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CONVERTIBLE DEBENTURES, NOTES AND OTHER DEBT (Tables)
 9 Months Ended 12 Months Ended
Sep. 30, 2025
Dec. 31, 2024
Debt Disclosure [Abstract]    
SCHEDULE OF CONVERTIBLE DEBENTURES AND NOTES, NET OF DISCOUNT

As of September 30, 2025 and December 31, 2024, special purchase agreements (SPAs) with convertible debentures and notes, net of debt discount and including accrued interest, if any, consist of the following amounts:

 

SCHEDULE OF CONVERTIBLE DEBENTURES AND NOTES, NET OF DISCOUNT

  

September 30,

2025

  

December 31,

2024

 
Current Debt          
Convertible debentures          
10% Convertible note payable, due April 23, 2022 – Bridge Investor  $35,556   $35,556 
10% Convertible note payable, due April 23, 2022 – Related Party   164,444    164,444 
10% Convertible note payable, due August 6, 2022 – Bridge Investor   200,000    200,000 
Convertible note payable   400,000    400,000 
Fall 2019 Notes          
5% Convertible note payable – Stephen Boesch   137,708    133,958 
5% Convertible note payable – Related Party   323,108    313,733 
5% Convertible note payable – Dr. Sanjay Jha (Through his family trust)   322,628    313,253 
5% Convertible note payable – CEO & CFO – Related Parties   105,734    102,659 
5% Convertible note payable – Bridge Investors   216,622    210,322 
Convertible note payable   1,105,800    1,073,925 

 

August 2021 Convertible Notes

          
5% Convertible note – Autotelic Inc– Related Party   301,927    292,552 
5% Convertible note – Bridge investors   451,082    437,075 
5% Convertible note – CFO – Related Party   90,584    87,770 
Convertible note payable   843,593    817,397 
March 2022 Notes          
16% Convertible Notes – Accredited Investors   143,579    233,687 
           
Debt for Clinical Trials – Forever Prosperity (Formerly GMP)          
2% Convertible Notes – Forever Prosperity   4,907,562    4,840,247 
           
May and June 2022 Note          
12% Convertible Notes – Accredited Investors   788,863    993,130 
           
 July 2025 Note          
10% Convertible Note – Accredited Investor   400,302    - 
           
JH Darbie PPM 2 Debt          
16% Convertible Notes - Non-related parties   2,289,595    2,183,638 
16% Convertible Notes – CEO – Related Party   125,000    125,000 
Convertible note payable   2,414,595    2,308,638 
Other Debt          
Short term debt – Bridge investors   210,000    210,000 
Short term debt from CFO – Related Party   86,050    76,050 
Short term debt – Autotelic Inc. – Related Party   2,520,000    2,085,000 
Short Term Debt from CEO – Related Party   50,000    50,000 
Short term debt   2,866,050    2,421,050 
Total of short-term convertible debentures & notes and other debt  $13,870,344    13,088,074 

As of December 31, 2024, special purchase agreements (SPAs) with convertible debentures and notes, net of debt discount and including accrued interest, if any, consist of the following amounts:

  

   December 31,
2024		   December 31,
2023		 
Current Debt          
Convertible debentures          
10% Convertible note payable, due April 23, 2022 – Bridge Investor  $35,556   $35,556 
10% Convertible note payable, due April 23, 2022 – Related Party   164,444    164,444 
10% Convertible note payable, due August 6, 2022 – Bridge Investor   200,000    200,000 
Convertible note payable   400,000    400,000 
Fall 2019 Notes          
5% Convertible note payable – Stephen Boesch   133,958    128,958 
5% Convertible note payable – Related Party   313,733    301,233 
5% Convertible note payable – Dr. Sanjay Jha (Through his family trust)   313,253    300,753 
5% Convertible note payable – CEO & CFO – Related Parties   102,659    98,559 
5% Convertible note payable – Bridge Investors   210,322    201,922 
Convertible note payable   1,073,925    1,031,425 
August 2021 Convertible Notes          
5% Convertible note – Autotelic Inc– Related Party   292,552    280,052 
5% Convertible note – Bridge investors   437,075    418,399 
5% Convertible note – CFO – Related Party   87,770    84,018 
Convertible note payable   817,397    782,469 
JH Darbie PPM Debt          
16% Convertible Notes – Non-related parties   -    311,693 
           
November/December 2021 & March 2022 Notes          
16% Convertible Notes – Accredited Investors   233,687    233,392 
           
Debt for Clinical Trials – Forever Prosperity ( Formerly GMP)          
2% Convertible Notes – Forever Prosperity   4,840,247    4,750,000 
           
May and June 2022 Note          
16% Convertible Notes – Accredited Investors   993,130    1,401,284 
           
