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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AAR CORP COM 000361105   5,035,160 46,000 SH   OTR   46,000 0 0
ABIVAX SA SPONSORED ADS 00370M103   222,700 2,000 SH   OTR   2,000 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109   40,623,752 1,736,800 SH   OTR   1,736,800 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109   152,680 11,000 SH   OTR   11,000 0 0
AFFIRM HLDGS INC COM CL A 00827B106   4,948,560 108,000 SH   OTR   108,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104   192,289,720 5,684,000 SH   OTR   5,684,000 0 0
ALEANNA INC *W EXP 12/13/202 01444V111   801,900 990,000 SH   OTR   990,000 0 0
ALEANNA INC COM CL A 01444V103   649,936 78,400 SH   OTR   78,400 0 0
ALKERMES PLC SHS G01767105   735,488 20,800 SH   OTR   20,800 0 0
ALPHABET INC CAP STK CL C 02079K107   285,778,825 996,231 SH   OTR   996,231 0 0
ALTIMMUNE INC COM NEW 02155H200   85,008 27,600 SH   OTR   27,600 0 0
ALUMIS INC COM 022307102   242,330 11,000 SH   OTR   11,000 0 0
ALVOTECH ORDINARY SHARES L01800108   684,885 199,675 SH   OTR   199,675 0 0
AMAZON COM INC COM 023135106   878,564,918 4,218,394 SH   OTR   4,218,394 0 0
AMICUS THERAPEUTIC COM 03152W109   231,360 16,000 SH   OTR   16,000 0 0
AMKOR TECHNOLOGY INC COM 031652100   4,683,120 104,000 SH   OTR   104,000 0 0
AON PLC SHS CL A G0403H108   811,029,294 2,512,638 SH   OTR   2,512,638 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   241,380 6,000 SH   OTR   6,000 0 0
ARAMARK COM 03852U106   248,730,373 6,135,431 SH   OTR   6,135,431 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   612,560 26,000 SH   OTR   26,000 0 0
ARDELYX INC COM 039697107   137,770 23,000 SH   OTR   23,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   990,660 15,800 SH   OTR   15,800 0 0
ASSEMBLY BIOSCIENCES INC COM NEW 045396207   34,065,623 1,227,590 SH   OTR   1,227,590 0 0
ASTRAZENECA PLC ORD G0593M107   44,670,133 226,499 SH   OTR   226,499 0 0
ATRIUM THERAPEUTICS INC COM 04965N104   4,670,943 349,360 SH   OTR   349,360 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306   13,675,880 916,000 SH   OTR   916,000 0 0
AXSOME THERAPEUTICS INC. COM 05464T104   676,080 4,000 SH   OTR   4,000 0 0
BAIDU INC SPON ADR REP A 056752108   49,446,525 443,785 SH   OTR   443,785 0 0
BEAM THERAPEUTICS INC COM 07373V105   241,509,806 10,134,696 SH   OTR   10,134,696 0 0
BELITE BIO INC SPONSORED ADS 07782B104   207,272 1,300 SH   OTR   1,300 0 0
BEONE MEDICINES LTD SPONSORED ADS 07725L102   326,667 1,100 SH   OTR   1,100 0 0
BETA BIONICS INC COM 08659B102   36,151,358 3,607,920 SH   OTR   3,607,920 0 0
BEYOND MEAT INC COM 08862E109   13,330 19,000 SH   OTR   19,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103   228,480 24,000 SH   OTR   24,000 0 0
BITWISE 10 CRYPTO INDEX ETF UNIT BENEFICIAL 091749101   26,898,021 603,000 SH   OTR   603,000 0 0
BLUE GOLD LTD *W EXP 04/01/203 G1331C112   60,000 300,000 SH   OTR   300,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107   468,785,421 7,470,684 SH   OTR   7,470,684 0 0
BRIDGEBIO PHARMA INC COM 10806X102   695,479,282 9,365,463 SH   OTR   9,365,463 0 0
BRIGHTSPRING HEALTH SVCS INC COM 10950A106   68,900,370 1,617,000 SH   OTR   1,617,000 0 0
BROADCOM INC COM 11135F101   550,773,045 1,779,500 SH   OTR   1,779,500 0 0
C4 THERAPEUTICS INC COM STK 12529R107   73,640 28,000 SH   OTR   28,000 0 0
