X0306 4 2021-09-22 0 0000906709 NEKTAR THERAPEUTICS NKTR 0001632901 Curet Myriam C/O NEKTAR THERAPEUTICS 455 MISSION BAY BLVD SOUTH, SUITE 100 SAN FRANCISCO CA 94158 1 0 0 0 Common Stock 2021-09-22 4 A 0 10200 0.00 A 29440 D Common Stock 2021-09-22 4 S 0 3665 17.78 D 25775 D Stock Option 17.78 2021-09-22 4 A 0 20400 0.00 A 2029-09-21 Common Stock 20400 20400 D Common stock was acquired pursuant to a grant of restricted stock units ("RSUs"). Each RSU awarded represents a contingent right to receive, upon vesting of the unit, one share of the Issuer's common stock. This RSU award vests in full, one year following September 22, 2021. Represents the number of shares required to be sold by the reporting person to cover tax obligations in connection with the vesting of certain RSUs held by the reporting person. This sale is mandated by the reporting person's previous election under the Issuer's equity incentive plans to require the satisfaction of tax obligations to be funded by a "sell to cover" transaction. This stock option vests in equal monthly installments over the one-year period beginning on September 22, 2021. Mark A. Wilson, Attorney-in-Fact 2021-09-24