X0206 3 2023-02-09 0 0000914475 NEUROCRINE BIOSCIENCES INC NBIX 0001965808 Delaet Ingrid 12780 EL CAMINO REAL SAN DIEGO CA 92130 0 1 0 0 Chief Regulatory Officer Common Stock 3382 D Incentive Stock Option 106.02 2031-02-01 Common Stock 3359 D Non-Qualified Stock Option 106.02 2031-02-01 Common Stock 9367 D Incentive Stock Option 79.02 2032-01-31 Common Stock 827 D Non-Qualified Stock Option 79.02 2032-01-31 Common Stock 12261 D Restricted Stock Unit Common Stock 4717 D Restricted Stock Unit Common Stock 5435 D Restriced Stock Unit Common Stock 3202 D Option granted February 1, 2021 and vests at 25% upon first anniversary (February 1, 2022) and remaining 75% vesting in 36 equal monthly installments beginning on March 1, 2022. Option granted January 31, 2022 and vests monthly over four years. 1/4 of the Restricted Stock Units vested on February 1, 2022 and February 1, 2023. The remaining units vest equally on each of February 1, 2024 and February 1, 2025. Each Restricted Stock Unit represents a contingent right to receive one share of the Issuer Common Stock. 1/2 of the Restricted Stock Units vested on August 27, 2022. The remaining units will vest on August 27, 2023. 1/4 of the Restricted Stock Units vested on January 31, 2023. The remaining units vest equally on each of January 31, 2024, January 31, 2025, January 26, 2026. /s/ Darin Lippoldt, Attorney-in-Fact 2023-02-15