PFD STOCK PP</title>
        <cusip>TC0LOSSE0</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5840456"/>
        </identifiers>
        <balance>154525.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>604192.750000</valUSD>
        <pctVal>0.0827910930</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DELFI DIAGNOSTICS SR B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>DELFI DIAGNOSTICS SR B CVT PFD STOCK PP</title>
        <cusip>TC7ZV25B2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7864785"/>
        </identifiers>
        <balance>84104.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>328846.640000</valUSD>
        <pctVal>0.0450610716</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DENALI THERAPEUTICS INC</name>
        <lei>549300ZTQ2HO18L3Q830</lei>
        <title>DENALI THERAPEUTICS INC</title>
        <cusip>24823R105</cusip>
        <identifiers>
          <isin value="US24823R1059"/>
        </identifiers>
        <balance>62136.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1025865.360000</valUSD>
        <pctVal>0.1405718861</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DIANTHUS THERAPEUTICS INC</name>
        <lei>549300Z3N6ODPCOFC890</lei>
        <title>DIANTHUS THERAPEUTICS INC</title>
        <cusip>252828108</cusip>
        <identifiers>
          <isin value="US2528281080"/>
        </identifiers>
        <balance>11616.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>478695.360000</valUSD>
        <pctVal>0.0655944847</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DISC MEDICINE INC</name>
        <lei>N/A</lei>
        <title>DISC MEDICINE INC</title>
        <cusip>254604101</cusip>
        <identifiers>
          <isin value="US2546041011"/>
        </identifiers>
        <balance>25617.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2034245.970000</valUSD>
        <pctVal>0.2787478786</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DNA SCRIPT SERIES C CVT PFD STOCK PP</name>
        <lei>8945001SCRZOZAUEFH64</lei>
        <title>DNA SCRIPT SERIES C CVT PFD STOCK PP</title>
        <cusip>TC3XW4UW2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7232456"/>
        </identifiers>
        <balance>1132.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.850919"/>
        <valUSD>157989.560000</valUSD>
        <pctVal>0.0216489330</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>FR</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EDWARDS LIFESCIENCES CORP</name>
        <lei>YA13X31F3V31L8TMPR58</lei>
        <title>EDWARDS LIFESCIENCES CORP</title>
        <cusip>28176E108</cusip>
        <identifiers>
          <isin value="US28176E1082"/>
        </identifiers>
        <balance>33081.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2820155.250000</valUSD>
        <pctVal>0.3864391548</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EIKON THERA SERIES B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>EIKON THERA SERIES B CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9PUZ8Z4"/>
        </identifiers>
        <balance>34286.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>200382.740000</valUSD>
        <pctVal>0.0274579694</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Eikon Therapeutic SER B-1 CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>EIKON THERA SERIES B-1 CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC08RE2M7"/>
        </identifiers>
        <balance>34790.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>203328.350000</valUSD>
        <pctVal>0.0278615994</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EIKON THERAPEUTICS SER C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>EIKON THERAPEUTICS SER C CVT PFD STK PP</title>
        <cusip>TC0ZK0Q06</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8876187"/>
        </identifiers>
        <balance>7198.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>42068.340000</valUSD>
        <pctVal>0.0057645244</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Eikon Therapeutic SER C-1 CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>EIKON THERAPEUTICS SER C-1 CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3CXBIE5"/>
        </identifiers>
        <balance>6893.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>40285.780000</valUSD>
        <pctVal>0.0055202645</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EIKON THERAPEUTIC SER D CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>EIKON THERAPEUTICS SER D CVT PFD STK PP</title>
        <cusip>TC8MOJAD1</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="10292872"/>
        </identifiers>
        <balance>41686.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>243631.660000</valUSD>
        <pctVal>0.0333842659</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELANCO ANIMAL HEALTH INC</name>
        <lei>549300SHPNDCE059M934</lei>
        <title>ELANCO ANIMAL HEALTH INC</title>
        <cusip>28414H103</cusip>
        <identifiers>
          <isin value="US28414H1032"/>
        </identifiers>
        <balance>24400.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>552172.000000</valUSD>
        <pctVal>0.0756628136</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELEMENT BIOSCIENCES SER C CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES SER C CVT PFD STOCK</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9YLUNV8"/>
        </identifiers>
        <balance>38785.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>266065.100000</valUSD>
        <pctVal>0.0364582667</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELEMENT BIOSCIENCES SER D CVT PFD PP</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES SER D CVT PFD PP</title>
        <cusip>TC3OATBR3</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9824045"/>
        </identifiers>
        <balance>13556.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>75235.800000</valUSD>
        <pctVal>0.0103093824</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELEMENT BIOSCIENCES SER D-1 CVT PFD PP</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES SER D-1 CVT PFD PP</title>
        <cusip>TC141T8S1</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9824046"/>
        </identifiers>
        <balance>13556.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>75235.800000</valUSD>
        <pctVal>0.0103093824</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELEVANCE HEALTH INC</name>
        <lei>8MYN82XMYQH89CTMTH67</lei>
        <title>ELEVANCE HEALTH INC</title>
        <cusip>036752103</cusip>
        <identifiers>
          <isin value="US0367521038"/>
        </identifiers>
        <balance>18234.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6391928.700000</valUSD>
        <pctVal>0.8758707607</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELI LILLY &amp; CO</name>
        <lei>FRDRIPF3EKNDJ2CQJL29</lei>
        <title>ELI LILLY &amp; CO</title>
        <cusip>532457108</cusip>
        <identifiers>
          <isin value="US5324571083"/>
        </identifiers>
        <balance>84510.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>90821206.800000</valUSD>
        <pctVal>12.4450135825</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENCOMPASS HEALTH CORP</name>
        <lei>549300FVRPM9DRQZRG64</lei>
        <title>ENCOMPASS HEALTH CORP</title>
        <cusip>29261A100</cusip>
        <identifiers>
          <isin value="US29261A1007"/>
        </identifiers>
        <balance>9403.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>998034.420000</valUSD>
        <pctVal>0.1367582787</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENDEAVOR BIO SERIES B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>END EAVOR BIO SERIES B CVT PFD STOCK PP</title>
        <cusip>TC0KH48I6</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7395452"/>
        </identifiers>
        <balance>84304.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>550049.880000</valUSD>
        <pctVal>0.0753720245</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENDEAVOR BIO SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>ENDEAVOR BIO SER C CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1MA9814"/>
        </identifiers>
        <balance>23627.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>154156.720000</valUSD>
        <pctVal>0.0211237281</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENTRADA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ENTRADA THERAPEUTICS INC</title>
        <cusip>29384C108</cusip>
        <identifiers>
          <isin value="US29384C1080"/>
        </identifiers>
        <balance>19854.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>204099.120000</valUSD>
        <pctVal>0.0279672161</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EVOMMUNE INC</name>
        <lei>N/A</lei>
        <title>EVOMMUNE INC</title>
        <cusip>30054Y107</cusip>
        <identifiers>
          <isin value="US30054Y1073"/>
        </identifiers>
        <balance>16349.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>279894.880000</valUSD>
        <pctVal>0.0383533285</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EXACT SCIENCES FDA MILESTONE PP</name>
        <lei>549300VM3X1FYD4N9Z14</lei>
        <title>EXACT SCIENCES FDA MILESTONE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC81LO8E0"/>
        </identifiers>
        <balance>83711.960000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MED INC SER D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>FOG PHARMA SER D CVT PFD STOCK PP</title>
        <cusip>TC2VY7UZ1</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8505067"/>
        </identifiers>
        <balance>27546.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>201598.160000</valUSD>
        <pctVal>0.0276245155</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MED INC SER E CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>FOG PHARMA SER E CVT PFD PP</title>
        <cusip>TC0O5RRO6</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9692804"/>
        </identifiers>
