CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012
Revenues:
U.S. product revenues, net	$ 239,503	$ 209,886	$ 452,751	$ 404,035
International product revenues	14,959	11,363	27,362	24,017
Service revenues	3,665	8,665	7,289	12,329
Other revenues	652	653	1,306	1,878
Total revenues, net	258,779	230,567	488,708	442,259
Costs and expenses:
Cost of product revenues	63,041	58,891	118,716	112,843
Research and development	115,190	67,206	229,399	118,378
Contingent consideration	2,586	2,694	4,639	5,523
Selling, general and administrative	49,889	40,255	98,090	84,035
Total costs and expenses	230,706	169,046	450,844	320,779
Operating income	28,073	61,521	37,864	121,480
Other income (expense):
Interest income	718	742	1,460	1,416
Interest expense	(7,250)	(8,902)	(14,434)	(17,909)
Other income (expense)	(146)	(3,113)	94	(3,293)
Total other income (expense), net	(6,678)	(11,273)	(12,880)	(19,786)
Income before income taxes	21,395	50,248	24,984	101,694
Provision for income taxes	6,153	7,125	3,654	25,777
Net income	15,242	43,123	21,330	75,917
Basic net income per common share (in dollars per share)	$ 0.23	$ 0.68	$ 0.33	$ 1.20
Diluted net income per common share (in dollars per share)	$ 0.23	$ 0.58	$ 0.32	$ 1.04
Shares used in calculating:
Basic net income per common share (in shares)	65,558,376	63,498,953	65,248,707	63,250,165
Diluted net income per common share (in shares)	67,731,976	81,166,329	67,385,141	81,001,476
Total comprehensive income	$ 14,775	$ 43,102	$ 20,887	$ 75,927