SC 13G 1 d949731dsc13g.htm SCHEDULE 13G SCHEDULE 13G

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

 

 

SCHEDULE 13G

Under the Securities Exchange Act of 1934

(Amendment No.     )*

 

 

ARCA biopharma, Inc.

(Name of Issuer)

Common stock

(Title of Class of Securities)

00211Y100

(CUSIP Number)

June 16, 2015

(Date of Event Which Requires Filing of this Statement)

 

 

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

¨ Rule 13d-1(b)

x Rule 13d-1(c)

¨ Rule 13d-1(d)

 

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 2 of 15 Pages

 

  1 

Names of reporting persons.

I.R.S. Identification Nos. of above persons (entities only)

 

Venrock Healthcare Capital Partners, L.P.

  2

Check the appropriate box if a member of a group (see instructions)

(a)  x1         (b)  ¨

 

  3

SEC use only

 

  4

Citizenship or place of organization

 

    Delaware

Number of

shares

beneficially

owned by

each

reporting

person

with

Sole voting power

 

    0

6

Shared voting power

 

    10,789,3242

7

Sole dispositive power

 

    0

8

Shared dispositive power

 

    10,789,3242

  9

Aggregate amount beneficially owned by each reporting person

 

    10,789,3242

10

Check if the aggregate amount in Row (9) excludes certain shares (see instructions)

 

    N/A

11

Percent of class represented by amount in Row (9)

 

    17.1%3

12

Type of reporting person (see instructions)

 

    PN

 

1. Venrock Healthcare Capital Partners, L.P. (“VHCP”); Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); VCHP Co-Investment Holdings, LLC (“Co-Invest”); VHCP Co-Investment Holdings II, LLC (“Co-Invest II”); VCHP Management, LLC; VCHP Management II, LLC; Anders Hove and Bong Koh are members of a group for the purposes of this Schedule 13G.
2. Consists of: 2,736,388 shares of common stock held directly by VHCP; 5,373,623 shares of common stock held directly by VHCP II; 500,409 shares of common stock held directly by Co-Invest; and 2,178,904 shares of common stock held directly by Co-Invest II.
3. This percentage is calculated based upon the number of the Issuer’s total outstanding shares equal to the sum of (i) 21,198,411 shares of the Issuer’s common stock outstanding as of May 11, 2015, as set forth in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 12, 2015 and (ii) 42,021,579 shares of common stock issued on June 16, 2015.


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 3 of 15 Pages

 

  1 

Names of reporting persons.

I.R.S. Identification Nos. of above persons (entities only)

 

Venrock Healthcare Capital Partners II, L.P.

  2

Check the appropriate box if a member of a group (see instructions)

(a)  x1         (b)  ¨

 

  3

SEC use only

 

  4

Citizenship or place of organization

 

    Delaware

Number of

shares

beneficially

owned by

each

reporting

person

with

Sole voting power

 

    0

6

Shared voting power

 

    10,789,3242

7

Sole dispositive power

 

    0

8

Shared dispositive power

 

    10,789,3242

  9

Aggregate amount beneficially owned by each reporting person

 

    10,789,3242

10

Check if the aggregate amount in Row (9) excludes certain shares (see instructions)

 

    N/A

11

Percent of class represented by amount in Row (9)

 

    17.1%3

12

Type of reporting person (see instructions)

 

    PN

 

1. Venrock Healthcare Capital Partners, L.P. (“VHCP”); Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); VCHP Co-Investment Holdings, LLC (“Co-Invest”); VHCP Co-Investment Holdings II, LLC (“Co-Invest II”); VCHP Management, LLC; VCHP Management II, LLC; Anders Hove and Bong Koh are members of a group for the purposes of this Schedule 13G.
2. Consists of: 2,736,388 shares of common stock held directly by VHCP; 5,373,623 shares of common stock an held directly by VHCP II; 500,409 shares of common stock held directly by Co-Invest; and 2,178,904 shares of common stock held directly by Co-Invest II.
3. This percentage is calculated based upon the number of the Issuer’s total outstanding shares equal to the sum of (i) 21,198,411 shares of the Issuer’s common stock outstanding as of May 11, 2015, as set forth in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 12, 2015 and (ii) 42,021,579 shares of common stock issued on June 16, 2015.