CANOPY GROWTH CORPORATION COM NEW 138035704   28,476 30,000 SH   OTR   30,000 0 0
CAPRICOR THERAPEUTICS INC COM NEW 14070B309   1,246,400 41,000 SH   OTR   41,000 0 0
CARDINAL HEALTH INC COM 14149Y108   77,762,080 368,000 SH   OTR   368,000 0 0
CECO ENVIRONMENTAL CORP COM 125141101   13,941,720 234,000 SH   OTR   234,000 0 0
CELCUITY INC COM 15102K100   456,560 4,000 SH   OTR   4,000 0 0
CENCORA INC COM 03073E105   314,140 1,000 SH   OTR   1,000 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   191,013,480 4,809,000 SH   OTR   4,809,000 0 0
CG ONCOLOGY INC COM 156944900   13,536,000 200,000 SH Call OTR   200,000 0 0
CG ONCOLOGY INC COM 156944100   45,616,320 674,000 SH   OTR   674,000 0 0
CITIGROUP INC COM NEW 172967424   5,330,270 47,000 SH   OTR   47,000 0 0
COGENT BIOSCIENCES INC COM 19240Q201   654,330 17,000 SH   OTR   17,000 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   302,839,719 8,338,098 SH   OTR   8,338,098 0 0
CUMMINS INC COM 231021106   4,842,180 9,000 SH   OTR   9,000 0 0
DIANTHUS THERAPEUTICS INC COM 252828108   70,157,120 836,000 SH   OTR   836,000 0 0
DISNEY WALT CO COM 254687106   231,465,341 2,401,591 SH   OTR   2,401,591 0 0
DYNE THERAPEUTICS INC COM 26818M108   181,300 10,000 SH   OTR   10,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106   36,271,617 2,871,862 SH   OTR   2,871,862 0 0
ENCOMPASS HEALTH CORP COM 29261A100   290,190 3,000 SH   OTR   3,000 0 0
ENTEGRIS INC COM 29362U104   5,334,420 45,500 SH   OTR   45,500 0 0
ERASCA INC COM 29479A108   291,240 18,000 SH   OTR   18,000 0 0
EVOLENT HEALTH INC CL A 30050B101   31,920 14,000 SH   OTR   14,000 0 0
EXELIXIS INC COM 30161Q104   562,331,219 13,111,010 SH   OTR   13,111,010 0 0
FISERV INC COM 337738108   4,798,800 86,000 SH   OTR   86,000 0 0
FLEXTRONICS INTL LTD ORD Y2573F102   5,105,880 78,000 SH   OTR   78,000 0 0
FORMFACTOR INC COM 346375108   5,479,935 56,500 SH   OTR   56,500 0 0
GARRETT MOTION INC COM 366505105   4,996,750 275,000 SH   OTR   275,000 0 0
GDS HLDGS LTD SPONSORED ADS 36165L108   11,764,680 292,000 SH   OTR   292,000 0 0
GE HEALTHCARE TECHNOLOGIES I COMMON STOCK 36266G107   213,540 3,000 SH   OTR   3,000 0 0
GENEDX HOLDINGS CORP COM CL A 81663L200   321,100 5,000 SH   OTR   5,000 0 0
GERON CORP COM 374163103   64,070 43,000 SH   OTR   43,000 0 0
GLAUKOS CORP COM 377322102   279,916 2,600 SH   OTR   2,600 0 0
GLOBALFOUNDRIES INC ORDINARY SHARES G39387108   4,670,400 105,000 SH   OTR   105,000 0 0
GLOBUS MED INC CL A 379577208   344,640 4,000 SH   OTR   4,000 0 0
GRAIL INC COM 384747101   168,150,389 3,253,684 SH   OTR   3,253,684 0 0
GRIFOLS S A SP ADR REP B NVT 398438408   224,560 28,000 SH   OTR   28,000 0 0
GUARDANT HEALTH INC COM 40131M109   738,960 8,000 SH   OTR   8,000 0 0
HEALTHCARE RLTY TR CL A COM 42226K105   203,880 12,000 SH   OTR   12,000 0 0
HEALTHEQUITY INC COM 42226A107   233,996 2,800 SH   OTR   2,800 0 0
HIMS & HERS HEALTH INC COM CL A 433000106   207,600 10,000 SH   OTR   10,000 0 0
HYATT HOTELS CORP COM CL A 448579102   5,176,440 36,000 SH   OTR   36,000 0 0
IMMUNOVANT INC COM 45258J102   38,402,640 1,546,000 SH   OTR   1,546,000 0 0
INTER & CO INC CLASS A COM G4R20B107   4,891,420 614,500 SH   OTR   614,500 0 0
INVESCO EXCHANGE TRADED FD T S&P500 EQL WGT 46137V957   690,912,000 3,600,000 SH Put OTR   3,600,000 0 0
IONIS PHARMACEUTICALS INC COM 462222100   360,432 4,800 SH   OTR   4,800 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   91,260 26,000 SH   OTR   26,000 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108   45,630 13,000 SH   OTR   13,000 0 0
