Share-based Compensation - Summary of Stock Option Activities (Details) - $ / shares	6 Months Ended	12 Months Ended
	Jun. 30, 2016	Dec. 31, 2015
Number of Stock Options
Number of Options, Options outstanding, beginning of period	161,278
Number of Options, Granted	442,300
Number of Options, Forfeited and cancelled	(18,713)
Number of Options, Options outstanding, end of period	584,865	161,278
Number of Options, Options exercisable, end of period	131,876
Number of Options, Options vested and expected to vest	583,632
Stock Options, Weighted Average Exercise Price
Weighted Average Exercise Price, Options outstanding, beginning of period	$ 18.30
Weighted Average Exercise Price, Granted	3.31
Weighted Average Exercise Price, Forfeited and cancelled	28.39
Weighted Average Exercise Price, Options outstanding, end of period	6.64	$ 18.30
Weighted Average Exercise Price, Options exercisable, end of period	16.50
Weighted Average Exercise Price, Options vested and expected to vest, end of period	$ 6.65
Stock Options, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Term (in years), Options outstanding	9 years 3 months 7 days	6 years 11 months 19 days
Weighted Average Remaining Contractual Term (in years), Options exercisable	7 years 5 months 5 days
Weighted Average Remaining Contractual Term (in years), Options vested and expected to vest	9 years 3 months 7 days