X0202 4 2005-11-11 0000912183 CUBIST PHARMACEUTICALS INC CBST 0001263230 PEREZ ROBERT J 65 HAYDEN AVENUE LEXINGTON MA 02421 0 1 0 0 Senior Vice President Common Stock 2005-11-11 4 M 0 7000 13.25 A 11193 D Common Stock 2005-11-11 4 D 0 7000 22 D 4193 D Stock Options (Right to buy) 13.25 2005-11-11 4 M 0 7000 0 D 2003-12-02 2013-09-02 Common Stock 7000 58000 D Sold pursuant to a Rule 10(b)5-1 Plan Christopher D.T. Guiffre, Esq. - Attorney in fact 2005-11-14