        <balance>29808.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>185039.120000</valUSD>
        <pctVal>0.0253554698</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MED INC SER C CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>FOG PHARMACEUTICALS SERIES C CVT PFD STOCK PP</title>
        <cusip>TC4W1BVL4</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5837441"/>
        </identifiers>
        <balance>19483.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>164832.020000</valUSD>
        <pctVal>0.0225865390</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME HOLDINGS SER B CVT PFD PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>FREENOME HOLDINGS SER B CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3E3G6L0"/>
        </identifiers>
        <balance>71397.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>247581.510000</valUSD>
        <pctVal>0.0339255044</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME HOLDINGS SER C CVT PFD PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>FREENOME HOLDINGS SER C CVT PFD PP</title>
        <cusip>TC87S2BF1</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5259505"/>
        </identifiers>
        <balance>41732.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>144712.970000</valUSD>
        <pctVal>0.0198296735</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME HOLDINGS SER D CVT PFD PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>FREENOME HOLDINGS SER D CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC55AWPR0"/>
        </identifiers>
        <balance>23669.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>82076.370000</valUSD>
        <pctVal>0.0112467294</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME HOLDINGS SER F CVT PFD PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>FREENOME HOLDINGS SER F CVT PFD PP</title>
        <cusip>TC17ZDYA2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="9677139"/>
        </identifiers>
        <balance>8542.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>29620.870000</valUSD>
        <pctVal>0.0040588772</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Galvanize Therapeutics Ser C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>GALVANIZE THERAPEUTICS SER C CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3P6JXA0"/>
        </identifiers>
        <balance>445669.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>236119.890000</valUSD>
        <pctVal>0.0323549460</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENEDX HOLDINGS CORP</name>
        <lei>N/A</lei>
        <title>GENEDX HOLDINGS CORP</title>
        <cusip>81663L200</cusip>
        <identifiers>
          <isin value="US81663L2007"/>
        </identifiers>
        <balance>8772.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1140886.320000</valUSD>
        <pctVal>0.1563329342</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENEDX HOLDINGS CORP WTS 7/26</name>
        <lei>N/A</lei>
        <title>GENEDX HOLDINGS CORP</title>
        <cusip>81663L119</cusip>
        <identifiers>
          <isin value="US81663L1199"/>
        </identifiers>
        <balance>11396.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>540.170000</valUSD>
        <pctVal>0.0000740182</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENERATE BIO SER B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>GENERATE BIO SER B CVT PFD STOCK PP</title>
        <cusip>TC5CQ34B0</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6758509"/>
        </identifiers>
        <balance>84485.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1001147.250000</valUSD>
        <pctVal>0.1371848224</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENERATE BIOMEDICINES INC SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>GENERATE BIOMEDICINES INC SER C CVT PFD</title>
        <cusip>TC3JNBFQ7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8867504"/>
        </identifiers>
        <balance>17003.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>201485.550000</valUSD>
        <pctVal>0.0276090849</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENERATION BIO CO</name>
        <lei>N/A</lei>
        <title>GENERATION BIO CO</title>
        <cusip>37148K209</cusip>
        <identifiers>
          <isin value="US37148K2096"/>
        </identifiers>
        <balance>9145.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>51943.600000</valUSD>
        <pctVal>0.0071177078</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENESIS THERA SER A CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>GENESIS THERA SER A CVT PFD STOCK PP</title>
        <cusip>TC08XH789</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5657422"/>
        </identifiers>
        <balance>37471.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>191386.880000</valUSD>
        <pctVal>0.0262252882</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GENESIS THERA SER B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>GENESIS THERA SEV B CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2CU1CQ0"/>
        </identifiers>
        <balance>91103.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>465317.680000</valUSD>
        <pctVal>0.0637613731</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GILEAD SCIENCES INC</name>
        <lei>549300WTZWR07K8MNV44</lei>
        <title>GILEAD SCIENCES INC</title>
        <cusip>375558103</cusip>
        <identifiers>
          <isin value="US3755581036"/>
        </identifiers>
        <balance>129684.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>15917414.160000</valUSD>
        <pctVal>2.1811253384</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GINKGO BIOWORKS HOLDINGS INC</name>
        <lei>N/A</lei>
        <title>GINKGO BIOWORKS HOLDINGS INC</title>
        <cusip>37611X209</cusip>
        <identifiers>
          <isin value="US37611X2099"/>
        </identifiers>
        <balance>2281.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>18955.110000</valUSD>
        <pctVal>0.0025973736</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GUARDANT HEALTH INC</name>
        <lei>254900M8C3E5VC8BR186</lei>
        <title>GUARDANT HEALTH INC</title>
        <cusip>40131M109</cusip>
        <identifiers>
          <isin value="US40131M1099"/>
        </identifiers>
        <balance>65832.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6724080.480000</valUSD>
        <pctVal>0.9213847278</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GYROSCOPE THERAPEUTICS MLSTNE PYMT 1 PP</name>
        <lei>21380066POJ2YSHZAD73</lei>
        <title>GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 1 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7SL0DD0"/>
        </identifiers>
        <balance>253263.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GYROSCOPE THERAPEUTICS MLSTNE PYMT 2 PP</name>
        <lei>21380066POJ2YSHZAD73</lei>
        <title>GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 2 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2NYGIQ3"/>
        </identifiers>
        <balance>168785.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GYROSCOPE THERAPEUTICS MLSTNE PYMT 3 PP</name>
        <lei>21380066POJ2YSHZAD73</lei>
        <title>GYROSCOPE THERAPEUTICS MILESTONE PAYMENT 3 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6SL2UQ9"/>
        </identifiers>
        <balance>168785.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GALVANIZE THERA SER C-1 CVT PFD PP</name>
        <lei>N/A</lei>
        <title>Galvanize Therapeutics Series C-1 CVT PFD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6AKD500"/>
        </identifiers>
        <balance>1656003.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>877366.950000</valUSD>
        <pctVal>0.1202235028</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GINKGO BIOWORKS HLDS ERN OUT SHS 600 PP</name>
        <lei>N/A</lei>
        <title>Ginkgo Bioworks Holdings Earn Out Shares $15.00 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0XCAKJ3"/>
        </identifiers>
        <balance>242.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GINKGO BIOWORKS HLDS ERN OUT SHS 700 PP</name>
        <lei>N/A</lei>
        <title>Ginkgo Bioworks Holdings Earn Out Shares $17.50 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1WVCL58"/>
        </identifiers>
        <balance>242.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GINKGO BIOWORKS HLDS ERN OUT SH 800 PP</name>
        <lei>N/A</lei>
        <title>Ginkgo Bioworks Holdings Earn Out Shares $20.00 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC67CJNT0"/>
        </identifiers>
        <balance>242.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HCA HEALTHCARE INC</name>
        <lei>529900PH4ZGUH2MNEU89</lei>
        <title>HCA HEALTHCARE INC</title>
        <cusip>40412C101</cusip>
        <identifiers>
          <isin value="US40412C1018"/>
        </identifiers>
        <balance>14225.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6641083.500000</valUSD>
        <pctVal>0.9100118493</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HEARTFLOW INC</name>
        <lei>N/A</lei>
        <title>HEARTFLOW INC</title>
        <cusip>42238D107</cusip>
        <identifiers>
          <isin value="US42238D1072"/>
        </identifiers>
        <balance>20745.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>604716.750000</valUSD>
        <pctVal>0.0828628955</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HIMS &amp; HERS HEALTH INC</name>
        <lei>254900V041EIVTSB6D58</lei>
        <title>HIMS &amp; HERS HEALTH INC</title>
        <cusip>433000106</cusip>
        <identifiers>
          <isin value="US4330001060"/>
        </identifiers>
        <balance>6500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>211055.000000</valUSD>
        <pctVal>0.0289203638</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HONOR TECHNOLOGY SER D CVT PFD PP</name>
        <lei>N/A</lei>
        <title>HONOR TECHNOLOGY SER D CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9LOECG4"/>
        </identifiers>
        <balance>140829.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>188710.860000</valUSD>