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 4 of 15 Pages

 

  1 

Names of reporting persons.

I.R.S. Identification Nos. of above persons (entities only)

 

VHCP Co-Investment Holdings, LLC

  2

Check the appropriate box if a member of a group (see instructions)

(a)  x1         (b)  ¨

 

  3

SEC use only

 

  4

Citizenship or place of organization

 

    Delaware

Number of

shares

beneficially

owned by

each

reporting

person

with

Sole voting power

 

    0

6

Shared voting power

 

    10,789,3242

7

Sole dispositive power

 

    0

8

Shared dispositive power

 

    10,789,3242

  9

Aggregate amount beneficially owned by each reporting person

 

    10,789,3242

10

Check if the aggregate amount in Row (9) excludes certain shares (see instructions)

 

    N/A

11

Percent of class represented by amount in Row (9)

 

    17.1%3

12

Type of reporting person (see instructions)

 

    OO

 

1. Venrock Healthcare Capital Partners, L.P. (“VHCP”); Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); VCHP Co-Investment Holdings, LLC (“Co-Invest”); VHCP Co-Investment Holdings II, LLC (“Co-Invest II”); VCHP Management, LLC; VCHP Management II, LLC, Anders Hove and Bong Koh are members of a group for the purposes of this Schedule 13G.
2. Consists of: 2,736,388 shares of common stock held directly by VHCP; 5,373,623 shares of common stock held directly by VHCP II; 500,409 shares of common stock held directly by Co-Invest; and 2,178,904 shares of common stock held directly by Co-Invest II.
3. This percentage is calculated based upon the number of the Issuer’s total outstanding shares equal to the sum of (i) 21,198,411 shares of the Issuer’s common stock outstanding as of May 11, 2015, as set forth in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 12, 2015 and (ii) 42,021,579 shares of common stock issued on June 16, 2015.


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 5 of 15 Pages

 

  1 

Names of reporting persons.

I.R.S. Identification Nos. of above persons (entities only)

 

VHCP Co-Investment Holdings II, LLC

  2

Check the appropriate box if a member of a group (see instructions)

(a)  x1         (b)  ¨

 

  3

SEC use only

 

  4

Citizenship or place of organization

 

    Delaware

Number of

shares

beneficially

owned by

each

reporting

person

with

Sole voting power

 

    0

6

Shared voting power

 

    10,789,3242

7

Sole dispositive power

 

    0

8

Shared dispositive power

 

    10,789,3242

  9

Aggregate amount beneficially owned by each reporting person

 

    10,789,3242

10

Check if the aggregate amount in Row (9) excludes certain shares (see instructions)

 

    N/A

11

Percent of class represented by amount in Row (9)

 

    17.1%3

12

Type of reporting person (see instructions)

 

    OO

 

1. Venrock Healthcare Capital Partners, L.P. (“VHCP”); Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); VCHP Co-Investment Holdings, LLC (“Co-Invest”); VHCP Co-Investment Holdings II, LLC (“Co-Invest II”); VCHP Management, LLC; VCHP Management II, LLC; Anders Hove and Bong Koh are members of a group for the purposes of this Schedule 13G.
2. Consists of: 2,736,388 shares of common stock held directly by VHCP; 5,373,623 shares of common stock held directly by VHCP II; 500,409 shares of common stock held directly by Co-Invest; and 2,178,904 shares of common stock held directly by Co-Invest II.
3. This percentage is calculated based upon the number of the Issuer’s total outstanding shares equal to the sum of (i) 21,198,411 shares of the Issuer’s common stock outstanding as of May 11, 2015, as set forth in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 12, 2015 and (ii) 42,021,579 shares of common stock issued on June 16, 2015.