JOHNSON & JOHNSON COM 478160104   36,177,120 148,000 SH   OTR   148,000 0 0
JOYY INC ADS REPSTG COM A 46591M109   33,761,098 578,200 SH   OTR   578,200 0 0
KKR & CO INC COM 48251W104   432,141,500 4,671,800 SH   OTR   4,671,800 0 0
KRYSTAL BIOTECH INC COM 501147102   258,320 1,000 SH   OTR   1,000 0 0
LANTHEUS HLDGS INC COM 516544103   423,506,882 5,583,479 SH   OTR   5,583,479 0 0
LIQUIDIA CORPORATION COM NEW 53635D202   326,678,874 8,656,038 SH   OTR   8,656,038 0 0
LITTELFUSE INC COM 537008104   5,090,250 15,000 SH   OTR   15,000 0 0
LIVANOVA PLC SHS G5509L101   381,360 6,000 SH   OTR   6,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   1,737,397 3,319 SH   OTR   3,319 0 0
MASTEC INC COM 576323109   5,469,580 17,000 SH   OTR   17,000 0 0
MASTERCARD INCORPORATED CL A 57636Q104   217,387,576 435,071 SH   OTR   435,071 0 0
MAZE THERAPEUTICS INC COM 578784100   11,134,050 373,000 SH   OTR   373,000 0 0
MCKESSON CORP COM 58155Q103   202,753,848 234,300 SH   OTR   234,300 0 0
MERCK & CO INC COM 58933Y105   43,424,690 361,000 SH   OTR   361,000 0 0
MERIT MED SYS INC COM 589889104   206,790 3,000 SH   OTR   3,000 0 0
MICROSOFT CORP COM 594918104   867,966,842 2,344,779 SH   OTR   2,344,779 0 0
MINERVA NEUROSCIENCES INC COM NEW 603380205   14,249,125 2,365,000 SH   OTR   2,365,000 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   277,140 3,000 SH   OTR   3,000 0 0
MOLINA HEALTHCARE INC COM 60855R100   4,665,500 35,000 SH   OTR   35,000 0 0
NATERA INC COM 632307104   641,441,126 3,207,366 SH   OTR   3,207,366 0 0
NEKTAR THERAPEUTICS COM NEW 640268306   287,800 4,000 SH   OTR   4,000 0 0
NEOGENOMICS INC COM NEW 64049M209   140,980 19,000 SH   OTR   19,000 0 0
NETEASE COM INC SPONSORED ADS 64110W102   32,599,055 291,219 SH   OTR   291,219 0 0
NOVAVAX INC COM NEW 670002401   179,080 22,000 SH   OTR   22,000 0 0
NOVO-NORDISK A S ADR 670100205   28,738,500 782,000 SH   OTR   782,000 0 0
NUVALENT INC COM 670703107   307,350 3,000 SH   OTR   3,000 0 0
NUVATION BIO INC COM CL A 67080N101   124,410 29,000 SH   OTR   29,000 0 0
NVNI GROUP LIMITED *W EXP 11/01/202 G50716110   17,813 375,000 SH   OTR   375,000 0 0
OCULAR THERAPEUTIX INC COM 67576A100   152,460 18,000 SH   OTR   18,000 0 0
OMEROS CORP COM 682143102   242,880 23,000 SH   OTR   23,000 0 0
OPUS GENETICS INC COM 67577R102   4,550,000 1,000,000 SH   OTR   1,000,000 0 0
OSCAR HEALTH INC CL A 687793109   126,170 11,000 SH   OTR   11,000 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   178,200 135,000 SH   OTR   135,000 0 0
PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS G70077105   24,682,500 2,250,000 SH   OTR   2,250,000 0 0
PIPER SANDLER COMPANIES COM NEW 724078209   5,052,300 66,000 SH   OTR   66,000 0 0
PRECIGEN INC COM 74017N105   193,500 50,000 SH   OTR   50,000 0 0
PRIME MEDICINE INC COM 74168J101   4,318,134 1,240,843 SH   OTR   1,240,843 0 0
PROGYNY INC COM 74340E103   305,640 18,000 SH   OTR   18,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   669,174,692 6,348,906 SH   OTR   6,348,906 0 0
RANI THERAPEUTICS HLDGS INC COM CL A 753018100   57,314 78,000 SH   OTR   78,000 0 0
REVOLUTION MEDICINES INC *W EXP 12/17/202 76155X118   208,948 120,085 SH   OTR   120,085 0 0
REVOLUTION MEDICINES INC COM 76155X100   1,323,066,411 13,604,796 SH   OTR   13,604,796 0 0