        <pctVal>0.0258585995</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HONOR TECHNOLOGY SER E CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>HONOR TECHNOLOGY SER E CVT PFD STOCK PP</title>
        <cusip>TC2V4FT13</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6871504"/>
        </identifiers>
        <balance>94916.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>127187.440000</valUSD>
        <pctVal>0.0174281919</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IDEAYA BIOSCIENCES INC</name>
        <lei>549300ULW08F62IJML11</lei>
        <title>IDEAYA BIOSCIENCES INC</title>
        <cusip>45166A102</cusip>
        <identifiers>
          <isin value="US45166A1025"/>
        </identifiers>
        <balance>16771.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>579773.470000</valUSD>
        <pctVal>0.0794449773</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IDEXX LABORATORIES INC</name>
        <lei>OGMTXK0LUU1HKV2P0J84</lei>
        <title>IDEXX LABORATORIES INC</title>
        <cusip>45168D104</cusip>
        <identifiers>
          <isin value="US45168D1046"/>
        </identifiers>
        <balance>8132.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5501541.960000</valUSD>
        <pctVal>0.7538631871</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMATICS NV</name>
        <lei>984500DC691EZ96AF394</lei>
        <title>IMMATICS NV</title>
        <cusip>N44445109</cusip>
        <identifiers>
          <isin value="NL0015285941"/>
        </identifiers>
        <balance>38500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>404250.000000</valUSD>
        <pctVal>0.0553934144</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNEERING CORP - CLASS A</name>
        <lei>N/A</lei>
        <title>IMMUNEERING CORP</title>
        <cusip>45254E107</cusip>
        <identifiers>
          <isin value="US45254E1073"/>
        </identifiers>
        <balance>51854.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>341199.320000</valUSD>
        <pctVal>0.0467537299</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOCORE HOLDINGS CB 2.50% 2/30</name>
        <lei>213800IUE3DFS84BVN18</lei>
        <title>IMMUNOCORE HOLDINGS PLC</title>
        <cusip>45258DAB1</cusip>
        <identifiers>
          <isin value="US45258DAB10"/>
        </identifiers>
        <balance>739000.000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>668662.240000</valUSD>
        <pctVal>0.0916251936</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2030-02-01</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>2.5000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>IMMUNOCORE HOLDINGS PLC-ADR</name>
              <title>IMMUNOCORE HOLDINGS PLC-ADR</title>
              <curCd>USD</curCd>
              <identifiers>
                <isin value="US45258D1054"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="10.560100" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOCORE HOLDINGS PLC-ADR</name>
        <lei>213800IUE3DFS84BVN18</lei>
        <title>IMMUNOCORE HOLDINGS PLC</title>
        <cusip>45258D105</cusip>
        <identifiers>
          <isin value="US45258D1054"/>
        </identifiers>
        <balance>47304.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1641921.840000</valUSD>
        <pctVal>0.2249886378</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOME INC</name>
        <lei>N/A</lei>
        <title>IMMUNOME INC</title>
        <cusip>45257U108</cusip>
        <identifiers>
          <isin value="US45257U1088"/>
        </identifiers>
        <balance>131691.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2828722.680000</valUSD>
        <pctVal>0.3876131293</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOVANT INC</name>
        <lei>N/A</lei>
        <title>IMMUNOVANT INC</title>
        <cusip>45258J102</cusip>
        <identifiers>
          <isin value="US45258J1025"/>
        </identifiers>
        <balance>31595.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>803144.900000</valUSD>
        <pctVal>0.1100530321</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INCYTE CORP</name>
        <lei>549300Z4WN6JVZ3T4680</lei>
        <title>INCYTE CORP</title>
        <cusip>45337C102</cusip>
        <identifiers>
          <isin value="US45337C1027"/>
        </identifiers>
        <balance>34883.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3445393.910000</valUSD>
        <pctVal>0.4721141187</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSITRO SER B CVT PFD PP</name>
        <lei>N/A</lei>
        <title>INSITRO SER B CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC14F72Z4"/>
        </identifiers>
        <balance>39793.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>727857.740000</valUSD>
        <pctVal>0.0997366120</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSITRO SER C CVT PFD PP</name>
        <lei>N/A</lei>
        <title>INSITRO SER C CVT PFD PP</title>
        <cusip>TC3HHHWL7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6095464"/>
        </identifiers>
        <balance>26282.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>480726.690000</valUSD>
        <pctVal>0.0658728330</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSMED INC</name>
        <lei>529900Q55QAG41CCAC11</lei>
        <title>INSMED INC</title>
        <cusip>457669307</cusip>
        <identifiers>
          <isin value="US4576693075"/>
        </identifiers>
        <balance>78312.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>13629420.480000</valUSD>
        <pctVal>1.8676070157</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INSPIRE MEDICAL SYSTEMS INC</name>
        <lei>549300XQQCQ7HCJKTW25</lei>
        <title>INSPIRE MEDICAL SYSTEMS INC</title>
        <cusip>457730109</cusip>
        <identifiers>
          <isin value="US4577301090"/>
        </identifiers>
        <balance>8600.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>793178.000000</valUSD>
        <pctVal>0.1086872916</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INTUITIVE SURGICAL INC</name>
        <lei>54930052SRG011710797</lei>
        <title>INTUITIVE SURGICAL INC</title>
        <cusip>46120E602</cusip>
        <identifiers>
          <isin value="US46120E6023"/>
        </identifiers>
        <balance>57803.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>32737307.080000</valUSD>
        <pctVal>4.4859151912</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IONIS PHARMACEUTICALS INC</name>
        <lei>549300SI4ZGLG0BLUZ92</lei>
        <title>IONIS PHARMACEUTICALS INC</title>
        <cusip>462222100</cusip>
        <identifiers>
          <isin value="US4622221004"/>
        </identifiers>
        <balance>63770.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5044844.700000</valUSD>
        <pctVal>0.6912830497</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IOVANCE BIOTHERAPEUTICS INC</name>
        <lei>2549002L8WT2ACU5Q878</lei>
        <title>IOVANCE BIOTHERAPEUTICS INC</title>
        <cusip>462260100</cusip>
        <identifiers>
          <isin value="US4622601007"/>
        </identifiers>
        <balance>42849.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>116977.770000</valUSD>
        <pctVal>0.0160291851</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IQVIA HOLDINGS INC</name>
        <lei>549300W3R20NM4KQPH86</lei>
        <title>IQVIA HOLDINGS INC</title>
        <cusip>46266C105</cusip>
        <identifiers>
          <isin value="US46266C1053"/>
        </identifiers>
        <balance>10076.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2271231.160000</valUSD>
        <pctVal>0.3112213946</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>JANUX THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>JANUX THERAPEUTICS INC</title>
        <cusip>47103J105</cusip>
        <identifiers>
          <isin value="US47103J1051"/>
        </identifiers>
        <balance>6150.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>84870.000000</valUSD>
        <pctVal>0.0116295339</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kailera Therapeutics SER B CVT PFD PP</name>
        <lei>N/A</lei>
        <title>KAILERA THERAPEUTICS SER B CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7TQ7JB6"/>
        </identifiers>
        <balance>36605.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>512470.000000</valUSD>
        <pctVal>0.0702225431</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KARDIUM INC SER D-5 CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>KARDIUM INC SER D-5 CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2GK4KE4"/>
        </identifiers>
        <balance>403778.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>330774.940000</valUSD>
        <pctVal>0.0453253019</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kardium Inc Series D-8 CVT PFD Stock PP</name>
        <lei>N/A</lei>
        <title>KARDIUM INC SERIES D-8 CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9ZSWM29"/>
        </identifiers>
        <balance>373263.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>241590.740000</valUSD>
        <pctVal>0.0331046035</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kardium Inc Ser D-6 CVT Pfd Stock PP</name>
        <lei>N/A</lei>
        <title>KARDIUM SERIES D6 CVT PFD STOCK PP</title>
        <cusip>TC0GUUWU8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5832431"/>
        </identifiers>
        <balance>556501.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>460448.930000</valUSD>
        <pctVal>0.0630942198</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KARTOS THERAPEUTICS SR C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS SR C CVT PFD STK PP</title>
        <cusip>TC1HQTAC7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="8997784"/>
        </identifiers>
        <balance>85928.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>485750.980000</valUSD>
        <pctVal>0.0665612995</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kartos Therapeutics SR D CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS SR D CVT PFD STK PP</title>
