X0306 4 2016-02-08 0 0000913077 AFFYMETRIX INC AFFX 0001485088 Last Andrew J. C/O AFFYMETRIX, INC. 3420 CENTRAL EXPRESSWAY SANTA CLARA CA 95051 0 1 0 0 EVP, Chief Operating Officer Common Stock 2016-02-08 4 A 0 37297 0 A 207409 D On February 8, 2016, this number of perfomance-based restricted stock units was determined to be earned with respect to the performance period ending December 31, 2015. These earned restricted stock units will vest annually over three years commencing on February 19, 2016. /s/ Siang H. Chin, Attorney-in-Fact for Andrew J. Last 2016-02-09