Property, Plant and Equipment

12 Months Ended

Dec. 31, 2015

Property Plant And Equipment [Abstract]

Note 4 — Property, Plant and Equipment

Property, plant and equipment consists of the following (in thousands):

	December 31,
	2015			2014
Building and leasehold improvements	$	77,665		$	72,228
Laboratory equipment		27,309			26,975
Manufacturing equipment		35,631			25,212
Furniture, fixtures and other equipment		24,987			23,451
Depreciable property, plant and equipment at cost		165,592			147,866
Less: accumulated depreciation		(102,712	)		(93,807	)
Depreciable property, plant and equipment, net		62,880			54,059
Construction-in-progress		8,456			16,309
Property, plant and equipment, net	$	71,336		$	70,368

Building and leasehold improvements include our manufacturing, research and development and administrative facilities and the related improvements to these facilities. Laboratory and manufacturing equipment include assets that support both our manufacturing and research and development efforts. Construction-in-progress includes assets being built to enhance our manufacturing and research and development efforts, including manufacturing equipment supporting our Amikacin Inhale program at third-party contract manufacturing locations in the U.S. and Germany. Under the terms of our arrangement with certain of these contract manufacturers, during the period the equipment is being constructed, we are obligated to pay for their costs incurred to date. As of December 31, 2015 and 2014, we have recorded a total of $4.3 million and $7.2 million, respectively, in other current and other long-term liabilities related to our obligation to purchase this equipment, which is recorded in property, plant and equipment. After the assets are placed into service, this liability is recorded as a capital lease liability and will be paid over approximately three years.

Depreciation expense, including depreciation of assets acquired through capital leases, for the years ended December 31, 2015, 2014, and 2013 was $11.4 million, $11.7 million, and $13.0 million, respectively.