        <cusip>TC82Z0AE2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="10300524"/>
        </identifiers>
        <balance>27086.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>153117.160000</valUSD>
        <pctVal>0.0209812796</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KESTRA MEDICAL TECHNOLOGIES</name>
        <lei>N/A</lei>
        <title>KESTRA MEDICAL TECHNOLOGIES LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="BMG524411052"/>
        </identifiers>
        <balance>48776.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1293539.520000</valUSD>
        <pctVal>0.1772506385</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KODIAK SCIENCES INC</name>
        <lei>254900IXI5NI8C9OQE24</lei>
        <title>KODIAK SCIENCES INC</title>
        <cusip>50015M109</cusip>
        <identifiers>
          <isin value="US50015M1099"/>
        </identifiers>
        <balance>44034.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1231190.640000</valUSD>
        <pctVal>0.1687071200</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KRYSTAL BIOTECH INC</name>
        <lei>549300YONUY68210OE41</lei>
        <title>KRYSTAL BIOTECH INC</title>
        <cusip>501147102</cusip>
        <identifiers>
          <isin value="US5011471027"/>
        </identifiers>
        <balance>19742.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4867192.680000</valUSD>
        <pctVal>0.6669398167</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KYMERA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KYMERA THERAPEUTICS INC</title>
        <cusip>501575104</cusip>
        <identifiers>
          <isin value="US5015751044"/>
        </identifiers>
        <balance>74190.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5772723.900000</valUSD>
        <pctVal>0.7910226023</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KYVERNA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KYVERNA THERAPEUTICS INC</title>
        <cusip>501976104</cusip>
        <identifiers>
          <isin value="US5019761049"/>
        </identifiers>
        <balance>80673.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>758326.200000</valUSD>
        <pctVal>0.1039116324</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Kardium Inc Series D-7 CVT PFD Stock PP</name>
        <lei>N/A</lei>
        <title>Kardium, Inc. Series D-7 CVT Pfd Stock</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7NVVSV6"/>
        </identifiers>
        <balance>584117.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>378063.890000</valUSD>
        <pctVal>0.0518051941</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SAIL BIOMEDICINES SER B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>LARONDE SERIES B CVT PFD STOCK PP</title>
        <cusip>TC14DLDG5</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6589904"/>
        </identifiers>
        <balance>52537.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>75653.280000</valUSD>
        <pctVal>0.0103665887</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>LENZ THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>LENZ THERAPEUTICS INC</title>
        <cusip>52635N103</cusip>
        <identifiers>
          <isin value="US52635N1037"/>
        </identifiers>
        <balance>11100.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>177600.000000</valUSD>
        <pctVal>0.0243361049</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>LUMICKS TECH SER D CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>LUMICKS TECH SER D CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4O9ZGR5"/>
        </identifiers>
        <balance>221.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>119114.580000</valUSD>
        <pctVal>0.0163219871</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MADRIGAL PHARMACEUTICALS INC</name>
        <lei>549300CHIMT2EUSNJB60</lei>
        <title>MADRIGAL PHARMACEUTICALS INC</title>
        <cusip>558868105</cusip>
        <identifiers>
          <isin value="US5588681057"/>
        </identifiers>
        <balance>3980.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2317713.200000</valUSD>
        <pctVal>0.3175907177</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MBX BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>MBX BIOSCIENCES INC</title>
        <cusip>55287L101</cusip>
        <identifiers>
          <isin value="US55287L1017"/>
        </identifiers>
        <balance>36848.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1162185.920000</valUSD>
        <pctVal>0.1592515677</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MCKESSON CORP</name>
        <lei>549300WZWOM80UCFSF54</lei>
        <title>MCKESSON CORP</title>
        <cusip>58155Q103</cusip>
        <identifiers>
          <isin value="US58155Q1031"/>
        </identifiers>
        <balance>1800.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1476522.000000</valUSD>
        <pctVal>0.2023242918</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MEDIWOUND LTD</name>
        <lei>549300LJKCS74GRYKF90</lei>
        <title>MEDIWOUND LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="IL0011316309"/>
        </identifiers>
        <balance>8412.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>155285.520000</valUSD>
        <pctVal>0.0212784048</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MEDLINE INC-CL A</name>
        <lei>984500FAN6J1P8566D43</lei>
        <title>MEDLINE INC</title>
        <cusip>58507V107</cusip>
        <identifiers>
          <isin value="US58507V1070"/>
        </identifiers>
        <balance>22883.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>961086.000000</valUSD>
        <pctVal>0.1316953248</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MERCK &amp; CO. INC.</name>
        <lei>4YV9Y5M8S0BRK1RP0397</lei>
        <title>MERCK &amp; CO INC</title>
        <cusip>58933Y105</cusip>
        <identifiers>
          <isin value="US58933Y1055"/>
        </identifiers>
        <balance>126400.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>13304864.000000</valUSD>
        <pctVal>1.8231338145</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MIRUM PHARMACEUTICALS INC</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>MIRUM PHARMACEUTICALS INC</title>
        <cusip>604749101</cusip>
        <identifiers>
          <isin value="US6047491013"/>
        </identifiers>
        <balance>8500.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>671415.000000</valUSD>
        <pctVal>0.0920023978</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MOLINA HEALTHCARE INC</name>
        <lei>549300NQQCEQ46YHZ591</lei>
        <title>MOLINA HEALTHCARE INC</title>
        <cusip>60855R100</cusip>
        <identifiers>
          <isin value="US60855R1005"/>
        </identifiers>
        <balance>5877.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1019894.580000</valUSD>
        <pctVal>0.1397537244</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MONOPAR THERAPEUTICS INC</name>
        <lei>549300QJFAI7L6YHKG83</lei>
        <title>MONOPAR THERAPEUTICS INC</title>
        <cusip>61023L207</cusip>
        <identifiers>
          <isin value="US61023L2079"/>
        </identifiers>
        <balance>1085.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>70850.500000</valUSD>
        <pctVal>0.0097084752</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MONTE ROSA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>MONTE ROSA THERAPEUTICS INC</title>
        <cusip>61225M102</cusip>
        <identifiers>
          <isin value="US61225M1027"/>
        </identifiers>
        <balance>76377.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1197591.360000</valUSD>
        <pctVal>0.1641030907</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MOONLAKE IMMUNOTHERAPEUTICS</name>
        <lei>N/A</lei>
        <title>MOONLAKE IMMUNOTHERAPEUTICS</title>
        <cusip>61559X104</cusip>
        <identifiers>
          <isin value="KY61559X1045"/>
        </identifiers>
        <balance>44070.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>580842.600000</valUSD>
        <pctVal>0.0795914776</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MANUS BIO INC SERIES ONE-6 CVT PFD PP</name>
        <lei>N/A</lei>
        <title>Manus Bio, Inc Series One-6</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7PW0OO8"/>
        </identifiers>
        <balance>54498.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>163494.000000</valUSD>
        <pctVal>0.0224031933</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MIRUM PHARMACEUTICALS PIPE COMMIT PP</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>Mirum Pharmaceuticals Pipe Commit PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC97S2X58"/>
        </identifiers>
        <balance>4279.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>304198.390000</valUSD>
        <pctVal>0.0416835806</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NATERA INC</name>
        <lei>529900CQ3OZ0A0VYVU59</lei>
        <title>NATERA INC</title>
        <cusip>632307104</cusip>
        <identifiers>
          <isin value="US6323071042"/>
        </identifiers>
        <balance>34605.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7927659.450000</valUSD>
        <pctVal>1.0863082865</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NATIONAL RESILIENCE SR B CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>NATIONAL RESILIENCE SER B CVT PFD STOCK</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1NJ9YP1"/>
        </identifiers>
        <balance>54252.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>871829.640000</valUSD>
        <pctVal>0.1194647384</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NATIONAL RESILIENCE SR C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>NATIONAL RESILIENCE SER C CVT PFD STOCK</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1STY873"/>
        </identifiers>
        <balance>19224.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>308929.680000</valUSD>
