X0201 4 2003-12-02 0 0000913077 AFFYMETRIX INC AFFX 0001240366 SINGER DAVID B C/O AFFYMETRIX, INC. 3380 CENTRAL EXPRESSWAY SANTA CLARA CA 95051 1 0 0 0 Common Stock 2003-12-02 4 M 0 500 .3375 A 0 D Common Stock 2003-12-02 4 S 0 500 25.76 D 26332 D Common Stock 2000 I Chevy Chase Circle Foundation Options to Purchase Common Stock .3375 2003-12-02 4 M 0 500 0 D 2005-12-20 Common Stock 500 39666 D Sold pursuant to a 10b5-1 Sales Plan entered into on August 8, 2003 by the reporting person. Held by Chevy Chase Circle Foundation which is controlled by the reporting person. 13,334 shares exercisable on 12/20/96 and 13,333 shares exercisable on each of the following: 12/20/97, 12/20/98, 12/20/99 and 12/20/00. /s/ David B. Singer 2003-12-04