CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Revenue
Revenue	$ 56,915	$ 57,399	$ 180,834	$ 164,080
Cost of revenue
Cost of product revenue	9,661	7,108	30,281	17,845
Cost of contract and other revenue	1,267	2,450	4,000	8,268
Amortization of acquired intangible assets	4,336	3,016	13,016	10,686
Cost of revenue	15,264	12,574	47,297	36,799
Gross profit	41,651	44,825	133,537	127,281
Operating expenses:
Research and development	33,733	41,486	105,085	119,995
Sales, general and administrative	20,182	26,521	64,387	76,835
Amortization of acquired intangible assets	236	170	832	2,409
Restructuring charges	0	1,374	836	4,233
Change in fair value of earn-out liability	0	0	(1,800)	0
Impairment (recovery) of assets held for sale	0	(1,853)	0	15,137
Total operating expenses	54,151	67,698	169,340	218,609
Operating loss	(12,500)	(22,873)	(35,803)	(91,328)
Interest income and other income (expense), net	3,464	6,727	14,435	21,112
Interest expense	(2,586)	(2,497)	(7,721)	(7,302)
Interest and other income (expense), net	878	4,230	6,714	13,810
Loss before income taxes	(11,622)	(18,643)	(29,089)	(77,518)
Provision for (benefit from) income taxes	1,157	(1,312)	2,454	3,369
Net loss	$ (12,779)	$ (17,331)	$ (31,543)	$ (80,887)
Net loss per share:
Earnings per share, basic	$ (0.11)	$ (0.16)	$ (0.28)	$ (0.73)
Earnings per share, diluted	$ (0.11)	$ (0.16)	$ (0.28)	$ (0.73)
Weighted-average shares used in per share calculation:
Basic (in shares)	113,828	111,315	113,437	110,633
Diluted (in shares)	113,828	111,315	113,437	110,633
Royalties
Revenue
Revenue	$ 16,602	$ 19,448	$ 53,253	$ 71,351
Product revenue
Revenue
Revenue	29,769	21,377	92,222	46,372
Contract and other revenue
Revenue
Revenue	$ 10,544	$ 16,574	$ 35,359	$ 46,357