CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2017	Dec. 31, 2016
Current assets:
Cash and cash equivalents	$ 225,844	$ 135,294
Marketable securities	103,532	36,888
Accounts receivable	25,892	21,099
Prepaids and other current assets	11,317	17,867
Inventories	5,159	5,633
Total current assets	371,744	216,781
Intangible Assets, Net	91,722	132,388
Goodwill	209,661	204,794
Property, plant and equipment, net	54,303	58,442
Deferred tax assets	159,099	168,342
Other assets	4,543	2,749
Total assets	891,072	783,496
Current liabilities:
Accounts payable	9,614	9,793
Accrued salaries and benefits	17,091	14,177
Convertible Notes Payable, Current	78,451	0
Deferred Revenue	18,272	16,932
Other current liabilities	9,414	10,399
Total current liabilities	132,842	51,301
Convertible notes, long-term	135,447	126,167
Long-term imputed financing obligation	37,262	38,029
Deferred tax liabilities	9,830	11,600
Other long-term liabilities	4,107	3,617
Total liabilities	319,488	230,714
Commitments and contingencies (Notes 11 and 17)
Stockholders’ equity:
Convertible preferred stock, $.001 par value: Authorized: 5,000,000 shares; Issued and outstanding: no shares at December 31, 2017 and December 31, 2016	0	0
Common Stock, $.001 par value: Authorized: 500,000,000 shares; Issued and outstanding: 109,763,967 shares at December 31, 2017 and 111,053,734 shares at December 31, 2016	110	111
Additional paid in capital	1,212,798	1,181,230
Accumulated deficit	(636,227)	(615,051)
Accumulated other comprehensive loss	(5,097)	(13,508)
Total stockholders’ equity	571,584	552,782
Total liabilities and stockholders’ equity	$ 891,072	$ 783,496