SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
X	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* BOULDER VENTURES IV ANNEX LP (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol ARCA biopharma, Inc. [ ABIO ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 04/06/2009
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	04/06/2009	04/06/2009	J(3)		49,708	D	$0	675,403	D
Common Stock	04/06/2009	04/06/2009	J(4)		3,292	D	$0	44,715	I	By Boulder Ventures IV, L.P.(2)
Common Stock	04/06/2009	04/06/2009	J(3)		518	A	$0	518	I	By BV Partners IV, LLC(1)
Common Stock	04/06/2009	04/06/2009	J(4)		31	A	$0	549	I	By BV Partners IV, LLC(2)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* BOULDER VENTURES IV ANNEX LP (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* BOULDER VENTURES IV LP (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* BV PARTNERS IV, L.L.C. (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Fidler Josh E (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* JONES ANDREW E (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* LEFKOFF KYLE (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Macks Lawrence M (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* Roshko Peter (Last) (First) (Middle) 1900 NINTH STREET, STE 200 (Street) BOULDER CO 80302 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. The shares are owned by Boulder Ventures IV (Annex), L.P. ("BV IV Annex") which is under common control with Boulder Ventures IV, L.P. ("BV IV LP"). BV Partners IV, L.L.C. ("BV IV LLC") serves as the sole General Partner of BV IV Annex, and has sole voting and investment control over the respective shares owned by BV IV Annex, and may be deemed to own beneficially the shares held by BV IV Annex. Josh E. Fidler ("Fidler"), Andrew E. Jones ("Jones"), Kyle Lefkoff ("Lefkoff"), Lawrence M. Macks ("Macks") and Peter Roshko ("Roshko") are Managing Members of BV IV LLC and share voting and dispositive power over the shares held by BV IV Annex and BV IV LP. Each of these individuals disclaims beneficial ownership of the shares reported herein, except to the extent of his respective pecuniary interest therein.

2. The shares are owned by BV IV LP which is under common control with Boulder IV Annex. BV IV LLC serves as the sole General Partner, and has sole voting and investment control over the respective shares owned by BV IV LP, and may be deemed to own beneficially the shares held by BV IV LP. Fidler, Jones, Lefkoff, Macks and Roshko are Managing Members of BV IV LLC and share voting and dispositive power over the shares held by BV IV LP. Each of these individuals disclaims beneficial ownership of the shares reported herein, except to the extent of his respective pecuniary interest therein.

3. Represents a pro rata in-kind distribution by BV IV Annex without consideration to its limited and general partners in accordance with the terms of its Limited Partnership Agreement. Includes 518 shares distributed to BV IV LLC, its general partner.

4. Represents a pro rata in-kind distribution by BV IV LP without consideration to its limited and general partners in accordance with the terms of its Limited Partnership Agreement. Includes 31 shares distributed to BV IV LLC, its general partner.

Remarks:

This report is being filed jointly by Boulder Ventures IV (Annex), L.P., Boulder Ventures IV, L.P., BV Partners IV, L.L.C., Josh E. Fidler, Andrew E. Jones, Kyle Lefkoff, Lawrence M. Macks and Peter Roshko as of the date hereof and relates to the same transaction. Exhibit 99.1 Joint Filer Information

	BOULDER VENTURES IV (ANNEX), L.P. By: BV Partners IV, L.L.C., its General Partner By: /s/ Kyle Lefkoff, Managing Member	04/08/2009
	BOULDER VENTURES IV, L.P. By: BV Partners IV, L.L.C., its General Partner By:/s/ Kyle Lefkoff, Managing Member	04/08/2009
	BV PARTNERS IV, L.L.C. By:/s/ Kyle Lefkoff, Managing Member	04/08/2009
	/s/ Josh E. Fidler	04/08/2009
	/s/ Andrew E. Jones	04/08/2009
	/s/ Kyle Lefkoff	04/08/2009
	/s/ Lawrence M. Macks	04/08/2009
	/s/ Peter Roshko	04/08/2009
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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