X0304 4 2012-01-31 0 0000913077 AFFYMETRIX INC AFFX 0001455312 Witney Frank C/O AFFYMETRIX, INC. 3420 CENTRAL EXPRESSWAY SANTA CLARA CA 95051 1 1 0 0 President and CEO Common Stock 2012-01-31 4 A 0 60000 0.00 A 250000 D On January 31, 2012, this number of performance-based restricted stock units was determined to be earned. These earned restricted stock units will vest on December 31, 2012. /s/ Siang H. Chin, Attorney-in-Fact for Frank Witney 2012-02-02