STOCKHOLDERS' EQUITY AND SHARE-BASED COMPENSATION EXPENSE, Stock Plans and Share-Based Compensation (Details) (USD $) Share data in Millions, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]
Common stock reserved for future issuance (in shares)	5.3		5.3
Common Stock, Capital Shares Reserved for Future Issuance 2012 Inducement	2.0		2.0
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	$ 1,276,000	$ 10,206,000	$ 3,110,000	$ 12,598,000
Unrecognized share-based compensation expense	10,900,000		10,900,000
Weighted-average term of unrecognized share-based compensation expense, Stock Options			2 years 7 months 17 days
Weighted-average term of unrecognized share-based compensation expense, Restricted Stock			2 years 2 months 15 days
Costs of product sales [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	262,000	340,000	429,000	712,000
Research and development [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	202,000	306,000	531,000	673,000
Selling, general and administrative [Member]
Recognized share-based compensation expense [Abstract]
Total stock-based compensation expense	$ 812,000	$ 9,560,000	$ 2,150,000	$ 11,213,000