        <pctVal>0.0423318980</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NEUROCRINE BIOSCIENCES INC</name>
        <lei>549300FECER0XBN49756</lei>
        <title>NEUROCRINE BIOSCIENCES INC</title>
        <cusip>64125C109</cusip>
        <identifiers>
          <isin value="US64125C1099"/>
        </identifiers>
        <balance>13551.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1921938.330000</valUSD>
        <pctVal>0.2633586303</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NEWAMSTERDAM PHARMA CO NV</name>
        <lei>984500B6549TF6E14D36</lei>
        <title>NEWAMSTERDAM PHARMA CO NV</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="NL00150012L7"/>
        </identifiers>
        <balance>6300.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>221004.000000</valUSD>
        <pctVal>0.0302836516</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NOVO-NORDISK A/S-SPONS ADR</name>
        <lei>549300DAQ1CVT6CXN342</lei>
        <title>NOVO NORDISK A/S</title>
        <cusip>670100205</cusip>
        <identifiers>
          <isin value="US6701002056"/>
        </identifiers>
        <balance>87900.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4472352.000000</valUSD>
        <pctVal>0.6128357390</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DK</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NURIX THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>NURIX THERAPEUTICS INC</title>
        <cusip>67080M103</cusip>
        <identifiers>
          <isin value="US67080M1036"/>
        </identifiers>
        <balance>86200.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1635214.000000</valUSD>
        <pctVal>0.2240694785</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NUTCRACKER THERA SER C CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>NUTCRACKER THERA SER C CVT PFD STOCK PP</title>
        <cusip>TC3WVBUQ2</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6730480"/>
        </identifiers>
        <balance>46567.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NUVALENT INC-A</name>
        <lei>N/A</lei>
        <title>NUVALENT INC</title>
        <cusip>670703107</cusip>
        <identifiers>
          <isin value="US6707031075"/>
        </identifiers>
        <balance>33589.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3378717.510000</valUSD>
        <pctVal>0.4629776105</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NUVATION BIO INC</name>
        <lei>N/A</lei>
        <title>NUVATION BIO INC</title>
        <cusip>67080N101</cusip>
        <identifiers>
          <isin value="US67080N1019"/>
        </identifiers>
        <balance>114600.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1026816.000000</valUSD>
        <pctVal>0.1407021500</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>OBSIDIAN THERAPEUTIC SR C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>OBSIDIAN THERAPEUTICS SR C CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0AIZJ47"/>
        </identifiers>
        <balance>222385.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>422064.490000</valUSD>
        <pctVal>0.0578344915</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Odyssey Therapeutics SER D CVT Pfd Stk PP</name>
        <lei>N/A</lei>
        <title>ODYSSEY THERAPEUTICS SER D CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9221RK3"/>
        </identifiers>
        <balance>24579.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>36990.660000</valUSD>
        <pctVal>0.0050687420</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ODYSSEY THERAPEUTICS SR B CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>ODYSSEY THERAPEUTICS SR B CVT PFD STK PP</title>
        <cusip>TC4CBMMO7</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7849359"/>
        </identifiers>
        <balance>50567.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>79895.860000</valUSD>
        <pctVal>0.0109479393</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ODYSSEY THERAPEUTICS SR C CVT PFD STK PP</name>
        <lei>N/A</lei>
        <title>ODYSSEY THERAPEUTICS SR C CVT PFD STK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0AM4J17"/>
        </identifiers>
        <balance>4902.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7377.360000</valUSD>
        <pctVal>0.0010109021</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Odyssey Therapeutics Warrants 6/32 WRT PP</name>
        <lei>N/A</lei>
        <title>ODYSSEY THERAPEUTICS WARRANTS 6/32 WRT PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2DVYMO9"/>
        </identifiers>
        <balance>7373.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>OLEMA PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>OLEMA PHARMACEUTICALS INC</title>
        <cusip>68062P106</cusip>
        <identifiers>
          <isin value="US68062P1066"/>
        </identifiers>
        <balance>50100.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1252500.000000</valUSD>
        <pctVal>0.1716270909</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ORCHESTRA BIOMED HOLDINGS INC</name>
        <lei>N/A</lei>
        <title>ORCHESTRA BIOMED HOLDINGS INC</title>
        <cusip>68572M106</cusip>
        <identifiers>
          <isin value="US68572M1062"/>
        </identifiers>
        <balance>24783.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>102849.450000</valUSD>
        <pctVal>0.0140932151</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ORIC PHARMACEUTICALS INC</name>
        <lei>54930033FJRNEYBW0L25</lei>
        <title>ORIC PHARMACEUTICALS INC</title>
        <cusip>68622P109</cusip>
        <identifiers>
          <isin value="US68622P1093"/>
        </identifiers>
        <balance>64559.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>528092.620000</valUSD>
        <pctVal>0.0723632735</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ORUKA THERAPEUTICS INC</name>
        <lei>529900TG7O4ESUDMGI54</lei>
        <title>ORUKA THERAPEUTICS INC</title>
        <cusip>687604108</cusip>
        <identifiers>
          <isin value="US6876041087"/>
        </identifiers>
        <balance>29726.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>900995.060000</valUSD>
        <pctVal>0.1234612064</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PALISADE BIO INC</name>
        <lei>549300W6LIDX3I5XXT34</lei>
        <title>PALISADE BIO INC</title>
        <cusip>696389402</cusip>
        <identifiers>
          <isin value="US6963894026"/>
        </identifiers>
        <balance>74955.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>176144.250000</valUSD>
        <pctVal>0.0241366269</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PAX LABS CLASS A COMMON PP</name>
        <lei>549300FKJA0AEKUHVG68</lei>
        <title>PAX LABS CLASS A COMMON PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6N68XA6"/>
        </identifiers>
        <balance>385684.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>119562.040000</valUSD>
        <pctVal>0.0163833015</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PENUMBRA INC</name>
        <lei>549300RGE06P3ECANU72</lei>
        <title>PENUMBRA INC</title>
        <cusip>70975L107</cusip>
        <identifiers>
          <isin value="US70975L1070"/>
        </identifiers>
        <balance>32116.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9985185.560000</valUSD>
        <pctVal>1.3682461872</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PHARVARIS NV</name>
        <lei>9845003BE146D3B75D32</lei>
        <title>PHARVARIS NV</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="NL00150005Y4"/>
        </identifiers>
        <balance>43958.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1219834.500000</valUSD>
        <pctVal>0.1671510152</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PRAXIS PRECISION MEDICINES I</name>
        <lei>N/A</lei>
        <title>PRAXIS PRECISION MEDICINES INC</title>
        <cusip>74006W207</cusip>
        <identifiers>
          <isin value="US74006W2070"/>
        </identifiers>
        <balance>13726.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4045601.240000</valUSD>
        <pctVal>0.5543590991</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PRELUDE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>PRELUDE THERAPEUTICS INC</title>
        <cusip>74065P101</cusip>
        <identifiers>
          <isin value="US74065P1012"/>
        </identifiers>
        <balance>42748.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>123969.200000</valUSD>
        <pctVal>0.0169872041</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROCEPT BIOROBOTICS CORP</name>
        <lei>N/A</lei>
        <title>PROCEPT BIOROBOTICS CORP</title>
        <cusip>74276L105</cusip>
        <identifiers>
          <isin value="US74276L1052"/>
        </identifiers>
        <balance>21641.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>680825.860000</valUSD>
        <pctVal>0.0932919455</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROFOUNDBIO ESCROW FUND PAYMENT PP</name>
        <lei>N/A</lei>
        <title>PROFOUNBIO ESCROW FUND PAYMENT</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7U0XRJ8"/>
        </identifiers>
        <balance>33627.010000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>31945.660000</valUSD>
        <pctVal>0.0043774377</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROFOUNDBIO EXPENSE FUND PAYMENT PP</name>
        <lei>N/A</lei>
        <title>PROFOUNDBIO EXPENSE FUND PYMT</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC23PZLJ7"/>
        </identifiers>
        <balance>112.090000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>22.420000</valUSD>
        <pctVal>0.0000030722</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROGNOMIQ INC CL A Common  PP</name>
        <lei>N/A</lei>
        <title>PROGNOMIQ INC PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC1WY4OI2"/>
        </identifiers>
        <balance>27338.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4100.700000</valUSD>
        <pctVal>0.0005619092</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PROTAGONIST THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>PROTAGONIST THERAPEUTICS INC</title>
