-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, Hfw40IW6/5kHABq8YIxNuGZo1TkMenCbPsyq+g/INqW0pSVpjpfVVXnkv/2dTfB2 xTPHto1ZkuUCJ3u3Cj2rKQ== 0000912057-02-028104.txt : 20020722 0000912057-02-028104.hdr.sgml : 20020722 20020722164923 ACCESSION NUMBER: 0000912057-02-028104 CONFORMED SUBMISSION TYPE: 8-K PUBLIC DOCUMENT COUNT: 4 CONFORMED PERIOD OF REPORT: 20020722 ITEM INFORMATION: Other events ITEM INFORMATION: Financial statements and exhibits FILED AS OF DATE: 20020722 FILER: COMPANY DATA: COMPANY CONFORMED NAME: TITAN PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000910267 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 943171940 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 8-K SEC ACT: 1934 Act SEC FILE NUMBER: 001-13341 FILM NUMBER: 02707918 BUSINESS ADDRESS: STREET 1: 400 OYSTER POINT BLVD STREET 2: SUITE 505 CITY: SAN FRANCISCO STATE: CA ZIP: 94080 BUSINESS PHONE: 4152444990 MAIL ADDRESS: STREET 1: 400 OYSTER POINT BLVD STREET 2: SUITE 505 CITY: SAN FRANCISCO STATE: CA ZIP: 94080 8-K 1 a2084986z8-k.htm FORM 8-K

 

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of
the Securities Exchange Act 1934

Date of Report:  July 22, 2002

Titan Pharmaceuticals, Inc.
(Exact name of registrant as specified in charter)

 

Delaware

 

0-27436

 

94-3171940

(State or other jurisdiction
of incorporation)

 

(Commission File Number)

 

(IRS Employer Identification No.)

 

400 Oyster Point Blvd., Suite 505, South San Francisco, California

 

94080

(Address of principal executive offices)

 

(Zip Code)

 

Registrant’s telephone number, including area code:  (650) 244-4990

 

 

 



 

Item 5.    Other Events

On July 22, 2002, the Registrant announced that Novartis Pharma AG has completed a study evaluating the potential effect of iloperidone, an antipsychotic medication in development, on the EKG profile of patients receiving the drug.

Reference is made to the related press release filed as Exhibit 20.1 hereto, which is incorporated by reference herein.

Item 7. Financial Statements, Pro Forma Financial Information and Exhibits

(c)           Exhibits

20.1   Press Release dated July 22, 2002

 

 

2



 

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

TITAN PHARMACEUTICALS, INC.

 

 

 

 

By:

/s/ Robert E. Farrell

 

 

Robert E. Farrell, Executive Vice President and
Chief Financial Officer

Dated:  July 22, 2002

 

3




EX-20.1 3 a2084986zex-20_1.htm EXHIBIT 20.1

 

Exhibit 20.1

 

 

Company:

 

Media:

 

Investors:

Alison Roselli

 

Rebecca Novak

 

Robert Ferris

Director, Corporate Communications

 

GCI Group

 

GCI Group

650-244-4993

 

212-537-8116

 

212-537-8025

 

FOR IMMEDIATE RELEASE

 

TITAN ANNOUNCES COMPLETION BY NOVARTIS PHARMA AG

OF EKG STUDY FOR ILOPERIDONE

 

Conference Call to Discuss the Iloperidone Development Program
is Scheduled for July 22, 1:00 PM PDT (4:00 PM EDT)

 

South San Francisco, CA — July 22, 2002 — Titan Pharmaceuticals, Inc. (ASE: TTP) today announced that Novartis Pharma AG has completed a study evaluating the potential effect of iloperidone, an antipsychotic medication in development, on the EKG profile of patients receiving the drug.

 

The study was a six-week evaluation of approximately 150 patients with schizophrenia, who were randomized to receive iloperidone at doses of 8 mg bid, 12 mg bid or 24 mg qd, or one of two currently approved drugs.  A primary endpoint of the study was evaluation of the change in QTc interval from baseline to week six.

 

The study indicated that results for iloperidone were roughly comparable to that for ziprasidone, one of the approved agents in the study.  The potential of these data to support any possible regulatory submission for iloperidone is not currently known.  In addition, even if approvable, this may potentially limit the opportunity of iloperidone as first line therapy for schizophrenia.

 

Based upon these results, Novartis and Titan will further evaluate strategic alternatives for the iloperidone development program to determine any next steps, which may include further discussion with regulatory agencies.

 

Titan will be holding a conference call today at 1:00 PM Pacific Daylight Time (4:00 PM Eastern Daylight Time) to discuss the status of the iloperidone development program.  The conference call will be broadcast live over the Internet at www.titanpharm.com.  Webcast listeners should log on at least 10 minutes prior to the scheduled start time of the call to register and download or install any required audio software.

 

 



 

About Titan

Titan Pharmaceuticals, Inc. (ASE:TTP) is a biopharmaceutical company focused on the development and commercialization of novel treatments for central nervous system disorders, cancer and other serious and life-threatening diseases.  Titan has a deep pipeline of products utilizing novel technologies that have the potential to significantly improve the treatment of these diseases.  Titan also establishes important partnerships with multinational pharmaceutical companies and government institutions for the development of its products.

 

The press release may contain “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934.  Such statements include, but are not limited to, any statements relating to the Company’s development program and any other statements that are not historical facts.  Such statements involve risks and uncertainties, including, but not limited to, those risks and uncertainties relating to difficulties or delays in development, testing, regulatory approval, production and marketing of the Company’s drug candidates, unexpected adverse side effects or inadequate therapeutic efficacy of the Company’s drug candidates that could slow or prevent product development or commercialization, the uncertainty of patent protection for the Company’s intellectual property or trade secrets and the Company’s ability to obtain additional financing if necessary.  Such statements are based on management’s current expectations, but actual results may differ materially due to various factors, including those risks and uncertainties mentioned or referred to in this press release.

 

# # #

 

 

 

2




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