X0206 3 2022-02-04 0 0000914475 NEUROCRINE BIOSCIENCES INC NBIX 0001909817 Boyer David W. 12780 EL CAMINO REAL SAN DIEGO CA 0 1 0 0 Chief Corp. Affairs Officer Common Stock 2075 D Incentive Stock Option 89.23 2029-10-01 Common Stock 4480 D Non-Qualified Stock Option 89.23 2029-10-01 Common Stock 43724 D Incentive Stock Option 102.90 2030-02-06 Common Stock 479 D Non-Qualified Stock Option 102.90 2030-02-06 Common Stock 11024 D Incentive Stock Option 117.63 2031-02-08 Common Stock 1281 D Non-Qualified Stock Option 117.63 2031-02-08 Common Stock 33754 D Incentive Stock Option 79.02 2032-01-31 Common Stock 1190 D Non-Qualified Stock Option 79.02 2032-01-31 Common Stock 55907 D Restricted Stock Unit Common Stock 10927 D Restricted Stock Unit Common Stock 1823 D Restricted Stock Unit Common Stock 5314 D Restriced Stock Unit Common Stock 8384 D Option granted October 1, 2019 and vests at 25% upon first anniversary (October 1, 2020) and remaining 75% vesting in 36 equal monthly installments beginning November 1, 2020. Option granted February 6, 2020 and vests monthly over four years. Option granted February 8, 2021 and vests monthly over four years. Option granted January 31, 2022 and vests monthly over four years. 1/4 of the Restricted Stock Units vested on October 1, 2020 and October 1, 2021. The remaining units vest equally on each of October 1, 2022, October 1, 2023. Each Restricted Stock Unit represents a contingent right to receive one share of the Issuer Common Stock. 1/4th of the Restricted Stock Units vested on February 6, 2021. The remaining units vest equally on each of February 6, 2022, February 6, 2023, February 6, 2024. The Restricted Stock Units will vest annually at 1/4 of the units vesting on each of February 8, 2022, February 8, 2023, February 8, 2024, and February 8, 2025. The Restricted Stock Units will vest annually at 1/4 of the units vesting on each of January 31, 2023, January 31, 2024, January 31, 2025, January 26, 2026. /s/ David Boyer 2022-02-09