Condensed Consolidated Statements of Operations And Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Revenues:
Product sales, net	$ 71,086	$ 0
Total revenues	71,086	0
Operating expenses:
Cost of product sales	950	0
Research and development	48,947	51,882
Sales, general and administrative	58,636	28,050
Total operating expenses	108,533	79,932
Loss from operations	(37,447)	(79,932)
Other (expense) income:
Deferred gain on real estate	201	879
Interest expense	(7,504)	0
Investment income, net	2,932	727
Total other (expense) income	(4,371)	1,606
Net loss	$ (41,818)	$ (78,326)
Net loss per common share:
Basic and diluted	$ (0.47)	$ (0.90)
Shares used in the calculation of net loss per common share:
Basic and diluted	89,526	87,283
Other comprehensive loss:
Net loss	$ (41,818)	$ (78,326)
Net unrealized (losses) gains on available-for-sale securities	(1,847)	83
Comprehensive loss	$ (43,665)	$ (78,243)