CUSIP No. 00211Y100 Page 6 of 15 Pages

 

  1 

Names of reporting persons.

I.R.S. Identification Nos. of above persons (entities only)

 

VHCP Management, LLC

  2

Check the appropriate box if a member of a group (see instructions)

(a)  x1         (b)  ¨

 

  3

SEC use only

 

  4

Citizenship or place of organization

 

    Delaware

Number of

shares

beneficially

owned by

each

reporting

person

with

Sole voting power

 

    0

6

Shared voting power

 

    10,789,3242

7

Sole dispositive power

 

    0

8

Shared dispositive power

 

    10,789,3242

  9

Aggregate amount beneficially owned by each reporting person

 

    10,789,3242

10

Check if the aggregate amount in Row (9) excludes certain shares (see instructions)

 

    N/A

11

Percent of class represented by amount in Row (9)

 

    17.1%3

12

Type of reporting person (see instructions)

 

    OO

 

1. Venrock Healthcare Capital Partners, L.P. (“VHCP”); Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); VCHP Co-Investment Holdings, LLC (“Co-Invest”); VHCP Co-Investment Holdings II, LLC (“Co-Invest II”); VCHP Management, LLC; VCHP Management II, LLC; Anders Hove and Bong Koh are members of a group for the purposes of this Schedule 13G.
2. Consists of: 2,736,388 shares of common stock held directly by VHCP; 5,373,623 shares of common stock held directly by VHCP II; 500,409 shares of common stock held directly by Co-Invest; and 2,178,904 shares of common stock held directly by Co-Invest II.
3. This percentage is calculated based upon the number of the Issuer’s total outstanding shares equal to the sum of (i) 21,198,411 shares of the Issuer’s common stock outstanding as of May 11, 2015, as set forth in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 12, 2015 and (ii) 42,021,579 shares of common stock issued on June 16, 2015


CUSIP No. 00211Y100 Page 7 of 15 Pages

 

  1 

Names of reporting persons.

I.R.S. Identification Nos. of above persons (entities only)

 

VHCP Management II, LLC

  2

Check the appropriate box if a member of a group (see instructions)

(a)  x1         (b)  ¨

 

  3

SEC use only

 

  4

Citizenship or place of organization

 

    Delaware

Number of

shares

beneficially

owned by

each

reporting

person

with

Sole voting power

 

    0

6

Shared voting power

 

    10,789,3242

7

Sole dispositive power

 

    0

8

Shared dispositive power

 

    10,789,3242

  9

Aggregate amount beneficially owned by each reporting person

 

    10,789,3242

10

Check if the aggregate amount in Row (9) excludes certain shares (see instructions)

 

    N/A

11

Percent of class represented by amount in Row (9)

 

    17.1%3

12

Type of reporting person (see instructions)

 

    OO

 

1. Venrock Healthcare Capital Partners, L.P. (“VHCP”); Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); VCHP Co-Investment Holdings, LLC (“Co-Invest”); VHCP Co-Investment Holdings II, LLC (“Co-Invest II”); VCHP Management, LLC; VCHP Management II, LLC; Anders Hove and Bong Koh are members of a group for the purposes of this Schedule 13G.
2. Consists of: 2,736,388 shares of common stock held directly by VHCP; 5,373,623 shares of common stock held directly by VHCP II; 500,409 shares of common stock held directly by Co-Invest; and 2,178,904 shares of common stock held directly by Co-Invest II.
3. This percentage is calculated based upon the number of the Issuer’s total outstanding shares equal to the sum of (i) 21,198,411 shares of the Issuer’s common stock outstanding as of May 11, 2015, as set forth in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 12, 2015 and (ii) 42,021,579 shares of common stock issued on June 16, 2015.


