X0508 4 2023-08-28 0 0000914475 NEUROCRINE BIOSCIENCES INC NBIX 0001965808 Delaet Ingrid 12780 EL CAMINO REAL SAN DIEGO CA 92130 0 1 0 0 Chief Regulatory Officer 1 Common Stock 2023-08-28 4 S 0 1431 107.52 D 5931 D Sale of 1,431 shares of common stock issued upon vesting of 2,717 restricted stock units on August 28, 2023 to cover payroll and withholding taxes, with the balance of the shares (1,286) maintained by the Reporting Person; the disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person on September 13, 2022. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan. /s/ Darin Lippoldt, Attorney-in-Fact 2023-08-30