X0306 4 2020-02-12 0 0000906709 NEKTAR THERAPEUTICS NKTR 0001227886 CHESS ROBERT C/O NEKTAR THERAPEUTICS 455 MISSION BAY BOULEVARD SOUTH SAN FRANCISCO CA 94158 1 0 0 0 Common Stock 2020-02-12 4 M 0 8000 9.24 D 284973 D Common Stock 2020-02-12 4 S 0 4401 23.32 D 280572 D Common Stock 2020-02-12 4 S 0 3599 23.72 D 276973 D Stock Option 9.24 2020-02-12 4 M 0 8000 0.00 D 2013-09-30 2020-09-13 Common Stock 8000 32000 D This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. This transaction was executed in multiple trades at prices ranging from $22.56 to $23.56. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer. This transaction was executed in multiple trades at prices ranging from $23.58 to $23.89. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer. Mark A. Wilson, Attorney-in-Fact 2020-02-14