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 8 of 15 Pages

 

  1 

Names of reporting persons.

I.R.S. Identification Nos. of above persons (entities only)

 

Koh, Bong

  2

Check the appropriate box if a member of a group (see instructions)

(a)  x1         (b)  ¨

 

  3

SEC use only

 

  4

Citizenship or place of organization

 

    United States

Number of

shares

beneficially

owned by

each

reporting

person

with

Sole voting power

 

    0

6

Shared voting power

 

    10,789,3242

7

Sole dispositive power

 

    0

8

Shared dispositive power

 

    10,789,3242

  9

Aggregate amount beneficially owned by each reporting person

 

    10,789,3242

10

Check if the aggregate amount in Row (9) excludes certain shares (see instructions)

 

    N/A

11

Percent of class represented by amount in Row (9)

 

    17.1%3

12

Type of reporting person (see instructions)

 

    IN

 

1. Venrock Healthcare Capital Partners, L.P. (“VHCP”); Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); VCHP Co-Investment Holdings, LLC (“Co-Invest”); VHCP Co-Investment Holdings II, LLC (“Co-Invest II”); VCHP Management, LLC; VCHP Management II, LLC; Anders Hove and Bong Koh are members of a group for the purposes of this Schedule 13G.
2. Consists of: 2,736,388 shares of common stock held directly by VHCP; 5,373,623 shares of common stock held directly by VHCP II; 500,409 shares of common stock held directly by Co-Invest; and 2,178,904 shares of common stock held directly by Co-Invest II.
3. This percentage is calculated based upon the number of the Issuer’s total outstanding shares equal to the sum of (i) 21,198,411 shares of the Issuer’s common stock outstanding as of May 11, 2015, as set forth in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 12, 2015 and (ii) 42,021,579 shares of common stock issued on June 16, 2015.


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 9 of 15 Pages

 

  1 

Names of reporting persons.

I.R.S. Identification Nos. of above persons (entities only)

 

Hove, Anders

  2

Check the appropriate box if a member of a group (see instructions)

(a)  x1         (b)  ¨

 

  3

SEC use only

 

  4

Citizenship or place of organization

 

    United States

Number of

shares

beneficially

owned by

each

reporting

person

with

Sole voting power

 

    0

6

Shared voting power

 

    10,789,3242

7

Sole dispositive power

 

    0

8

Shared dispositive power

 

    10,789,3242

  9

Aggregate amount beneficially owned by each reporting person

 

    10,789,3242

10

Check if the aggregate amount in Row (9) excludes certain shares (see instructions)

 

    N/A

11

Percent of class represented by amount in Row (9)

 

    17.1%3

12

Type of reporting person (see instructions)

 

    IN

 

1. Venrock Healthcare Capital Partners, L.P. (“VHCP”); Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); VCHP Co-Investment Holdings, LLC (“Co-Invest”); VHCP Co-Investment Holdings II, LLC (“Co-Invest II”); VCHP Management, LLC; VCHP Management II, LLC; Anders Hove and Bong Koh are members of a group for the purposes of this Schedule 13G.
2. Consists of: 2,736,388 shares of common stock held directly by VHCP; 5,373,623 shares of common stock held directly by VHCP II; 500,409 shares of common stock held directly by Co-Invest; and 2,178,904 shares of common stock held directly by Co-Invest II.
3. This percentage is calculated based upon the number of the Issuer’s total outstanding shares equal to the sum of (i) 21,198,411 shares of the Issuer’s common stock outstanding as of May 11, 2015, as set forth in the Issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on May 12, 2015 and (ii) 42,021,579 shares of common stock issued on June 16, 2015.


