Segment Information - Schedule of Significant Expense Category (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Segment Reporting [Abstract]
Payroll and benefits	$ 129,228	$ 123,056	$ 124,130
Variable research and development expenses	27,342	28,228	29,482
Professional fees	20,055	22,148	21,524
Temporary labor services and consulting expenses	14,264	13,577	17,276
Facilities costs	11,853	12,347	11,205
Amortization and depreciation	10,076	10,144	9,265
Other expenses	9,651	7,962	8,306
Total adjusted operating expenses	$ 222,469	$ 217,462	$ 221,188