Property, Plant and Equipment

12 Months Ended

Dec. 31, 2016

Property Plant And Equipment [Abstract]

Property, Plant and Equipment

Note 4 — Property, Plant and Equipment

Property, plant and equipment consists of the following (in thousands):

	December 31,
	2016			2015
Building and leasehold improvements	$	75,137		$	77,665
Manufacturing equipment		44,237			35,631
Laboratory equipment		27,424			27,309
Furniture, fixtures and other equipment		26,590			24,987
Depreciable property, plant and equipment at cost		173,388			165,592
Less: accumulated depreciation		(111,243	)		(102,712	)
Depreciable property, plant and equipment, net		62,145			62,880
Construction-in-progress		3,456			8,456
Property, plant and equipment, net	$	65,601		$	71,336

Building and leasehold improvements include our manufacturing, research and development and administrative facilities and the related improvements to these facilities. Laboratory and manufacturing equipment include assets that support both our manufacturing and research and development efforts. Construction-in-progress includes assets being built to enhance our manufacturing and research and development efforts.

Depreciation expense, including depreciation of assets acquired through capital leases, for the years ended December 31, 2016, 2015, and 2014 was $13.2 million, $11.4 million, and $11.7 million, respectively.