Restructuring, Impairment and Costs of Terminated Program - Narrative (Details) - USD ($)	1 Months Ended		3 Months Ended						9 Months Ended		12 Months Ended
	Jun. 30, 2023	Apr. 30, 2022	Sep. 30, 2024	Jun. 30, 2024	Mar. 31, 2024	Sep. 30, 2023	Jun. 30, 2023	Mar. 31, 2023	Sep. 30, 2024	Sep. 30, 2023	Dec. 31, 2023
Restructuring Cost and Reserve [Line Items]
Non-cash impairment charges			$ 0		$ 0	$ 10,567,000				$ 35,329,000
Third St. Facility
Restructuring Cost and Reserve [Line Items]
Non-cash impairment charges				$ 4,400,000			$ 6,200,000
2022 Restructuring Plan | Mission Bay Facility
Restructuring Cost and Reserve [Line Items]
Non-cash impairment charges						1,500,000	$ 7,100,000
2023 Restructuring Plan
Restructuring Cost and Reserve [Line Items]
Non-cash impairment charges						1,700,000				$ 1,300,000
2023 Restructuring Plan | Mission Bay Facility
Restructuring Cost and Reserve [Line Items]
Non-cash impairment charges				$ 3,900,000		$ 9,100,000		$ 11,500,000
Restructuring Plan
Restructuring Cost and Reserve [Line Items]
Contract termination and other costs included in accrued expenses			$ 3,200,000						$ 3,200,000		$ 3,000,000
Measurement Input, Market Participant Subtenant Borrowing Rate
Restructuring Cost and Reserve [Line Items]
Operating lease, measurement input								7.90%
Sublease income, measurement input				6.20%		8.70%	8.50%
Employee Severance
Restructuring Cost and Reserve [Line Items]
Restructuring, impairment, and costs of terminated program						$ 535,000	$ 1,943,000	$ 5,483,000	0
Payments during the period						887,000	6,624,000	3,299,000	196,000
Employee Severance | 2022 Restructuring Plan
Restructuring Cost and Reserve [Line Items]
Workforce termination, percentage		70.00%
Restructuring, impairment, and costs of terminated program						0	0	0	0
Payments during the period						0	0	3,299,000	0
Employee Severance | 2023 Restructuring Plan
Restructuring Cost and Reserve [Line Items]
Workforce termination, percentage	60.00%
Restructuring, impairment, and costs of terminated program						535,000	1,943,000	5,483,000	0		$ 7,900,000
Payments during the period					$ 200,000	$ 887,000	$ 6,624,000	$ 0	$ 196,000