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Statements Of Cash Flows (USD $)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (27,872,293) $ (20,321,812) $ (14,573,353)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 1,252,142 1,238,044 1,327,794
Share-based compensation 6,931,438 3,553,414 1,437,174
Loss on disposal of equipment and other assets 126 621 0
Realized loss (gain) on available for sale securities 12,226 (5,220) 1,671
Changes in operating assets and liabilities:      
Prepaid and other assets 443,639 248,411 (125,463)
Accounts payable and accrued expenses 421,943 768,096 470,962
Deferred rent (50,634) (145,237) 24,668
Total adjustments 9,010,880 5,658,129 3,136,806
Net cash used in operating activities (18,861,413) (14,663,683) (11,436,547)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchase of available for sale securities (27,096,006) (16,799,888) (9,439,760)
Proceeds from redemption of available for sale securities 18,160,000 13,800,000 10,725,000
Purchases of property and equipment (78,509) (135,541) (100,649)
Payments for patent costs and other intangible assets (652,029) (1,026,736) (609,851)
Net cash (used in) provided by investing activities (9,666,544) (4,162,165) 574,740
CASH FLOWS FROM FINANCING ACTIVITIES:      
Net proceeds from issuance of common stock in public and private offerings 27,327,975 17,555,674 10,556,754
Net proceeds from exercise of options and warrants 1,147,380 1,381,694 330,938
Principal payments on capital lease obligation (22,928) (26,731) (25,845)
Net cash provided by financing activities 28,452,427 18,910,637 10,861,847
NET CHANGE IN CASH AND CASH EQUIVALENTS (75,530) 84,789 40
CASH AND CASH EQUIVALENTS, beginning of year 298,227 213,438 213,398
CASH AND CASH EQUIVALENTS, end of year 222,697 298,227 213,438
SUPPLEMENTAL CASH FLOW INFORMATION:      
Cash paid for interest expense 7,095 8,843 5,716
Cash paid for income taxes 0 0 0
SUPPLEMENTAL SCHEDULE OF NON-CASH ACTIVITIES:      
Key-man life insurance premiums (Note 3) 0 29,330 45,780
Purchases of leasehold improvements (Note 11) 0 30,462 27,572
Purchase of equipment under capital lease (Note 5) $ 0 $ 71,925 $ 0