CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) - USD ($) $ in Thousands		Total	At-the-Market Offering	Underwritten offering	Common Shares		Common Shares At-the-Market Offering	Common Shares Underwritten offering	Treasury Stock	Capital in Excess of Par Value		Capital in Excess of Par Value At-the-Market Offering	Capital in Excess of Par Value Underwritten offering	Accumulated Other Comprehensive Income/(Loss)	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2024	[1]				12,385,001
Beginning balance at Dec. 31, 2024		$ 60,737			$ 1	[1]			$ (3,000)	$ 3,659,885	[1]			$ 61	$ (3,596,210)
Beginning balance (in shares) at Dec. 31, 2024	[1]								552,307
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Shares issued under equity compensation plans (in shares)	[1]				21,709
Shares issued under equity compensation plans		7								7	[1]
Stock-based compensation		3,898								3,898	[1]
Comprehensive income (loss)		(50,904)												(22)	(50,882)
Ending balance (in shares) at Mar. 31, 2025	[1]				12,406,710
Ending balance at Mar. 31, 2025		$ 13,738			$ 1	[1]			$ (3,000)	3,663,790	[1]			(39)	(3,647,092)
Ending balance (in shares) at Mar. 31, 2025	[1]								552,307
Beginning balance (in shares) at Dec. 31, 2025		20,378,832			20,378,832
Beginning balance at Dec. 31, 2025		$ 89,832			$ 2					3,850,099				17	(3,760,286)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Shares issued under equity compensation plans (in shares)					130,034
Shares issued under equity compensation plans		4,055								4,055
Stock-based compensation		3,355								3,355
Shares issued under offering, net of underwriting discounts and offering costs (in shares)							1,325,295
Shares issued under offering, net of underwriting discounts and offering costs			$ 93,063									$ 93,063
Shares and pre-funded warrant issued during period (in shares)								7,637,931,000
Shares and pre-funded warrant issued during period (in amount)				$ 431,866				$ 1					$ 431,865
Comprehensive income (loss)		$ (45,955)												(1,051)	(44,904)
Ending balance (in shares) at Mar. 31, 2026		20,378,832			29,472,092
Ending balance at Mar. 31, 2026		$ 576,216			$ 3					$ 4,382,437				$ (1,034)	$ (3,805,190)

[1] (1)All share amounts have been retrospectively adjusted to reflect a one-for-fifteen reverse stock split (see Note 1).