CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	3 Months Ended			6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	[1]	Jun. 30, 2025	Jun. 30, 2024	[1]
Revenue:
Total revenue	$ 11,175	$ 23,489		$ 21,635	$ 45,128
Operating costs and expenses:
Cost of goods sold	0	9,740		0	18,274
Research and development (including $613 and $0 for the three months ended June 30, 2025 and 2024, respectively, from a related party; and $821 and $0 for the six months ended June 30, 2025 and 2024, respectively, from a related party)	29,886	29,724		60,366	57,132
General and administrative	17,072	20,510		41,418	40,659
Restructuring and impairment	447	13,289		616	14,264
Total operating costs and expenses	47,405	73,263		102,400	130,329
Loss from operations	(36,230)	(49,774)		(80,765)	(85,201)
Non-operating income (expense):
Non-cash interest expense on liabilities related to the sales of future royalties	(5,394)	(6,408)		(10,368)	(11,939)
Interest income	1,969	3,901		4,843	8,121
Other income (expense), net (including income of $540 and $0 for the three months ended June 30, 2025 and 2024, respectively, from a related party; and income of $861 and $0 for the six months ended June 30, 2025 and 2024, respectively, from a related party)	260	(36)		526	(135)
Total non-operating income (expense), net	(3,165)	(2,543)		(4,999)	(3,953)
Loss before provision (benefit) for income taxes and equity method investment	(39,395)	(52,317)		(85,764)	(89,154)
Provision (benefit) for income taxes	(188)	46		(136)	11
Loss before equity method investment	(39,207)	(52,363)		(85,628)	(89,165)
Loss from equity method investment	(2,386)	0		(6,847)	0
Net loss	$ (41,593)	$ (52,363)		$ (92,475)	$ (89,165)
Basic net loss per share (in dollars per share)	$ (2.95)	$ (3.76)		$ (6.57)	$ (6.63)
Diluted net loss per share (in dollars per share)	$ (2.95)	$ (3.76)		$ (6.57)	$ (6.63)
Weighted average shares outstanding used in computing basic net loss per share (in shares)	14,087,307	13,921,378		14,074,545	13,452,164
Weighted average shares outstanding used in computing diluted net loss per share (in shares)	14,087,307	13,921,378		14,074,545	13,452,164
Product sales
Revenue:
Total revenue	$ 0	$ 6,640		$ 0	$ 12,674
Non-cash royalty revenue related to the sales of future royalties
Revenue:
Total revenue	11,175	16,790		21,635	32,298
License, collaboration and other revenue
Revenue:
Total revenue	$ 0	$ 59		$ 0	$ 156

[1] All share and per share amounts have been retrospectively adjusted to reflect a one-for-fifteen reverse stock split (see Note 6).