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Commitments and Contingencies (Details Textual)
$ in Thousands
6 Months Ended
Mar. 02, 2016
Jun. 30, 2016
USD ($)
Jun. 30, 2015
USD ($)
Aug. 01, 2013
ft²
Commitments And Contingencies [Line Items]        
Area of office facilities taken on lease | ft²       5,300
Additional operating lease term 38 months      
Lease renewal start date Oct. 01, 2016      
Lease expiration date Nov. 30, 2019      
Rent expense   $ 41 $ 40  
Royalty buy down due period   6 months    
Minimum        
Commitments And Contingencies [Line Items]        
Percentage of royalty obligation   12.50%    
Percentage of range of royalties that can be bought down   12.50%    
Maximum        
Commitments And Contingencies [Line Items]        
Percentage of royalty obligation   25.00%    
Percentage of range of royalties that can be bought down   17.00%    
Clinical Research Agreement with Duke University        
Commitments And Contingencies [Line Items]        
Agreement termination notice period   90 days    
Upon Food and Drug Administration Approval        
Commitments And Contingencies [Line Items]        
Expected milestone payments due upon approval   $ 8,000    
Upon Regulatory Marketing Approval        
Commitments And Contingencies [Line Items]        
Expected milestone payments due upon approval   $ 5,000    
CPEC        
Commitments And Contingencies [Line Items]        
Percentage of royalty obligation   5.00%