EXHIBIT 99.2

NUVELO, INC.

CERTIFICATION PURSUANT TO

18 U.S.C. SEC. 13350

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

     In connection with the Annual Report of Nuvelo, Inc. (the “Company”) on Form 10-K for the period ended December 31, 2002 as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Peter S. Garcia, Senior Vice President and Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. sec.1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, to my knowledge that:

(1)  The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2)  The information contained in the Report fairly presents, in all material respects, the financial condition and result of operations of the Company.

	/s/ PETER S. GARCIA
	Peter S. Garcia
	Senior Vice President and Chief Financial Officer
Date: May 14, 2003

A signed original of this written statement required by Section 906 has been provided to Nuvelo, Inc., and will be retained by Nuvelo and furnished to the Securities and Exchange Commission or its staff upon request.