FEDERATED HERMES WORLD INVESTMENT SERIES, INC.

4000 Ericsson Drive
Warrendale, Pennsylvania 15086-7561

January 29, 2021

EDGAR Operations Branch
U.S. Securities and Exchange Commission
Division of Investment Management
100 F Street, N.E.
Washington, DC 20549

RE:	FEDERATED HERMES WORLD INVESTMENT SERIES, INC. (the “Registrant”)
	Federated Hermes Emerging Market Debt Fund Class A Shares Class C Shares Institutional Shares Federated Hermes International Leaders Fund Class A Shares Class B Shares Class C Shares Institutional Shares Class R Shares Class R6 Shares Federated Hermes International Small-Mid Company Fund Class A Shares Class C Shares Institutional Shares (“collectively, the Funds”)
	1933 Act File No. 33-52149
	1940 Act File No. 811-7141

Dear Sir or Madam:

Pursuant to Rule 497(j) under the Securities Act of 1933, the above-named Registrant hereby certifies that the definitive forms of Prospectuses and Statements of Additional Information dated January 31, 2021, that would have otherwise been filed under Rule 497(c), do not differ from the forms of Prospectuses and Statements of Additional Information contained in the Registration Statement for the Funds which was electronically filed pursuant to Rule 485(b) as Post-Effective Amendment No. 78 on January 28, 2021.

If you have any questions on the enclosed material, please contact me at (412) 288-1474.

Very truly yours,

/s/George F. Magera
George F. Magera
Assistant Secretary