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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 AHQZpXY0tQrkVx3+E2HOngHsP+BUgxQ8Nd5a7aWAhbYC0gb9okhAHDYP0xDw3+JF
 risjLtO/ogPJn1BAPoc86g==

<SEC-DOCUMENT>0000907654-03-000011.txt : 20031016
<SEC-HEADER>0000907654-03-000011.hdr.sgml : 20031016
<ACCEPTANCE-DATETIME>20031016134650
ACCESSION NUMBER:		0000907654-03-000011
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20030327
FILED AS OF DATE:		20031016

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NUVELO INC
		CENTRAL INDEX KEY:			0000907654
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				363855489
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		675 ALMANOR AVE
		CITY:			SUNNYVALE
		STATE:			CA
		ZIP:			94085
		BUSINESS PHONE:		4085248100

	MAIL ADDRESS:	
		STREET 1:		670 ALMANOR AVE
		CITY:			SUNNYVALE
		STATE:			CA
		ZIP:			94085

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HYSEQ INC
		DATE OF NAME CHANGE:	19970610

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MC CARTER III THOMAS N
		CENTRAL INDEX KEY:			0001189119

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22873
		FILM NUMBER:		03943465

	BUSINESS ADDRESS:	
		STREET 1:		C/O HYSEQ INC
		STREET 2:		670 ALMANOR AVENUE
		CITY:			SUNNYVALE
		STATE:			CA
		ZIP:			94085
		BUSINESS PHONE:		4085248100

	MAIL ADDRESS:	
		STREET 1:		C/O HYSEQ INC
		STREET 2:		670 ALMANOR AVENUE
		CITY:			SUNNYVALE
		STATE:			CA
		ZIP:			94085
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>
    <schemaVersion>X0201</schemaVersion>

    <documentType>4</documentType><periodOfReport>2003-03-27</periodOfReport>
    <issuer>
        <issuerCik>0000907654</issuerCik>
        <issuerName>NUVELO INC</issuerName>
        <issuerTradingSymbol>NUVO</issuerTradingSymbol></issuer><reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001189119</rptOwnerCik>
            <rptOwnerName>MC CARTER III THOMAS N</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NUVELO, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>675 ALMANOR AVENUE</rptOwnerStreet2>
            <rptOwnerCity>SUNNYVALE</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94085</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
<isDirector>1</isDirector><isOfficer>0</isOfficer><isTenPercentOwner>0</isTenPercentOwner><isOther>0</isOther></reportingOwnerRelationship></reportingOwner><derivativeTable><derivativeTransaction><securityTitle><value>Non-Qualified Stock Option (right to buy)</value></securityTitle><conversionOrExercisePrice><value>.91</value></conversionOrExercisePrice><transactionDate><value>2003-03-27</value></transactionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>A</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionAmounts><transactionShares><value>10000</value></transactionShares><transactionPricePerShare><value>0</value><footnoteId id="F1"/></transactionPricePerShare><transactionAcquiredDisposedCode><value>A</value></transactionAcquiredDisposedCode></transactionAmounts><exerciseDate><value>2003-03-27</value><footnoteId id="F1"/></exerciseDate><expirationDate><value>2013-03-27</value></expirationDate><underlyingSecurity><underlyingSecurityT
itle><value>Common Stock</value></underlyingSecurityTitle><underlyingSecurityShares><value>10000</value></underlyingSecurityShares></underlyingSecurity><postTransactionAmounts><sharesOwnedFollowingTransaction><value>10000</value></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>D</value></directOrIndirectOwnership><natureOfOwnership><value/></natureOfOwnership></ownershipNature></derivativeTransaction></derivativeTable><footnotes><footnote id="F1">This option is 50% exercisable as of the date of grant and 25% exercisable on 3/27/04 and 3/27/05, respectively.</footnote></footnotes><remarks/><ownerSignature><signatureName>Peter S. Garcia</signatureName><signatureDate>2003-03-31</signatureDate></ownerSignature></ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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