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Fair Value of Financial Instruments (Details) - USD ($)
Dec. 31, 2020
Dec. 31, 2019
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities $ 441,186,000 $ 363,542,000
Equity method investment, ownership percentage 25.00% 25.00%
Equity method investment $ 2,800,000 $ 3,600,000
Money market funds    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 32,815,000 10,065,000
U.S. Government bonds and notes    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 169,880,000 39,086,000
Corporate notes, bonds and commercial paper    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 238,491,000 314,391,000
Recurring basis    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 441,186,000 363,542,000
Recurring basis | Money market funds    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 32,815,000 10,065,000
Recurring basis | U.S. Government bonds and notes    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 169,880,000 39,086,000
Recurring basis | Corporate notes, bonds and commercial paper    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 238,491,000 314,391,000
Recurring basis | Quoted market prices in active markets (Level 1)    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 32,815,000 10,065,000
Recurring basis | Quoted market prices in active markets (Level 1) | Money market funds    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 32,815,000 10,065,000
Recurring basis | Quoted market prices in active markets (Level 1) | U.S. Government bonds and notes    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 0 0
Recurring basis | Quoted market prices in active markets (Level 1) | Corporate notes, bonds and commercial paper    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 0 0
Recurring basis | Significant other observable inputs (Level 2)    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 408,371,000 353,477,000
Recurring basis | Significant other observable inputs (Level 2) | Money market funds    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 0 0
Recurring basis | Significant other observable inputs (Level 2) | U.S. Government bonds and notes    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 169,880,000 39,086,000
Recurring basis | Significant other observable inputs (Level 2) | Corporate notes, bonds and commercial paper    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 238,491,000 314,391,000
Recurring basis | Significant unobservable inputs (Level 3)    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 0 0
Recurring basis | Significant unobservable inputs (Level 3) | Money market funds    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 0 0
Recurring basis | Significant unobservable inputs (Level 3) | U.S. Government bonds and notes    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities 0 0
Recurring basis | Significant unobservable inputs (Level 3) | Corporate notes, bonds and commercial paper    
Financial assets subject to fair value measurements and the necessary disclosures    
Total available-for-sale securities $ 0 $ 0