Share-based Compensation (Tables)

9 Months Ended

Sep. 30, 2019

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Summary of Non-cash, Share-based Compensation Expense

For the three and nine month periods ended September 30, 2019 and 2018, the Company recognized the following non-cash, share-based compensation expense in the statements of operations (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2019		2018		2019		2018
Research and development	$	14	$	26	$	59	$	92
General and administrative		15		32		65		123
Total	$	29	$	58	$	124	$	215

Summary of Stock Option Activities

Stock option transactions for the nine month period ended September 30, 2019 under the Company’s stock incentive plans were as follows:

	Number of Options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (in years)
Options outstanding at December 31, 2018		33,503		$	96.22		7.29
Granted		—			—
Exercised	—			—
Forfeited and cancelled		(820	)		607.30
Options outstanding at September 30, 2019		32,683		$	83.39		6.25
Options exercisable at September 30, 2019		30,644		$	86.48		6.18
Options vested and expected to vest		32,682		$	83.40		6.25