CONDENSED CONSOLIDATED BALANCE SHEETS (USD $) In Thousands, unless otherwise specified	Jun. 30, 2013	Dec. 31, 2012
Current assets:
Cash and cash equivalents	$ 205,436	$ 104,041
Short-term investments	685,080	872,188
Accounts receivable, net	101,609	93,467
Inventory	51,513	41,947
Deferred tax assets, net	18,343	14,190
Prepaid expenses and other current assets	51,476	31,217
Total current assets	1,113,457	1,157,050
Property and equipment, net	168,404	166,465
In-process research and development	272,700	272,700
Goodwill	114,130	114,130
Other intangible assets, net	142,594	152,830
Long-term investments	110,083	3,167
Other assets	60,826	66,043
Total assets	1,982,194	1,932,385
Current liabilities:
Accounts payable	30,054	45,603
Accrued liabilities	157,976	163,633
Short-term deferred revenue	5,943	6,784
Short-term contingent consideration	39,487	38,998
Other current liabilities	3,500	3,500
Total current liabilities	236,960	258,518
Long-term deferred revenue	32,282	34,091
Long-term deferred tax liabilities, net	94,486	103,081
Long-term contingent consideration	154,365	150,215
Long-term debt, net	375,086	367,811
Other long-term liabilities	29,627	27,921
Total liabilities	922,806	941,637
Commitments and contingencies (Notes D, G, L and M)
Stockholders' equity:
Preferred stock, non-cumulative; convertible, $.001 par value; authorized 5,000,000 shares; no shares issued and outstanding
Common stock, $.001 par value; authorized 150,000,000 shares; 66,013,909 and 64,713,695 shares issued and outstanding as of June 30, 2013 and December 31, 2012, respectively	66	65
Additional paid-in capital	988,721	940,969
Accumulated other comprehensive loss	(502)	(59)
Retained earnings	71,103	49,773
Total stockholders' equity	1,059,388	990,748
Total liabilities and stockholders' equity	$ 1,982,194	$ 1,932,385