        <cusip>74366E102</cusip>
        <identifiers>
          <isin value="US74366E1029"/>
        </identifiers>
        <balance>58543.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5113145.620000</valUSD>
        <pctVal>0.7006421620</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RADNET INC</name>
        <lei>529900RECG94V2IZJ970</lei>
        <title>RADNET INC</title>
        <cusip>750491102</cusip>
        <identifiers>
          <isin value="US7504911022"/>
        </identifiers>
        <balance>10400.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>742040.000000</valUSD>
        <pctVal>0.1016799733</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RAPPORT THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>RAPPORT THERAPEUTICS INC</title>
        <cusip>75383L102</cusip>
        <identifiers>
          <isin value="US75383L1026"/>
        </identifiers>
        <balance>41015.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1244395.100000</valUSD>
        <pctVal>0.1705164957</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Reflexion Med CVT Note issued 082725 PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MED CVT NOTE ISSUED 082725 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3F1Y6H9"/>
        </identifiers>
        <balance>12142.500000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>18942.300000</valUSD>
        <pctVal>0.0025956182</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2026-07-11</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>15.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>REFLEXION MEDICAL INC</name>
              <title>REFLEXION MEDICAL INC</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Reflexion Med CVT Note issued 081325 PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MED CVT PROM NOTE 081325 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC09D0VT3"/>
        </identifiers>
        <balance>12142.500000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>19063.730000</valUSD>
        <pctVal>0.0026122575</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2026-07-11</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>15.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>REFLEXION MEDICAL INC</name>
              <title>REFLEXION MEDICAL INC</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Reflexion Med CVT Note issued 072525 PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL CVT PROM NOTE PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4FJHLV8"/>
        </identifiers>
        <balance>12142.500000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>19185.150000</valUSD>
        <pctVal>0.0026288954</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2026-08-11</maturityDt>
          <couponKind>None</couponKind>
          <annualizedRt>0.0000000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>N</isMandatoryConvrtbl>
          <isContngtConvrtbl>N</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>REFLEXION MEDICAL INC PP</name>
              <title>REFLEXION MEDICAL INC PP</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal ID" value="Internal ID"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REFLEXION MEDICAL INC CVT PFD SR D-X PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL INC CVT</title>
        <cusip>TC70GKL85</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="5147983"/>
        </identifiers>
        <balance>51079.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23496.340000</valUSD>
        <pctVal>0.0032196475</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REFLEXION MEDICAL INC CVT PFD SR C-X PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL INC CVT PFD SR C PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <ticker value="TC37G1B6"/>
        </identifiers>
        <balance>150708.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>61790.280000</valUSD>
        <pctVal>0.0084669749</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REFLEXION MEDICAL SER F CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL INC PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC58LDJM2"/>
        </identifiers>
        <balance>83280.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>29980.800000</valUSD>
        <pctVal>0.0041081976</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REFLEXION MEDICAL INC CVT PFD SR E-X PP</name>
        <lei>N/A</lei>
        <title>REFLEXION MEDICAL INC SR E CVT PFD PP</title>
        <cusip>TC9L8ZXJ6</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="7579526"/>
        </identifiers>
        <balance>83857.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>47798.490000</valUSD>
        <pctVal>0.0065497132</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REGENERON PHARMACEUTICALS</name>
        <lei>549300RCBFWIRX3HYQ56</lei>
        <title>REGENERON PHARMACEUTICALS INC</title>
        <cusip>75886F107</cusip>
        <identifiers>
          <isin value="US75886F1075"/>
        </identifiers>
        <balance>24187.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>18669219.690000</valUSD>
        <pctVal>2.5581986939</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RELAY THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>RELAY THERAPEUTICS INC</title>
        <cusip>75943R102</cusip>
        <identifiers>
          <isin value="US75943R1023"/>
        </identifiers>
        <balance>66419.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>561904.740000</valUSD>
        <pctVal>0.0769964678</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REPLIGEN CORP</name>
        <lei>54930006QJ0T5AUO1E71</lei>
        <title>REPLIGEN CORP</title>
        <cusip>759916109</cusip>
        <identifiers>
          <isin value="US7599161095"/>
        </identifiers>
        <balance>12600.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2064636.000000</valUSD>
        <pctVal>0.2829121520</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REPLIMUNE GROUP INC</name>
        <lei>549300AY704NEIRC4K64</lei>
        <title>REPLIMUNE GROUP INC</title>
        <cusip>76029N106</cusip>
        <identifiers>
          <isin value="US76029N1063"/>
        </identifiers>
        <balance>94567.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>919191.240000</valUSD>
        <pctVal>0.1259545856</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REVOLUTION MEDICINES INC WTS 12/26</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>REVOLUTION MEDICINES INC</title>
        <cusip>76155X118</cusip>
        <identifiers>
          <isin value="US76155X1182"/>
        </identifiers>
        <balance>11096.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>10429.130000</valUSD>
        <pctVal>0.0014290788</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REVOLUTION MEDICINES INC</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>REVOLUTION MEDICINES INC</title>
        <cusip>76155X100</cusip>
        <identifiers>
          <isin value="US76155X1000"/>
        </identifiers>
        <balance>87505.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6969773.250000</valUSD>
        <pctVal>0.9550514227</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>REVVITY INC</name>
        <lei>549300IKL1SDPFI7N655</lei>
        <title>REVVITY INC</title>
        <cusip>714046109</cusip>
        <identifiers>
          <isin value="US7140461093"/>
        </identifiers>
        <balance>18117.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1752819.750000</valUSD>
        <pctVal>0.2401847142</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RHYTHM PHARMACEUTICALS INC</name>
        <lei>529900JPNWXQ8DPLA551</lei>
        <title>RHYTHM PHARMACEUTICALS INC</title>
        <cusip>76243J105</cusip>
        <identifiers>
          <isin value="US76243J1051"/>
        </identifiers>
        <balance>19767.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2115859.680000</valUSD>
        <pctVal>0.2899312108</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RING THERAPEUTICS INC PP</name>
        <lei>N/A</lei>
        <title>RING THERAPEUTICS INC PP</title>
        <cusip>TC4CR9CB8</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="6123622"/>
        </identifiers>
        <balance>13073.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>60135.800000</valUSD>
        <pctVal>0.0082402654</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROCKET PHARMACEUTICALS INC</name>
        <lei>549300R7VV82YUIN4Y93</lei>
        <title>ROCKET PHARMACEUTICALS INC</title>
        <cusip>77313F106</cusip>
        <identifiers>
          <isin value="US77313F1066"/>
        </identifiers>
        <balance>51403.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>180424.530000</valUSD>
        <pctVal>0.0247231435</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROIVANT SCIENCES LTD</name>
        <lei>549300DL466NY5J6U724</lei>
        <title>ROIVANT SCIENCES LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="BMG762791017"/>
        </identifiers>
        <balance>203518.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4416340.600000</valUSD>
        <pctVal>0.6051606303</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROYALTY PHARMA PLC- CL A</name>
        <lei>549300FGFN7VOK8BZR03</lei>
        <title>ROYALTY PHARMA PLC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="GB00BMVP7Y09"/>
        </identifiers>
        <balance>43300.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1673112.000000</valUSD>
        <pctVal>0.2292625511</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SALUDA MEDICAL INC</name>
        <lei>N/A</lei>
        <title>SALUDA MEDICAL INC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="AU0000432114"/>
        </identifiers>
        <balance>234087.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="AUD" exchangeRt="1.498464"/>
        <valUSD>222610.590000</valUSD>
        <pctVal>0.0305037988</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Saluda Medical Inc Lockup Shs CDI PP</name>
        <lei>N/A</lei>