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 10 of 15 Pages

 

Introductory Note: This Schedule 13G is filed on behalf of Venrock Healthcare Capital Partners, L.P., a limited partnership organized under the laws of the state of Delaware, Venrock Capital Partners II, L.P., a limited partnership organized under the laws of the state of Delaware, VCHP Co-Investment Holdings, LLC., a limited liability company organized under the laws of the state of Delaware, VHCP Co-Investment Holdings II, LLC, a limited liability company organized under the laws of the state of Delaware, VCHP Management, LLC, a limited liability company organized under the laws of the state of Delaware, VCHP Management II, LLC, a limited liability company organized under the laws of the state of Delaware, Anders Hove and Bong Koh in respect of the shares of common stock of ARCA biopharma, Inc.

Item 1.

 

  (a) Name of Issuer:

ARCA biopharma, Inc.

 

  (b) Address of Issuer’s Principal Executive Offices:

11080 CirclePoint Road, Suite 140

Westminster, CO 80020

Item 2.

 

  (a) Name of Persons Filing:

Venrock Healthcare Capital Partners, L.P.

Venrock Healthcare Capital Partners II, L.P.

VHCP Co-Investment Holdings, LLC

VHCP Co-Investment Holdings II, LLC

VHCP Management, LLC

VHCP Management II, LLC

Anders Hove

Bong Koh

 

  (b) Address of Principal Business Office or, if none, Residence:

 

New York Office Palo Alto Office Cambridge Office
530 Fifth Avenue 3340 Hillview Avenue 55 Cambridge Parkway
22nd Floor Palo Alto, CA 94304 Suite 100
New York, NY 10036 Cambridge MA, 02142


CUSIP No. 00211Y100 Page 11 of 15 Pages

 

  (c) Citizenship:

All entities are organized in Delaware. The individuals are both United States citizens.

 

  (d) Title of Class of Securities:

Common Stock

 

  (e) CUSIP Number:

00211Y100

 

Item 3: If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Not applicable.


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 12 of 15 Pages

 

Item 4. Ownership:

 

  (a) Amount beneficially owned as of June 16, 2015:

 

Venrock Healthcare Capital Partners, L.P.

  10,789,324 (1) 

Venrock Healthcare Capital Partners II, L.P.

  10,789,324 (1) 

VHCP Co-Investment Holdings, LLC

  10,789,324 (1) 

VHCP Co-Investment Holdings, LLC

  10,789,324 (1) 

VHCP Management, LLC

  10,789,324 (1) 

VHCP Management II, LLC

  10,789,324 (1) 

Anders Hove

  10,789,324 (1) 

Bong Koh

  10,789,324 (1) 

 

  (b) Percent of class as of June 16, 2015:

 

Venrock Healthcare Capital Partners, L.P.

  17.1

Venrock Healthcare Capital Partners II, L.P.

  17.1

VHCP Co-Investment Holdings, LLC

  17.1

VHCP Co-Investment Holdings II, LLC

  17.1

VHCP Management, LLC

  17.1

VHCP Management II, LLC

  17.1

Anders Hove

  17.1

Bong Koh

  17.1

 

  (c) Number of shares to which the person has as of June 16, 2015:

 

  (i) Sole power to vote or to direct the vote:

 

Venrock Healthcare Capital Partners, L.P.

  0   

Venrock Healthcare Capital Partners II, L.P.

  0   

VHCP Co-Investment Holdings, LLC

  0   

VHCP Co-Investment Holdings II, LLC

  0   

VHCP Management, LLC

  0   

VHCP Management II, LLC

  0   

Anders Hove

  0   

Bong Koh

  0   


CUSIP No. 00211Y100 Page 13 of 15 Pages

 

  (ii) Shared power to vote or to direct the vote:

 

Venrock Healthcare Capital Partners, L.P.

  10,789,324 (1) 

Venrock Healthcare Capital Partners II, L.P.

