CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended				6 Months Ended
	Jun. 30, 2020		Jun. 30, 2019		Jun. 30, 2020	Jun. 30, 2019
Revenue
Revenue	$ 59,930		$ 58,297		$ 123,919	$ 106,681
Cost of revenue
Cost of product revenue	10,277	[1]	6,310	[1]	20,620	10,737
Cost of contract and other revenue	1,535		2,910		2,733	5,818
Amortization of acquired intangible assets	4,336		3,807		8,680	7,670
Cost of revenue	16,148		13,027		32,033	24,225
Gross profit	43,782		45,270		91,886	82,456
Operating expenses:
Research and development	34,688	[1]	37,890	[1]	71,352	78,509
Sales, general and administrative	21,310	[1]	23,794	[1]	44,205	50,314
Amortization of acquired intangible assets	248		1,114		596	2,239
Restructuring charges	0		2,528		836	2,859
Change in fair value of earn-out liability			0		(1,800)	0
Impairment of assets held for sale	0		16,990		0	16,990
Total operating expenses	56,246		82,316		115,189	150,911
Operating loss	(12,464)		(37,046)		(23,303)	(68,455)
Interest income and other income (expense), net	4,597		6,972		10,971	14,385
Interest expense	(2,580)		(2,534)		(5,135)	(4,805)
Interest and other income (expense), net	2,017		4,438		5,836	9,580
Loss before income taxes	(10,447)		(32,608)		(17,467)	(58,875)
Provision for income taxes	334		4,372		1,297	4,681
Net loss	$ (10,781)		$ (36,980)		$ (18,764)	$ (63,556)
Net loss per share:
Earnings per share, basic	$ (0.09)		$ (0.33)		$ (0.17)	$ (0.58)
Earnings per share, diluted	$ (0.09)		$ (0.33)		$ (0.17)	$ (0.58)
Weighted average shares used in per share calculation:
Basic (in shares)	113,572		110,875		113,240	110,287
Diluted (in shares)	113,572		110,875		113,240	110,287
Royalties
Revenue
Revenue	$ 16,957		$ 27,050		$ 36,651	$ 51,903
Product revenue
Revenue
Revenue	31,725		16,031		62,453	24,995
Contract and other revenue
Revenue
Revenue	$ 11,248		$ 15,216		$ 24,815	$ 29,783

[1] Includes stock-based compensation: Cost of product revenue$—  $1  $—  $2  Research and development$2,515  $3,058  $5,128  $6,268  Sales, general and administrative$4,192  $4,021  $7,651  $7,999