RIO TINTO PLC SPONSORED ADR 767204100   5,019,002 53,800 SH   OTR   53,800 0 0
ROIVANT SCIENCES LTD SHS G76279101   267,997,500 9,675,000 SH   OTR   9,675,000 0 0
ROLLINS INC COM 775711104   4,967,130 93,000 SH   OTR   93,000 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104   23,649,210 493,000 SH   OTR   493,000 0 0
S&P GLOBAL INC COM 78409V104   5,104,080 12,000 SH   OTR   12,000 0 0
SABRA HEALTH CARE REIT INC COM 78573L106   269,220 14,000 SH   OTR   14,000 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   344,120 7,000 SH   OTR   7,000 0 0
SCHRODINGER INC COM 80810D103   193,120 17,000 SH   OTR   17,000 0 0
SCHWAB CHARLES CORP COM 808513105   371,752,645 3,955,657 SH   OTR   3,955,657 0 0
SELLAS LIFE SCIENCES GROUP I COM NEW 81642T209   169,200 40,000 SH   OTR   40,000 0 0
SERVICENOW INC COM 81762P102   4,286,550 41,000 SH   OTR   41,000 0 0
SOLID POWER INC *W EXP 12/08/202 83422N113   88,359 405,316 SH   OTR   405,316 0 0
STATE STR SPDR S&P 500 ETF T TR UNIT 78462F953   1,495,782,000 2,300,000 SH Put OTR   2,300,000 0 0
STOKE THERAPEUTICS INC COM 86150R107   293,040 9,000 SH   OTR   9,000 0 0
STRATEGY INC NOTE 12/0 594972AS0   32,877,339 39,500,000 PRN   OTR   39,500,000 0 0
SUMMIT MIDSTREAM CORPORATION COM 86614G101   1,760,391 58,214 SH   OTR   58,214 0 0
SUPERNUS PHARMACEUTICALS COM 868459108   206,760 4,000 SH   OTR   4,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   233,600 10,000 SH   OTR   10,000 0 0
SYNOPSYS INC COM 871607107   481,049,184 1,213,300 SH   OTR   1,213,300 0 0
TANGO THERAPEUTICS INC COM 87583X109   190,317,838 9,097,411 SH   OTR   9,097,411 0 0
TENABLE HLDGS INC COM 88025T102   4,482,475 265,000 SH   OTR   265,000 0 0
TENET HEALTHCARE CORP COM NEW 88033G407   85,325,793 452,153 SH   OTR   452,153 0 0
TERNS PHARMACEUTICALS INC COM 880881107   369,040 7,000 SH   OTR   7,000 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   10,662,480 354,000 SH   OTR   354,000 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102   433,276,322 881,485 SH   OTR   881,485 0 0
TIMKEN CO COM 887389104   5,129,070 51,000 SH   OTR   51,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   356,520 12,000 SH   OTR   12,000 0 0
TVARDI THERAPEUTICS INC COM 140755307   68,173 21,438 SH   OTR   21,438 0 0
TWIST BIOSCIENCE CORP COM 90184D100   67,841,928 1,427,650 SH   OTR   1,427,650 0 0
TYRA BIOSCIENCES INC COM 90240B106   137,145,329 3,580,818 SH   OTR   3,580,818 0 0
UNIQURE NV SHS N90064101   228,900 14,000 SH   OTR   14,000 0 0
UNITEDHEALTH GROUP INC COM 91324P102   492,935,427 1,821,706 SH   OTR   1,821,706 0 0
UROGEN PHARMA LTD COM M96088105   197,780 11,000 SH   OTR   11,000 0 0
VAXCYTE INC COM 92243G108   73,276,710 1,261,000 SH   OTR   1,261,000 0 0
VERACYTE INC COM 92337F107   225,470 7,000 SH   OTR   7,000 0 0
VERTIV HOLDINGS CO COM CL A 92537N108   4,761,020 19,000 SH   OTR   19,000 0 0
VIR BIOTECHNOLOGY INC COM 92764N102   197,120 22,000 SH   OTR   22,000 0 0
VISA INC COM CL A 92826C839   254,096,190 840,710 SH   OTR   840,710 0 0
VNET GROUP INC NOTE 2.000%10/0 90138AAE3   44,515,553 45,000,000 PRN   OTR   45,000,000 0 0
VNET GROUP INC SPONSORED ADS A 90138A103   5,229,881 623,347 SH   OTR   623,347 0 0
WABTEC COM 929740108   402,205,904 1,609,403 SH   OTR   1,609,403 0 0
WELLTOWER INC COM 95040Q104   39,542,000 200,000 SH   OTR   200,000 0 0
WESTERN ALLIANCE BANCORP COM 957638109   5,172,050 73,000 SH   OTR   73,000 0 0