CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2013		Mar. 31, 2012
Revenue:
Royalties	$ 66,222		$ 62,043
Contract revenue	644		820
Total revenue	66,866		62,863
Operating costs and expenses:
Cost of revenue	5,249	[1]	7,163	[1]
Research and development	32,848	[1]	38,394	[1]
Marketing, general and administrative	25,105	[1]	34,834	[1]
Restructuring charges	2,206		0
Costs of restatement and related legal activities	17		30
Total operating costs and expenses	65,425		80,421
Operating income (loss)	1,441		(17,558)
Interest income and other income (expense), net	(20)		98
Interest expense	(7,312)		(6,580)
Interest and other income (expense), net	(7,332)		(6,482)
Loss before income taxes	(5,891)		(24,040)
Provision for income taxes	4,511		3,850
Net loss	$ (10,402)		$ (27,890)
Net loss per share:
Basic (in dollars per share)	$ (0.09)		$ (0.25)
Diluted (in dollars per share)	$ (0.09)		$ (0.25)
Weighted average shares used in per share calculation:
Basic (in shares)	111,599		110,358
Diluted (in shares)	111,599		110,358

[1] Includes stock-based compensation