  10,789,324 (1) 

VHCP Co-Investment Holdings, LLC

  10,789,324 (1) 

VHCP Co-Investment Holdings II, LLC

  10,789,324 (1) 

VHCP Management, LLC

  10,789,324 (1) 

VHCP Management II, LLC

  10,789,324 (1) 

Anders Hove

  10,789,324 (1) 

Bong Koh

  10,789,324 (1) 

 

  (iii) Sole power to dispose or to direct the disposition of:

 

Venrock Healthcare Capital Partners, L.P.

  0   

Venrock Healthcare Capital Partners II, L.P.

  0   

VHCP Co-Investment Holdings, LLC

  0   

VHCP Co-Investment Holdings II, LLC

  0   

VHCP Management, LLC

  0   

VHCP Management II, LLC

  0   

Anders Hove

  0   

Bong Koh

  0   

 

  (iv) Shared power to dispose or to direct the disposition of:

 

Venrock Healthcare Capital Partners, L.P.

  10,789,324 (1) 

Venrock Healthcare Capital Partners II, L.P.

  10,789,324 (1) 

VHCP Co-Investment Holdings, LLC

  10,789,324 (1) 

VHCP Co-Investment Holdings II, LLC

  10,789,324 (1) 

VHCP Management, LLC

  10,789,324 (1) 

VHCP Management II, LLC

  10,789,324 (1) 

Anders Hove

  10,789,324 (1) 

Bong Koh

  10,789,324 (1) 

 

(1) These shares are owned directly as follows: 2,736,388 shares of common stock are owned by Venrock Healthcare Capital Partners, L.P. (“VHCP”); 5,373,623 shares of common stock are owned by Venrock Healthcare Capital Partners II, L.P. (“VHCP II”); 500,409 shares of common stock are owned by VHCP Co-Investment Holdings, LLC (“Co-Invest”); and 2,178,904 shares of common stock are owned by VHCP Co-Investment Holdings II, LLC (“Co-Invest II”). VHCP Management, LLC is the general partner of VHCP and the manager of Co-Invest. VHCP Management II, LLC is the general partner of VHCP II and the manager of Co-Invest II. Messrs. Hove and Koh are the managing members of VHCP Management, LLC and VHCP Management II, LLC.

 

Item 5. Ownership of Five Percent or Less of Class:

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following  ¨


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 14 of 15 Pages

 

Item 6. Ownership of More than Five Percent on Behalf of Another Person:

Not applicable.

 

Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company:

Not applicable.

 

Item 8. Identification and Classification of Members of the Group:

Not applicable.

 

Item 9. Notice of Dissolution of Group:

Not applicable.

 

Item 10. Certification:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.


SCHEDULE 13G

 

CUSIP No. 00211Y100 Page 15 of 15 Pages

 

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: June 25, 2015

 

Venrock Healthcare Capital Partners, L.P. Venrock Healthcare Capital Partners II, L.P.
By: VHCP Management, LLC By: VHCP Management II, LLC
Its: Manager Its: General Partner
By:

/s/ David L. Stepp

By:

/s/ David L. Stepp

Name: David L. Stepp Name: David L. Stepp
Its: Authorized Signatory Its: Authorized Signatory
VHCP Co-Investment Holdings, LLC VHCP Co-Investment Holdings II, LLC
By: VHCP Management, LLC By: VHCP Management II, LLC
Its: Manager Its: General Partner
By:

/s/ David L. Stepp

By:

/s/ David L. Stepp

Name: David L. Stepp Name: David L. Stepp
Its: Authorized Signatory Its: Authorized Signatory
VHCP Management, LLC VHCP Management II, LLC
By:

/s/ David L. Stepp

By:

/s/ David L. Stepp

Name: David L. Stepp Name: David L. Stepp
Its: Authorized Signatory Its: Authorized Signatory
Anders Hove Bong Koh
By:

/s/ David L. Stepp

By:

/s/ David L. Stepp

David L. Stepp, as attorney-in-fact David L. Stepp, as attorney-in-fact


EXHIBITS

 

A: Joint Filing Agreement