        <title>SALUDA MEDICAL INC PP restricted cdi</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC2CX8OG1"/>
        </identifiers>
        <balance>189460.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="AUD" exchangeRt="1.498464"/>
        <valUSD>180171.490000</valUSD>
        <pctVal>0.0246884700</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>AU</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SANA BIOTECHNOLOGY INC</name>
        <lei>N/A</lei>
        <title>SANA BIOTECHNOLOGY INC</title>
        <cusip>799566104</cusip>
        <identifiers>
          <isin value="US7995661045"/>
        </identifiers>
        <balance>29400.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>119658.000000</valUSD>
        <pctVal>0.0163964506</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SARTORIUS AG-VORZUG PREF</name>
        <lei>529900EQV2DY4FOAMU38</lei>
        <title>SARTORIUS AG</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="DE0007165631"/>
        </identifiers>
        <balance>5999.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.850919"/>
        <valUSD>1727499.320000</valUSD>
        <pctVal>0.2367151160</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SCHOLAR ROCK HOLDING CORP</name>
        <lei>549300Z1FLPGL4OWJ459</lei>
        <title>SCHOLAR ROCK HOLDING CORP</title>
        <cusip>80706P103</cusip>
        <identifiers>
          <isin value="US80706P1030"/>
        </identifiers>
        <balance>103232.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4547369.600000</valUSD>
        <pctVal>0.6231152220</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SCRIBE THERA SER B CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>SCRIBE THERA SER B CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC3QFGOY2"/>
        </identifiers>
        <balance>45881.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>277639.700000</valUSD>
        <pctVal>0.0380443066</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SEAPORT THERAPEUTICS SER B CVT PFD PP</name>
        <lei>N/A</lei>
        <title>SEAPORT THERAPEUTICS SER B CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6RVVDR3"/>
        </identifiers>
        <balance>113620.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>539695.000000</valUSD>
        <pctVal>0.0739531200</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SENSORION SA</name>
        <lei>969500P0W8XJ9CGZDP97</lei>
        <title>SENSORION SA</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="FR0012596468"/>
        </identifiers>
        <balance>486286.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.850919"/>
        <valUSD>191728.480000</valUSD>
        <pctVal>0.0262720968</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>FR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SHATTUCK LABS INC</name>
        <lei>N/A</lei>
        <title>SHATTUCK LABS INC</title>
        <cusip>82024L103</cusip>
        <identifiers>
          <isin value="US82024L1035"/>
        </identifiers>
        <balance>91889.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>335394.850000</valUSD>
        <pctVal>0.0459583572</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SIONNA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SIONNA THERAPEUTICS INC</title>
        <cusip>829401108</cusip>
        <identifiers>
          <isin value="US8294011080"/>
        </identifiers>
        <balance>38965.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1603020.100000</valUSD>
        <pctVal>0.2196580250</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SOLENO THERAPEUTICS INC</name>
        <lei>5493003LCY77N7FXK844</lei>
        <title>SOLENO THERAPEUTICS INC</title>
        <cusip>834203309</cusip>
        <identifiers>
          <isin value="US8342033094"/>
        </identifiers>
        <balance>6791.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>314423.300000</valUSD>
        <pctVal>0.0430846757</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SOMALOGIC INC WTS 8/26</name>
        <lei>549300D3W3Q8CN30YO25</lei>
        <title>SOMALOGIC INC</title>
        <cusip>83444K113</cusip>
        <identifiers>
          <isin value="US83444K1135"/>
        </identifiers>
        <balance>4962.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.000000</valUSD>
        <pctVal>0.0000000000</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SONOVA HOLDING AG-REG</name>
        <lei>5299004A0QNX7FBNHS61</lei>
        <title>SONOVA HOLDING AG</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="CH0012549785"/>
        </identifiers>
        <balance>5348.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="CHF" exchangeRt="0.792100"/>
        <valUSD>1383349.920000</valUSD>
        <pctVal>0.1895571436</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SPAC PCSC Freenome PIPE COMMIT PP</name>
        <lei>254900QDTSQ6S0QOCS43</lei>
        <title>SPAC PCSC FREENOME PIPE COMMIT PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC8BJ37B4"/>
        </identifiers>
        <balance>26090.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>305957.430000</valUSD>
        <pctVal>0.0419246177</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Spyre Therapeutics Inc</name>
        <lei>52990017AIJPRH3HQH40</lei>
        <title>SPYRE THERAPEUTICS INC</title>
        <cusip>00773J202</cusip>
        <identifiers>
          <isin value="US00773J2024"/>
        </identifiers>
        <balance>54447.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1783683.720000</valUSD>
        <pctVal>0.2444139305</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>STRUCTURE THERAPEUTICS INC ADR</name>
        <lei>N/A</lei>
        <title>STRUCTURE THERAPEUTICS INC</title>
        <cusip>86366E106</cusip>
        <identifiers>
          <isin value="US86366E1064"/>
        </identifiers>
        <balance>63911.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4445010.050000</valUSD>
        <pctVal>0.6090891367</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>STRYKER CORP</name>
        <lei>5493002F0SC4JTBU5137</lei>
        <title>STRYKER CORP</title>
        <cusip>863667101</cusip>
        <identifiers>
          <isin value="US8636671013"/>
        </identifiers>
        <balance>73042.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>25672071.740000</valUSD>
        <pctVal>3.5177828258</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SUMMIT THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SUMMIT THERAPEUTICS INC</title>
        <cusip>86627T108</cusip>
        <identifiers>
          <isin value="US86627T1088"/>
        </identifiers>
        <balance>441950.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7729705.500000</valUSD>
        <pctVal>1.0591831283</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>T. Rowe Price Government Reserve Fund</name>
        <lei>5493002Y0IYARJVQ5N24</lei>
        <title>T. Rowe Price Government Reserve Fund</title>
        <cusip>76105Y109</cusip>
        <identifiers>
          <isin value="US76105Y1091"/>
        </identifiers>
        <balance>3526241.240000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3526241.240000</valUSD>
        <pctVal>0.4831924357</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TARSUS PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>TARSUS PHARMACEUTICALS INC</title>
        <cusip>87650L103</cusip>
        <identifiers>
          <isin value="US87650L1035"/>
        </identifiers>
        <balance>21977.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1799476.760000</valUSD>
        <pctVal>0.2465780131</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TENAX THERAPEUTICS PRE FUND WTS PIPE PP</name>
        <lei>549300J03O6B1IJ2B606</lei>
        <title>TENAX THERAPEUTICS PRE FUNDED WTS PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC5GWXEZ4"/>
        </identifiers>
        <balance>101916.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1179531.450000</valUSD>
        <pctVal>0.1616283843</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TENET HEALTHCARE CORP</name>
        <lei>0W9AIBT6U6ADJ2I8HK17</lei>
        <title>TENET HEALTHCARE CORP</title>
        <cusip>88033G407</cusip>
        <identifiers>
          <isin value="US88033G4073"/>
        </identifiers>
        <balance>35585.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7071451.200000</valUSD>
        <pctVal>0.9689841099</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TERNS PHARMACEUTICALS INC</name>
        <lei>254900S1ZDQMF4MYP709</lei>
        <title>TERNS PHARMACEUTICALS INC</title>
        <cusip>880881107</cusip>
        <identifiers>
          <isin value="US8808811074"/>
        </identifiers>
        <balance>28721.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1160328.400000</valUSD>
        <pctVal>0.1589970361</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TESSERA THERAPEUTICS SER D CVT PFD PP</name>
        <lei>N/A</lei>
        <title>TESSERA THERAPEUTICS SER D CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC6AR2E49"/>
        </identifiers>
        <balance>17248.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>89344.640000</valUSD>
        <pctVal>0.0122426832</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TEVA PHARMACEUTICAL-SP ADR</name>
        <lei>549300BAFGM4RC74ZJ94</lei>
        <title>TEVA PHARMACEUTICAL INDUSTRIES LTD</title>
        <cusip>881624209</cusip>
        <identifiers>
          <isin value="US8816242098"/>
        </identifiers>
        <balance>46400.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1448144.000000</valUSD>
        <pctVal>0.1984357221</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>THERMO FISHER SCIENTIFIC INC</name>
        <lei>HCHV7422L5HDJZCRFL38</lei>
        <title>THERMO FISHER SCIENTIFIC INC</title>
        <cusip>883556102</cusip>
        <identifiers>
          <isin value="US8835561023"/>
        </identifiers>
        <balance>53863.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>31210915.350000</valUSD>
        <pctVal>4.2767573691</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>THIRD ARC BIO SER A CVT PFD PP</name>
