X0407 4 2023-04-24 0 0000914475 NEUROCRINE BIOSCIENCES INC NBIX 0001727606 ROBERTS EIRY 12780 EL CAMINO REAL SAN DIEGO CA 92130 0 1 0 0 Chief Medical Officer 1 Common Stock 2023-04-24 4 S 0 14400 103.4763 D 26644 D The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted on February 23, 2023. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan. Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $102.84 to $104.15. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. /s/ Darin Lippoldt, Attorney-in-Fact 2023-04-26