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Significant Collaboration and Licensing Agreements - Additional Information (Detail) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 27 Months Ended 28 Months Ended 123 Months Ended
May 31, 2020
Dec. 31, 2019
Jun. 30, 2019
Mar. 31, 2015
Jun. 30, 2010
Sep. 30, 2020
Jun. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Jun. 30, 2017
Sep. 30, 2020
Jul. 31, 2020
Apr. 30, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Revenue from contract with customer           $ 258.5   $ 222.1 $ 798.0 $ 544.0            
Takeda | Collaborative Arrangement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Upfront payments made                             $ 120.0  
Potential milestone payments           1,900.0     1,900.0   $ 1,900.0     $ 1,900.0    
Idorsia | Collaborative Arrangement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Upfront payments made $ 45.0                              
Incremental funding provided $ 7.2                              
Research collaboration term 2 years                              
Potential commercial milestone payments           750.0     750.0   750.0     750.0    
Collaboration termination notice period 90 days                              
Idorsia | Collaborative Arrangement | NBI-827104                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Potential milestone payments           365.0     365.0   365.0     365.0    
Idorsia | Collaborative Arrangement | Development Product Candidates                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Potential milestone payments           620.0     620.0   620.0     620.0    
Xenon | Collaborative Arrangement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Collaboration termination notice period   90 days                            
Voyager | Collaborative Arrangement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Termination notice period, before first commercial sale     180 days                          
Termination notice period, after date of notice     1 year                          
B I A L | Collaborative Arrangement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Potential commercial milestone payments           75.0     $ 75.0   75.0     75.0    
Milestone payment                               $ 20.0
Minimum sales requirement period                 2 years              
Mitsubishi Tanabe | Collaborative Arrangement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Collaboration termination notice period       180 days                        
Deferred revenue recognized           0.5     $ 1.8   2.6          
Deferred revenue, balance           7.6     7.6   7.6     7.6    
Upfront payments received       $ 30.0                        
Revenue from contract with customer                       $ 15.0 $ 19.8      
Potential milestone payment receipts           70.0     70.0   70.0     70.0    
Mitsubishi Tanabe | Collaborative Arrangement | Patents | Minimum                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Patent term       10 years                        
AbbVie | Collaborative Arrangement                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Collaboration termination notice period         180 days                      
Revenue from contract with customer         $ 75.0   $ 30.0             165.0    
Potential milestone payment receipts           $ 366.0     $ 366.0   $ 366.0     $ 366.0    
AbbVie | Collaborative Arrangement | Patents | Minimum                                
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                                
Patent term         10 years