        <lei>N/A</lei>
        <title>THIRD ARC BIO SER A CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC5WFUTE5"/>
        </identifiers>
        <balance>203148.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>427464.020000</valUSD>
        <pctVal>0.0585743762</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Treeline Bio Common WTS 8/35 PP</name>
        <lei>N/A</lei>
        <title>TREELINE BIO COMMON WTS 8.35 PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC8LDBAV2"/>
        </identifiers>
        <balance>2604.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>18975.350000</valUSD>
        <pctVal>0.0026001470</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TREELINE BIO SER A CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>TREELINE BIO SER A CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC0U9C2T7"/>
        </identifiers>
        <balance>106061.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>772866.510000</valUSD>
        <pctVal>0.1059040565</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TREELINE BIO SER A-1 CVT PFD STOCK PP</name>
        <lei>N/A</lei>
        <title>TREELINE BIO SER A-1 CVT PFD STOCK PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC51XS4U9"/>
        </identifiers>
        <balance>123059.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>896730.930000</valUSD>
        <pctVal>0.1228769028</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Treeline Bio SER A-2 CVT PFD PP</name>
        <lei>N/A</lei>
        <title>TREELINE BIO SER A-2 NV CVT PFD PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9QDVLP7"/>
        </identifiers>
        <balance>17362.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>126516.890000</valUSD>
        <pctVal>0.0173363080</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TENAX THERAPEUTICS NEW WTS 8/29 PIPE PP</name>
        <lei>549300J03O6B1IJ2B606</lei>
        <title>Tenax Therapeutics, Inc</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC9A9ADO5"/>
        </identifiers>
        <balance>53640.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>141297.420000</valUSD>
        <pctVal>0.0193616488</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TESSERA THERAPEUTICS SER C' CVT PFD PP</name>
        <lei>N/A</lei>
        <title>Tessera Therapeutics, Inc. Series C</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC7M24T72"/>
        </identifiers>
        <balance>30439.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>157674.020000</valUSD>
        <pctVal>0.0216056953</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UCB SA</name>
        <lei>2138008J191VLSGY5A09</lei>
        <title>UCB SA</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="BE0003739530"/>
        </identifiers>
        <balance>1064.000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.850919"/>
        <valUSD>296458.700000</valUSD>
        <pctVal>0.0406230293</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ULTRAGENYX PHARMACEUTICAL INC</name>
        <lei>529900EV44GVDN1DCX77</lei>
        <title>ULTRAGENYX PHARMACEUTICAL INC</title>
        <cusip>90400D108</cusip>
        <identifiers>
          <isin value="US90400D1081"/>
        </identifiers>
        <balance>29021.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>667483.000000</valUSD>
        <pctVal>0.0914636052</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UNIQURE NV</name>
        <lei>724500RPCTZLFYJZ3S98</lei>
        <title>UNIQURE NV</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="NL0010696654"/>
        </identifiers>
        <balance>8566.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>204984.380000</valUSD>
        <pctVal>0.0280885212</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UNITED THERAPEUTICS CORP</name>
        <lei>5299005C4HZL4UWROC14</lei>
        <title>UNITED THERAPEUTICS CORP</title>
        <cusip>91307C102</cusip>
        <identifiers>
          <isin value="US91307C1027"/>
        </identifiers>
        <balance>13940.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6792265.000000</valUSD>
        <pctVal>0.9307278901</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UNITEDHEALTH GROUP INC</name>
        <lei>549300GHBMY8T5GXDE41</lei>
        <title>UNITEDHEALTH GROUP INC</title>
        <cusip>91324P102</cusip>
        <identifiers>
          <isin value="US91324P1021"/>
        </identifiers>
        <balance>73104.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>24132361.440000</valUSD>
        <pctVal>3.3067999918</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UROGEN PHARMA LTD</name>
        <lei>549300C0YCX7CG2G5D50</lei>
        <title>UROGEN PHARMA LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="IL0011407140"/>
        </identifiers>
        <balance>29300.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>686206.000000</valUSD>
        <pctVal>0.0940291733</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VAXCYTE INC</name>
        <lei>254900M7NMHTGASX8D95</lei>
        <title>VAXCYTE INC</title>
        <cusip>92243G108</cusip>
        <identifiers>
          <isin value="US92243G1085"/>
        </identifiers>
        <balance>27617.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1274248.380000</valUSD>
        <pctVal>0.1746072196</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VERA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>VERA THERAPEUTICS INC</title>
        <cusip>92337R101</cusip>
        <identifiers>
          <isin value="US92337R1014"/>
        </identifiers>
        <balance>119441.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6048492.240000</valUSD>
        <pctVal>0.8288104809</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VERILY LIFE SCIENCES LLC SER B UNITS PP</name>
        <lei>5493003ZYK1Z7M670M44</lei>
        <title>VERILY LIFE SCIENCES LLC SER B UNITS PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="TC4V69U94"/>
        </identifiers>
        <balance>5220.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>172260.000000</valUSD>
        <pctVal>0.0236043774</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VERTEX PHARMACEUTICALS INC</name>
        <lei>54930015RAQRRZ5ZGJ91</lei>
        <title>VERTEX PHARMACEUTICALS INC</title>
        <cusip>92532F100</cusip>
        <identifiers>
          <isin value="US92532F1003"/>
        </identifiers>
        <balance>26940.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>12213518.400000</valUSD>
        <pctVal>1.6735893271</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VIRIDIAN THERAPEUTICS INC</name>
        <lei>549300C775BNYF550E70</lei>
        <title>VIRIDIAN THERAPEUTICS INC</title>
        <cusip>92790C104</cusip>
        <identifiers>
          <isin value="US92790C1045"/>
        </identifiers>
        <balance>40141.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1249187.920000</valUSD>
        <pctVal>0.1711732444</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VOYAGER THERAPEUTICS INC</name>
        <lei>54930082S4XVR0ZWCC74</lei>
        <title>VOYAGER THERAPEUTICS INC</title>
        <cusip>92915B106</cusip>
        <identifiers>
          <isin value="US92915B1061"/>
        </identifiers>
        <balance>23076.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>90688.680000</valUSD>
        <pctVal>0.0124268538</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>WATERS CORP</name>
        <lei>5T547R1474YC9HOD8Q74</lei>
        <title>WATERS CORP</title>
        <cusip>941848103</cusip>
        <identifiers>
          <isin value="US9418481035"/>
        </identifiers>
        <balance>4800.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1823184.000000</valUSD>
        <pctVal>0.2498265597</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>WAVE LIFE SCIENCES LTD</name>
        <lei>54930070006GPKFYZ813</lei>
        <title>WAVE LIFE SCIENCES LTD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="SG9999014716"/>
        </identifiers>
        <balance>92045.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1564765.000000</valUSD>
        <pctVal>0.2144160198</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>SG</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>XENCOR INC</name>
        <lei>549300V5IF65437JKG30</lei>
        <title>XENCOR INC</title>
        <cusip>98401F105</cusip>
        <identifiers>
          <isin value="US98401F1057"/>
        </identifiers>
        <balance>33300.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>509823.000000</valUSD>
        <pctVal>0.0698598310</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>XENON PHARMACEUTICALS INC</name>
        <lei>549300XV44Q9Z1MIPQ03</lei>
        <title>XENON PHARMACEUTICALS INC</title>
        <cusip>98420N105</cusip>
        <identifiers>
          <isin value="CA98420N1050"/>
        </identifiers>
        <balance>8100.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>363042.000000</valUSD>
        <pctVal>0.0497467803</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ZAI LAB LTD ADR</name>
        <lei>549300P2UYQ9U5LY1T58</lei>
        <title>ZAI LAB LTD</title>
        <cusip>98887Q104</cusip>
        <identifiers>
          <isin value="US98887Q1040"/>
        </identifiers>
        <balance>30477.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>537614.280000</valUSD>
        <pctVal>0.0736680039</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ZOETIS INC</name>
        <lei>549300HD9Q1LOC9KLJ48</lei>
        <title>ZOETIS INC</title>
        <cusip>98978V103</cusip>
        <identifiers>
          <isin value="US98978V1035"/>
        </identifiers>
        <balance>9000.000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1132380.000000</valUSD>
        <pctVal>0.1551673335</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2026-02-04</ncom:dateSigned>
      <ncom:nameOfApplicant>T. ROWE PRICE EQUITY SERIES, INC.</ncom:nameOfApplicant>
      <ncom:signature>/s/ Alan Dupski</ncom:signature>
      <ncom:signerName>Alan Dupski</ncom:signerName>
      <ncom:title>Treasurer &amp; Vice President</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
