Segment Reporting - Additional Information (Detail) $ in Thousands	12 Months Ended
	Dec. 31, 2016 USD ($) Segment	Dec. 31, 2015 USD ($)	Dec. 31, 2014
Segment Reporting Information [Line Items]
Number of operating business segment | Segment	1
Property, plant and equipment, net	$ 65,601	$ 71,336
United States [Member]
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 48,800	$ 54,200
Percentage of net book value of property and equipment	74.00%	76.00%
India [Member]
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 5,600	$ 6,000
Percentage of net book value of property and equipment	9.00%	8.00%
Germany and Netherlands [Member]
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 10,400	$ 11,100
Percentage of net book value of property and equipment	16.00%	16.00%
Other Countries [Member]
Segment Reporting Information [Line Items]
Property, plant and equipment, net	$ 800
Percentage of net book value of property and equipment	1.00%
Revenue [Member] | AstraZeneca [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients	29.00%	57.00%	52.00%
Revenue [Member] | UCB [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients	21.00%	13.00%	16.00%
Revenue [Member] | Ophthotech Corporation [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients	19.00%
Revenue [Member] | Roche [Member] | Customer Concentration Risk [Member]
Segment Reporting Information [Line Items]
Percentage revenue from clients	11.00%		11.00%