JH Darbie PPM 2 Debt                
16% Convertible Notes - Non-related parties     2,183,638       -  
16% Convertible Notes – CEO – Related Party     125,000       -  
Convertible note payable     2,308,638       -  
Other Debt          
Short term debt – Bridge investors   210,000    210,000 
Short term debt from CFO – Related Party   76,050    35,050 
Short term debt – Autotelic Inc. – Related Party   2,085,000    1,470,000 
Short Term Debt from CEO – Related Party   50,000    50,000 
Short term debt   2,421,050    1,765,050 
Total of short term convertible debentures & notes and other debt  $13,088,074    10,675,313 

  

  

   December 31,
2024		   December 31,
2023		 
       
Long Term Debt          
JH Darbie PPM 2 Debt          
16% Convertible Notes - Non-related parties   -    1,773,468 
16% Convertible Notes – CEO – Related Party   -    125,000 
Convertible note payable   -    1,898,468 
SCHEDULE OF CONVERTIBLE NOTES, NET OF DISCOUNT

As of September 30, 2025, and December 31, 2024, the August 2021 Notes, inclusive of accrued interest, consist of the following amounts:

 

  

September 30,

2025

  

December 31,

2024

 
Autotelic Related party convertible note, 5% coupon December 2025  $301,927   $292,552 
Accredited investors convertible note, 5% coupon December 2025   451,082    437,075 
CFO Related party convertible note, 5% coupon December 2025   90,584    87,770 
Convertible notes  $843,593   $817,397 

 

  

September 30,

2025

  

December 31,

2024

 
         
Fourth Man Convertible note, 16% coupon March 2023 inclusive of accrued interest and default provision  $143,579   $233,687 
Unamortized debt discount   -    - 
Convertible notes, net  $143,579    233,687 
 

 

  

September 30,

2025

  

December 31,

2024

 
Mast Hill Convertible note, 12% coupon May 2025, inclusive of accrued interest and penalty  $788,863   $993,130 
Convertible notes, net  $788,863   $993,130 
 

As of December 31, 2024 and 2023, the August 2021 convertible notes, net of debt discount, consist of the following amounts:

  

   December 31,   December 31, 
   2024   2023 
Autotelic Related party convertible note, 5% coupon December 2024  $292,552   $280,052 
CFO Related party convertible note, 5% coupon December 2024   87,770    84,018 
Accredited investors convertible note, 5% coupon December 2024   437,075    418,399 
Convertible notes  $817,397   $782,469 
 

As of December 31, 2024, and December 31, 2023, the Fourth Man convertible note, net of debt discount, consist of the following amounts:

 

   December 31,
2024		   December 31,
2023		 
Fourth Man Convertible note, 16% coupon March 2023 inclusive of accrued interest and default provision  $233,687   $233,392 
Unamortized debt discount   -    - 
Convertible notes, net  $233,687    233,392 
  

As of December 31, 2024, and December 31, 2023, convertible note under the May 2022 Mast Financing, net of debt discount, consist of the following amounts:

 

   December 31,
2024		   December 31,
2023		 
Mast Hill Convertible note, 12% coupon May 2025, inclusive of accrued interest and penalty  $993,130   $905,484 
Convertible notes, net  $993,130   $905,484 
  

As of December 31, 2024 and 2023, convertible note under the June 2022 Blue Lake Financing, net of debt discount, consist of the following amounts:

 

   December 31,
2024		   December 31, 2023 
         
Blue Lake Convertible note, 16% coupon June 2023, inclusive of accrued interest  $-   $495,800 
Convertible notes, net  $-   $495,800 
 
SCHEDULE OF NET OF DEBT DISCOUNT
  

September 30,

2025

  

December 31,

2024

 
         
Mast Hill Convertible note, inclusive of accrued interest 10% coupon due August 2026  $569,512   $       - 
Convertible notes, gross  $569,512   $- 
Less: debt discount recorded   (203,834)   - 
Amortization of debt discount   34,624    - 
Convertible notes, net  $400,302   $- 
  
SCHEDULE OF SHORT-TERM LOANS

As of September 30, 2025 compared to December 31, 2024, other short-term advances consist of the following amounts obtained from various employees and related parties:

 

SCHEDULE OF SHORT-TERM LOANS

Other Advances 

September 30,

2025

  

December 31,

2024

 
Short term advance from CFO – Related Party  $86,050   $76,050 
Short term advance from CEO – Related Party   50,000    50,000 
Short term advances – bridge investors & others   210,000    210,000 
Short term advances – Autotelic Inc. – Related Party   2,520,000    2,085,000 
Short term advance  $2,866,050   $2,421,050 

As of December 31, 2024, other short-term advances consist of the following amounts obtained from various employees and related parties:

  

Other Advances  December 31, 2024   December 31, 2023 
Short term advance from CFO – Related Party  $76,050   $35,050 
Short term advance from CEO – Related Party   50,000    50,000 
Short term advances – bridge investors & others   210,000    210,000 
Short term advances – Autotelic Inc. – Related Party   2,085,000    1,470,000 
Short term advance  $2,421,050   $1,765,050